EMDataResource Pseudotorsion Plot Beta Server
RNA adopts complex three-dimensional folding patterns and has key roles in many cellular functions. Many cryoEM-derived structures contain RNA, including ribosomal particles, spliceosomes, RNA viruses, and polymerase complexes, yet procedures for validation of RNA structures are not as well developed as those for proteins.
This prototype web-service for virtual torsion angle validation of RNA structures can be applied to structures determined using cryo-EM as well as other structural methods. Virtual torsion angle plots for nucleic acids are analogous to Ramachandran plots for proteins. The tool evaluates single structures, either by file upload (mmCIF or PDB format) or by entering a PDB id.
The research community has developed simplified ways to represent nucleic acid backbone conformation through use of virtual torsion angles1-3. A common scheme is to define two virtual torsion angles (pseudotorsions), eta (η) and theta (θ) for a nucleotide triplet. The measured (η,θ) pair defines the backbone conformation relative to central residue (i).
The server calculates three varieties of pseudotorsion angles, as shown in the image below. In all definitions, phosphate atom positions are used, but the alternate atom differs: it is either the C4' atom (η,θ), C1' atom (η',θ'), or base origin4,5 position (η",θ").
Virtual torsion angles of the RNA backbone (calculated using DSSR4) are compared against the statistical distribution of a benchmark set of high quality, non-redundant6 RNA structures determined by X-ray crystallography at ≤ 2.5 Å. Separate analyses are performed based on sugar-puckering type (of ~27,000 residues in the benchmark set, ~24,000 are C3'-endo-like, ~3,000 are C2'-endo-like). Output plots and and a downloadable (csv format) table identify probable conformational outliers for any given RNA-containing structure. For comparison, RNA Suiteness7,8 scores are also provided in the csv (for residue i, suiteness of the i-1, i dinucleotide is listed. Suiteness range is 0(poor)-1(excellent). Calculation performed using DSSR).
The 2D plots permit comparison of pseudotorsion pairs for the structure being evaluated (plotted points) against population statistics of the benchmark set (smoothed contours: bar at right indicates benchmark residue count range). Outliers are marked on the plots by red crosses with residue information available on mouse hover. Summary statistics are provided below each plot to indicate the number of residues evaluated and percent outliers. Note that pseudotorsion angles cannot be calculated for terminal residues or around breaks in the polymer chain, so these are excluded from evaluation.
This tool is designed to identify regions of unusual conformation in folded RNA. Outliers can be legitimate but less-common backbone conformations, or they may indicate modelling error.
It may take several minutes to complete calculations for large structures such as ribosomes.
Please direct any questions/suggestions to help@emdataresource.org
- Olson, W. K. Configurational statistics of polynucleotide chains. An updated virtual bond model to treat effects of base stacking. Macromolecules 13, 721-728 (1980).
- Wadley, L. M., Keating, K. S., Duarte, C. M. & Pyle, A. M. Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol 372, 942-957, doi (2007).
- Keating, K. S., Humphris, E. L. & Pyle, A. M. A new way to see RNA. Q Rev Biophys 44, 433-466, doi (2011).
- Lu, X. J., Bussemaker, H. J. & Olson, W. K. DSSR: an integrated software tool for dissecting the spatial structure of RNA. Nucleic Acids Res 43, e142, doi (2015).
- Li, S., Olson, W. K., Lu, X. J. Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures. Nucleic Acids Research 47, W26-W34 (2019). doi
- Leontis, N. B., & Zirbel, C. L. Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking. In RNA 3D Structure Analysis and Prediction, N. Leontis & E. Westhof (Eds.), (Vol. 27, pp. 281-298). Springer Berlin Heidelberg. doi (2012).
- Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R.M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., Berman, H. M. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA 14, 465-81, doi (2008).
- Chen, V. B., Arendall III, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., Richardson, D. C., MolProbity: all-atom structure validation for macromolecular crystallography, Acta Cryst D 66, 12-21, doi (2010)
RNA Pseudotorsion Plots for PDB entry 4v5d
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA. Deposited 2009-03-24 X-RAY DIFFRACTION resol 3.5 Å
8091 C3'-endo RNA residues with 167 outliers ( 2.06 % ) from Eta-Theta plot
1187 C2'-endo RNA residues with 125 outliers ( 10.53 % ) from Eta-Theta plot
8091 C3'-endo RNA residues with 174 outliers ( 2.15 % ) from Eta'-Theta' plot
1187 C2'-endo RNA residues with 87 outliers ( 7.33 % ) from Eta'-Theta' plot
8091 C3'-endo RNA residues with 138 outliers ( 1.71 % ) from Eta"-Theta" plot
1187 C2'-endo RNA residues with 74 outliers ( 6.23 % ) from Eta"-Theta" plot
List of Outliers
| Model Number | Chain | Residue Type | Residue Identifier | Eta | Theta | Eta' | Theta' | Eta'' | Theta'' | Sugar Pucker | Suiteness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | AA | U | 30 | 207.4 | 300.9 | --- | --- | --- | --- | C3'endo | 0.508 |
| 1 | AA | C | 89 | 105.7 | 327.5 | 133.5 | 331.0 | 155.8 | 356.3 | C3'endo | 0.0 |
| 1 | AA | C | 91 | 221.8 | 286.5 | 259.3 | 286.4 | 294.7 | 326.2 | C3'endo | 0.076 |
| 1 | AA | A | 119 | 228.4 | 71.8 | 231.6 | 64.6 | --- | --- | C3'endo | 0.69 |
| 1 | AA | A | 243 | 232.2 | 121.0 | 239.4 | 79.7 | --- | --- | C3'endo | 0.93 |
| 1 | AA | C | 352 | 82.4 | 91.0 | 79.1 | 65.3 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 353 | 10.7 | 114.9 | 5.7 | 120.6 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 560 | 8.2 | 86.4 | 9.7 | 45.8 | 55.2 | 346.6 | C3'endo | 0.272 |
| 1 | AA | A | 563 | 105.7 | 102.7 | 103.9 | 79.7 | 98.9 | 27.7 | C3'endo | 0.213 |
| 1 | AA | U | 723 | 67.7 | 286.9 | 73.7 | 285.4 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 754 | 116.1 | 304.7 | --- | --- | --- | --- | C3'endo | 0.678 |
| 1 | AA | U | 839 | 53.4 | 6.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 841 | 346.4 | 306.9 | 326.1 | 323.6 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 992 | 316.7 | 96.4 | 291.0 | 83.5 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 1005 | 229.9 | 283.1 | 263.2 | 284.6 | --- | --- | C3'endo | 0.123 |
| 1 | AA | U | 1049 | 3.6 | 91.7 | 5.6 | 61.7 | 355.1 | 32.2 | C3'endo | 0.236 |
| 1 | AA | C | 1054 | 30.5 | 106.4 | 2.1 | 115.1 | 20.4 | 135.0 | C3'endo | 0.0 |
| 1 | AA | U | 1065 | 289.6 | 84.1 | 250.2 | 72.6 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1125 | 307.3 | 131.2 | 345.0 | 65.7 | 16.3 | 355.2 | C3'endo | 0.0 |
| 1 | AA | U | 1136 | 63.2 | 356.9 | 81.3 | 337.8 | 95.8 | 355.4 | C3'endo | 0.01 |
| 1 | AA | U | 1212 | 294.8 | 55.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1278 | 223.6 | 39.4 | 240.3 | 43.4 | --- | --- | C3'endo | 0.185 |
| 1 | AA | G | 1300 | 311.9 | 47.7 | 286.5 | 78.2 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1397 | 336.2 | 49.7 | 350.6 | 23.3 | 98.7 | 24.3 | C3'endo | 0.577 |
| 1 | AA | A | 1398 | 129.8 | 65.5 | 150.8 | 94.2 | --- | --- | C3'endo | 0.068 |
| 1 | AA | A | 1447 | 54.7 | 25.4 | 69.8 | 342.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 100 | 45.0 | 343.4 | 18.3 | 2.8 | 81.9 | 3.2 | C3'endo | 0.027 |
| 1 | BA | G | 102 | 200.5 | 54.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 154A | 119.3 | 284.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 229 | 327.1 | 348.5 | 16.4 | 341.2 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 248 | 121.3 | 304.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 272B | 241.8 | 132.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 352 | 264.0 | 111.3 | 242.9 | 101.2 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 443 | 267.9 | 82.6 | 309.6 | 63.1 | 11.2 | 16.9 | C3'endo | 0.505 |
| 1 | BA | A | 480 | 110.0 | 308.0 | --- | --- | --- | --- | C3'endo | 0.025 |
| 1 | BA | U | 504 | 322.4 | 86.2 | 324.2 | 56.5 | 334.6 | 358.8 | C3'endo | 0.432 |
| 1 | BA | G | 508 | 299.2 | 83.3 | 277.3 | 74.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 645 | 68.5 | 355.6 | 72.5 | 308.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 747 | 319.6 | 32.9 | 356.0 | 17.5 | 130.6 | 11.7 | C3'endo | 0.415 |
| 1 | BA | A | 751 | 301.4 | 99.6 | 324.6 | 118.3 | 317.5 | 122.8 | C3'endo | 0.845 |
| 1 | BA | A | 784 | 306.6 | 106.8 | 306.6 | 99.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 887 | 262.9 | 127.8 | 257.1 | 113.3 | --- | --- | C3'endo | 0.114 |
| 1 | BA | U | 958 | 294.0 | 89.4 | 350.6 | 75.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1045 | 206.6 | 72.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1046 | 4.5 | 13.3 | 5.6 | 319.3 | --- | --- | C3'endo | 0.075 |
| 1 | BA | C | 1052 | 21.2 | 132.0 | 77.7 | 142.7 | 49.1 | 168.5 | C3'endo | 0.082 |
| 1 | BA | C | 1135 | 82.6 | 265.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 1136 | 14.2 | 162.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1177 | 242.0 | 83.7 | 261.6 | 68.5 | --- | --- | C3'endo | 0.01 |
| 1 | BA | U | 1273 | 341.6 | 138.1 | 28.1 | 113.3 | 63.6 | 91.0 | C3'endo | 0.262 |
| 1 | BA | U | 1300 | 309.2 | 72.0 | 283.2 | 63.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1420 | 11.1 | 305.5 | 70.7 | 276.2 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1497 | 87.4 | 306.1 | 92.2 | 303.6 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 1509 | 282.0 | 318.9 | 282.1 | 334.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1757 | 329.5 | 356.1 | 327.5 | 336.5 | 14.8 | 345.8 | C3'endo | 0.141 |
| 1 | BA | C | 1965 | 264.6 | 341.7 | 331.2 | 295.6 | --- | --- | C3'endo | 0.045 |
| 1 | BA | A | 1971 | 17.0 | 335.2 | 359.7 | 332.3 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1981 | 299.6 | 292.1 | 350.9 | 286.2 | --- | --- | C3'endo | 0.363 |
| 1 | BA | A | 2030 | 9.1 | 107.0 | 35.5 | 101.5 | 18.8 | 76.1 | C3'endo | 0.237 |
| 1 | BA | C | 2055 | 235.9 | 48.0 | 258.1 | 57.7 | 307.6 | 122.4 | C3'endo | 0.0 |
| 1 | BA | U | 2132 | 324.4 | 19.8 | 358.2 | 345.4 | --- | --- | C3'endo | 0.113 |
| 1 | BA | G | 2206 | 97.5 | 290.8 | --- | --- | --- | --- | C3'endo | 0.018 |
| 1 | BA | U | 2218 | 31.2 | 320.5 | 47.8 | 303.3 | --- | --- | C3'endo | 0.01 |
| 1 | BA | A | 2267 | 128.6 | 33.3 | 141.1 | 32.3 | --- | --- | C3'endo | 0.708 |
| 1 | BA | G | 2282 | 202.4 | 46.2 | 214.9 | 29.1 | 204.8 | 41.6 | C3'endo | 0.614 |
| 1 | BA | C | 2424 | 92.2 | 333.9 | 86.5 | 324.0 | --- | --- | C3'endo | 0.19 |
| 1 | BA | G | 2428 | 294.0 | 101.1 | 278.7 | 95.4 | --- | --- | C3'endo | 0.015 |
| 1 | BA | C | 2440 | 347.9 | 277.4 | --- | --- | --- | --- | C3'endo | 0.3 |
| 1 | BA | G | 2502 | 333.0 | 47.1 | 351.1 | 41.8 | 138.9 | 64.2 | C3'endo | 0.0 |
| 1 | BA | G | 2505 | 341.4 | 153.2 | 341.3 | 133.6 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 2542 | 224.9 | 105.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 2689 | 101.9 | 60.6 | 124.0 | 65.8 | 164.8 | 84.6 | C3'endo | 0.0 |
| 1 | BA | A | 2712A | 87.0 | 328.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 2765 | 81.8 | 263.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2893 | 232.1 | 10.1 | 249.3 | 39.7 | --- | --- | C3'endo | 0.0 |
| 1 | BB | U | 41 | 275.2 | 330.0 | --- | --- | --- | --- | C3'endo | 0.223 |
| 1 | BB | G | 44 | 274.3 | 126.8 | 304.4 | 87.8 | 296.3 | 67.8 | C3'endo | 0.382 |
| 1 | CA | U | 30 | 208.1 | 299.3 | --- | --- | --- | --- | C3'endo | 0.498 |
| 1 | CA | C | 89 | 106.0 | 327.1 | 133.7 | 330.8 | 155.9 | 356.3 | C3'endo | 0.0 |
| 1 | CA | C | 91 | 221.7 | 286.5 | 259.2 | 286.4 | 294.6 | 326.2 | C3'endo | 0.079 |
| 1 | CA | A | 119 | 228.0 | 72.3 | 231.4 | 65.0 | --- | --- | C3'endo | 0.651 |
| 1 | CA | A | 243 | 231.6 | 120.8 | 239.1 | 79.6 | --- | --- | C3'endo | 0.932 |
| 1 | CA | C | 352 | 84.0 | 90.4 | 79.8 | 65.4 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 353 | 10.8 | 115.8 | 6.0 | 121.8 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 560 | 8.5 | 86.2 | 10.0 | 45.8 | 55.0 | 346.1 | C3'endo | 0.238 |
| 1 | CA | A | 563 | 106.5 | 103.6 | 104.6 | 80.9 | 99.2 | 28.4 | C3'endo | 0.244 |
| 1 | CA | U | 723 | 67.5 | 287.1 | 73.7 | 285.4 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 754 | 115.8 | 304.8 | --- | --- | --- | --- | C3'endo | 0.69 |
| 1 | CA | U | 839 | 53.9 | 5.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 841 | 346.3 | 307.0 | 325.8 | 323.8 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 992 | 317.0 | 96.1 | 291.0 | 83.7 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1005 | 230.3 | 283.1 | 263.5 | 284.6 | --- | --- | C3'endo | 0.125 |
| 1 | CA | U | 1049 | 3.8 | 91.6 | 5.6 | 62.1 | 356.8 | 31.9 | C3'endo | 0.235 |
| 1 | CA | C | 1054 | 30.6 | 106.9 | 1.8 | 115.1 | 20.5 | 134.2 | C3'endo | 0.0 |
| 1 | CA | U | 1065 | 289.7 | 84.1 | 250.3 | 72.6 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1125 | 307.7 | 131.5 | 345.4 | 65.8 | 16.5 | 355.0 | C3'endo | 0.0 |
| 1 | CA | U | 1136 | 63.3 | 357.0 | 81.4 | 337.8 | 95.9 | 355.6 | C3'endo | 0.01 |
| 1 | CA | U | 1212 | 295.1 | 55.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1278 | 223.7 | 39.5 | 240.6 | 43.3 | --- | --- | C3'endo | 0.178 |
| 1 | CA | G | 1300 | 312.3 | 47.8 | 286.6 | 78.2 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 1397 | 329.8 | 56.1 | 338.5 | 32.0 | 115.9 | 33.2 | C3'endo | 0.478 |
| 1 | CA | A | 1398 | 131.0 | 54.7 | 154.4 | 80.9 | --- | --- | C3'endo | 0.113 |
| 1 | CA | A | 1447 | 61.9 | 76.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 100 | 45.6 | 343.0 | 19.4 | 2.5 | 82.3 | 3.0 | C3'endo | 0.021 |
| 1 | DA | G | 102 | 200.0 | 55.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 154A | 119.2 | 284.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 229 | 327.5 | 348.4 | 17.0 | 341.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 248 | 122.7 | 304.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 272B | 242.0 | 132.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 352 | 264.2 | 111.8 | 243.1 | 101.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 443 | 269.2 | 82.0 | 310.5 | 63.1 | 11.5 | 16.2 | C3'endo | 0.455 |
| 1 | DA | A | 480 | 109.8 | 308.2 | --- | --- | --- | --- | C3'endo | 0.027 |
| 1 | DA | U | 504 | 322.4 | 86.1 | 324.3 | 55.8 | 334.7 | 358.8 | C3'endo | 0.415 |
| 1 | DA | G | 508 | 299.3 | 82.6 | 277.2 | 73.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 645 | 68.7 | 355.5 | 72.4 | 308.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 747 | 319.7 | 32.9 | 355.8 | 17.7 | 131.6 | 12.3 | C3'endo | 0.407 |
| 1 | DA | A | 751 | 301.4 | 100.2 | 324.6 | 117.9 | 317.5 | 122.7 | C3'endo | 0.805 |
| 1 | DA | A | 784 | 306.6 | 106.8 | 306.9 | 100.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 887 | 263.2 | 127.8 | 257.4 | 113.3 | --- | --- | C3'endo | 0.115 |
| 1 | DA | U | 958 | 292.4 | 89.1 | 350.7 | 75.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 1022 | 271.4 | 67.6 | 275.8 | 82.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1046 | 4.2 | 13.6 | 5.1 | 319.5 | --- | --- | C3'endo | 0.087 |
| 1 | DA | C | 1052 | 21.4 | 131.7 | 77.5 | 142.4 | 49.0 | 168.4 | C3'endo | 0.077 |
| 1 | DA | C | 1135 | 82.5 | 265.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 1136 | 14.9 | 164.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1177 | 241.9 | 83.4 | 261.5 | 68.4 | --- | --- | C3'endo | 0.01 |
| 1 | DA | U | 1273 | 340.7 | 137.8 | 27.2 | 113.0 | 63.2 | 90.1 | C3'endo | 0.258 |
| 1 | DA | U | 1300 | 309.0 | 73.1 | 283.7 | 63.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1420 | 9.8 | 306.7 | 70.5 | 276.3 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1497 | 89.5 | 303.6 | 92.1 | 303.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 1509 | 282.4 | 318.9 | 282.4 | 334.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1757 | 328.3 | 356.7 | 326.7 | 337.0 | 11.0 | 346.8 | C3'endo | 0.127 |
| 1 | DA | C | 1965 | 265.1 | 341.4 | 332.4 | 295.6 | --- | --- | C3'endo | 0.053 |
| 1 | DA | A | 1971 | 17.8 | 334.4 | 0.3 | 331.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1981 | 299.3 | 291.8 | --- | --- | --- | --- | C3'endo | 0.381 |
| 1 | DA | A | 2030 | 7.9 | 107.8 | 35.2 | 102.3 | 18.6 | 76.9 | C3'endo | 0.229 |
| 1 | DA | C | 2055 | 236.0 | 47.7 | 257.5 | 57.6 | 307.3 | 121.9 | C3'endo | 0.0 |
| 1 | DA | U | 2132 | 324.5 | 19.4 | 358.6 | 345.1 | --- | --- | C3'endo | 0.113 |
| 1 | DA | G | 2206 | 99.3 | 290.9 | --- | --- | --- | --- | C3'endo | 0.018 |
| 1 | DA | U | 2218 | 30.9 | 320.2 | 47.6 | 303.3 | --- | --- | C3'endo | 0.01 |
| 1 | DA | A | 2267 | 127.6 | 33.8 | 140.4 | 33.1 | --- | --- | C3'endo | 0.69 |
| 1 | DA | G | 2282 | 202.9 | 47.0 | 215.5 | 29.7 | 205.2 | 42.3 | C3'endo | 0.642 |
| 1 | DA | C | 2424 | 93.0 | 332.9 | 87.4 | 323.5 | --- | --- | C3'endo | 0.185 |
| 1 | DA | G | 2428 | 294.1 | 100.5 | 278.5 | 95.0 | --- | --- | C3'endo | 0.018 |
| 1 | DA | C | 2440 | 348.0 | 277.9 | --- | --- | --- | --- | C3'endo | 0.264 |
| 1 | DA | G | 2502 | 331.6 | 47.3 | 348.2 | 42.1 | 139.6 | 64.4 | C3'endo | 0.0 |
| 1 | DA | G | 2505 | 340.8 | 154.5 | 341.3 | 134.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 2542 | 223.8 | 105.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2689 | 101.5 | 60.7 | 123.6 | 66.0 | 164.6 | 84.5 | C3'endo | 0.0 |
| 1 | DA | A | 2712A | 86.6 | 328.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 2765 | 80.8 | 263.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2893 | 232.2 | 10.1 | 249.5 | 39.9 | --- | --- | C3'endo | 0.0 |
| 1 | DB | U | 41 | 275.6 | 329.4 | --- | --- | --- | --- | C3'endo | 0.244 |
| 1 | DB | G | 44 | 274.5 | 126.9 | 304.1 | 88.1 | 296.4 | 68.1 | C3'endo | 0.391 |
| 1 | AA | U | 90 | --- | --- | 214.7 | 24.7 | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 108 | --- | --- | 211.8 | 325.7 | --- | --- | C3'endo | 0.37 |
| 1 | AA | G | 484 | --- | --- | 120.5 | 124.0 | 118.5 | 143.4 | C3'endo | 0.0 |
| 1 | AA | A | 532 | --- | --- | 294.2 | 263.8 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 722 | --- | --- | 122.4 | 133.5 | 142.1 | 62.4 | C3'endo | 0.757 |
| 1 | AA | U | 1257 | --- | --- | 282.6 | 62.2 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1363 | --- | --- | 125.2 | 359.3 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 74 | --- | --- | 234.6 | 33.5 | 186.5 | 41.5 | C3'endo | 0.0 |
| 1 | BA | A | 412 | --- | --- | 263.2 | 263.7 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 781 | --- | --- | 348.8 | 83.6 | 347.3 | 25.4 | C3'endo | 0.624 |
| 1 | BA | G | 1173 | --- | --- | 282.2 | 277.7 | 325.0 | 327.9 | C3'endo | 0.0 |
| 1 | BA | A | 1494 | --- | --- | 155.0 | 100.1 | 158.7 | 33.2 | C3'endo | 0.0 |
| 1 | BA | C | 1531 | --- | --- | 140.4 | 294.2 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1779 | --- | --- | 154.9 | 26.4 | 129.1 | 33.9 | C3'endo | 0.49 |
| 1 | BA | G | 1992 | --- | --- | 314.1 | 102.1 | 287.9 | 78.0 | C3'endo | 0.51 |
| 1 | BA | G | 2131 | --- | --- | 132.1 | 44.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2133 | --- | --- | 227.2 | 112.8 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2207 | --- | --- | 339.4 | 124.6 | 23.3 | 34.2 | C3'endo | 0.0 |
| 1 | BA | A | 2208 | --- | --- | 88.0 | 111.4 | 108.6 | 22.8 | C3'endo | 0.0 |
| 1 | BA | C | 2573 | --- | --- | 254.8 | 63.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 2577 | --- | --- | 289.6 | 352.4 | --- | --- | C3'endo | 0.01 |
| 1 | BA | C | 2610 | --- | --- | 253.8 | 107.7 | --- | --- | C3'endo | 0.498 |
| 1 | BA | U | 2702 | --- | --- | 79.3 | 150.8 | 42.2 | 152.0 | C3'endo | 0.0 |
| 1 | BA | C | 2755 | --- | --- | 351.4 | 149.3 | 355.1 | 99.5 | C3'endo | 0.302 |
| 1 | BA | G | 2777 | --- | --- | 324.5 | 66.3 | --- | --- | C3'endo | 0.613 |
| 1 | BB | A | 13 | --- | --- | 237.8 | 146.5 | --- | --- | C3'endo | 0.407 |
| 1 | BB | A | 66 | --- | --- | 235.1 | 121.8 | --- | --- | C3'endo | 0.655 |
| 1 | CA | U | 90 | --- | --- | 214.9 | 25.0 | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 108 | --- | --- | 211.3 | 325.9 | --- | --- | C3'endo | 0.376 |
| 1 | CA | G | 484 | --- | --- | 120.1 | 123.7 | 118.0 | 143.5 | C3'endo | 0.0 |
| 1 | CA | A | 532 | --- | --- | 294.5 | 262.9 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 722 | --- | --- | 122.6 | 133.6 | 142.4 | 62.6 | C3'endo | 0.764 |
| 1 | CA | U | 1257 | --- | --- | 282.7 | 62.2 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 1363 | --- | --- | 124.5 | 359.8 | --- | --- | C3'endo | 0.0 |
| 1 | CW | A | 21 | --- | --- | 282.2 | 162.0 | --- | --- | C3'endo | 0.0 |
| 1 | CY | A | 21 | --- | --- | 282.6 | 169.1 | 296.7 | 144.4 | C3'endo | 0.0 |
| 1 | DA | A | 74 | --- | --- | 233.8 | 33.0 | 185.9 | 40.7 | C3'endo | 0.0 |
| 1 | DA | A | 412 | --- | --- | 262.5 | 263.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 781 | --- | --- | 348.8 | 83.0 | 346.8 | 25.2 | C3'endo | 0.621 |
| 1 | DA | G | 1173 | --- | --- | 282.4 | 277.7 | 325.2 | 327.8 | C3'endo | 0.0 |
| 1 | DA | A | 1494 | --- | --- | 154.6 | 100.1 | 158.4 | 33.2 | C3'endo | 0.0 |
| 1 | DA | C | 1531 | --- | --- | 140.6 | 294.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1779 | --- | --- | 155.0 | 27.3 | 128.0 | 34.6 | C3'endo | 0.484 |
| 1 | DA | A | 1785 | --- | --- | 112.2 | 146.9 | 120.3 | 89.7 | C3'endo | 0.477 |
| 1 | DA | G | 1992 | --- | --- | 314.0 | 102.3 | 288.0 | 78.0 | C3'endo | 0.479 |
| 1 | DA | G | 2131 | --- | --- | 132.5 | 44.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2133 | --- | --- | 227.7 | 113.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2207 | --- | --- | 339.2 | 124.8 | 23.4 | 34.2 | C3'endo | 0.0 |
| 1 | DA | A | 2208 | --- | --- | 88.1 | 111.7 | 108.7 | 23.0 | C3'endo | 0.0 |
| 1 | DA | C | 2573 | --- | --- | 254.3 | 61.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 2577 | --- | --- | 289.5 | 353.2 | --- | --- | C3'endo | 0.01 |
| 1 | DA | C | 2610 | --- | --- | 253.7 | 107.0 | --- | --- | C3'endo | 0.485 |
| 1 | DA | U | 2702 | --- | --- | 79.2 | 150.6 | 42.4 | 151.9 | C3'endo | 0.0 |
| 1 | DA | C | 2755 | --- | --- | 351.7 | 148.7 | 354.8 | 98.7 | C3'endo | 0.321 |
| 1 | DA | G | 2777 | --- | --- | 324.1 | 66.3 | --- | --- | C3'endo | 0.595 |
| 1 | DB | A | 13 | --- | --- | 237.8 | 146.7 | --- | --- | C3'endo | 0.44 |
| 1 | DB | A | 66 | --- | --- | 235.3 | 121.8 | --- | --- | C3'endo | 0.653 |
| 1 | AA | G | 6 | --- | --- | --- | --- | 130.6 | 109.5 | C3'endo | 0.109 |
| 1 | AA | U | 81 | --- | --- | --- | --- | 140.3 | 110.1 | C3'endo | 0.0 |
| 1 | AA | A | 665 | --- | --- | --- | --- | 14.8 | 156.4 | C3'endo | 0.0 |
| 1 | AA | A | 977 | --- | --- | --- | --- | 73.7 | 178.8 | C3'endo | 0.0 |
| 1 | AA | C | 1027 | --- | --- | --- | --- | 296.3 | 176.3 | C3'endo | 0.165 |
| 1 | AA | A | 1183 | 5.8 | 292.0 | --- | --- | 34.6 | 192.9 | C3'endo | 0.271 |
| 1 | AW | A | 21 | --- | --- | --- | --- | 298.5 | 156.1 | C3'endo | 0.0 |
| 1 | BA | U | 158 | --- | --- | --- | --- | 181.9 | 28.5 | C3'endo | 0.0 |
| 1 | BA | A | 221 | 214.9 | 37.8 | --- | --- | 160.8 | 80.4 | C3'endo | 0.0 |
| 1 | BA | U | 271L | --- | --- | --- | --- | 197.0 | 60.3 | C3'endo | 0.0 |
| 1 | BA | G | 388 | --- | --- | --- | --- | 73.8 | 141.9 | C3'endo | 0.0 |
| 1 | BA | C | 587 | 212.8 | 75.6 | --- | --- | 178.3 | 93.3 | C3'endo | 0.236 |
| 1 | BA | G | 614B | --- | --- | --- | --- | 288.6 | 114.2 | C3'endo | 0.0 |
| 1 | BA | G | 763 | --- | --- | --- | --- | 104.9 | 116.6 | C3'endo | 0.569 |
| 1 | BA | U | 827 | 352.0 | 44.6 | --- | --- | 334.1 | 53.7 | C3'endo | 0.0 |
| 1 | BA | C | 886 | --- | --- | --- | --- | 95.2 | 182.5 | C3'endo | 0.0 |
| 1 | BA | U | 1033 | --- | --- | --- | --- | 3.0 | 146.3 | C3'endo | 0.01 |
| 1 | BA | C | 1043 | --- | --- | --- | --- | 307.6 | 119.4 | C3'endo | 0.0 |
| 1 | BA | A | 1127 | --- | --- | --- | --- | 96.3 | 134.8 | C3'endo | 0.014 |
| 1 | BA | A | 1210 | --- | --- | --- | --- | 144.3 | 335.6 | C3'endo | 0.0 |
| 1 | BA | A | 1274 | --- | --- | --- | --- | 350.1 | 134.3 | C3'endo | 0.354 |
| 1 | BA | A | 1700 | --- | --- | --- | --- | 343.4 | 296.5 | C3'endo | 0.0 |
| 1 | BA | A | 1785 | --- | --- | --- | --- | 120.8 | 89.9 | C3'endo | 0.419 |
| 1 | BA | G | 1816 | 311.7 | 16.2 | --- | --- | 291.7 | 80.1 | C3'endo | 0.0 |
| 1 | BA | G | 2307 | --- | --- | --- | --- | 304.0 | 190.1 | C3'endo | 0.0 |
| 1 | BA | G | 2308 | 283.6 | 306.3 | --- | --- | 34.8 | 132.8 | C3'endo | 0.0 |
| 1 | BA | A | 2309 | --- | --- | --- | --- | 40.7 | 153.8 | C3'endo | 0.0 |
| 1 | BA | G | 2405 | --- | --- | --- | --- | 278.0 | 67.3 | C3'endo | 0.434 |
| 1 | BA | U | 2438 | --- | --- | --- | --- | 199.7 | 30.9 | C3'endo | 0.656 |
| 1 | BA | A | 2476 | --- | --- | --- | --- | 0.7 | 155.4 | C3'endo | 0.0 |
| 1 | BA | U | 2688 | --- | --- | --- | --- | 263.9 | 2.5 | C3'endo | 0.753 |
| 1 | BA | G | 2872 | --- | --- | --- | --- | 80.5 | 126.3 | C3'endo | 0.0 |
| 1 | BA | A | 2883 | --- | --- | --- | --- | 155.0 | 342.2 | C3'endo | 0.528 |
| 1 | CA | G | 6 | --- | --- | --- | --- | 130.8 | 110.1 | C3'endo | 0.108 |
| 1 | CA | U | 81 | --- | --- | --- | --- | 140.4 | 110.3 | C3'endo | 0.0 |
| 1 | CA | A | 665 | --- | --- | --- | --- | 14.5 | 155.8 | C3'endo | 0.0 |
| 1 | CA | A | 977 | --- | --- | --- | --- | 73.5 | 178.8 | C3'endo | 0.0 |
| 1 | CA | C | 1027 | --- | --- | --- | --- | 296.2 | 176.1 | C3'endo | 0.166 |
| 1 | CA | A | 1183 | 5.4 | 291.7 | --- | --- | 34.4 | 192.9 | C3'endo | 0.291 |
| 1 | CA | A | 1492 | --- | --- | --- | --- | 37.2 | 188.7 | C3'endo | 0.0 |
| 1 | CV | A | 21 | --- | --- | --- | --- | 305.4 | 178.7 | C3'endo | 0.0 |
| 1 | DA | U | 158 | --- | --- | --- | --- | 181.8 | 28.5 | C3'endo | 0.0 |
| 1 | DA | A | 221 | 215.0 | 38.9 | --- | --- | 160.5 | 80.7 | C3'endo | 0.0 |
| 1 | DA | U | 271L | --- | --- | --- | --- | 197.9 | 60.7 | C3'endo | 0.0 |
| 1 | DA | G | 388 | --- | --- | --- | --- | 73.9 | 141.7 | C3'endo | 0.0 |
| 1 | DA | C | 587 | 212.1 | 76.2 | --- | --- | 178.3 | 93.5 | C3'endo | 0.263 |
| 1 | DA | G | 614B | --- | --- | --- | --- | 289.0 | 114.8 | C3'endo | 0.0 |
| 1 | DA | G | 763 | --- | --- | --- | --- | 105.2 | 116.3 | C3'endo | 0.585 |
| 1 | DA | U | 827 | 350.8 | 45.3 | --- | --- | 333.5 | 54.3 | C3'endo | 0.0 |
| 1 | DA | C | 886 | --- | --- | --- | --- | 95.1 | 182.5 | C3'endo | 0.0 |
| 1 | DA | U | 1033 | --- | --- | --- | --- | 3.0 | 146.7 | C3'endo | 0.01 |
| 1 | DA | C | 1043 | --- | --- | --- | --- | 307.6 | 119.4 | C3'endo | 0.0 |
| 1 | DA | A | 1127 | --- | --- | --- | --- | 96.0 | 134.6 | C3'endo | 0.013 |
| 1 | DA | A | 1210 | 199.0 | 53.3 | --- | --- | 144.1 | 335.8 | C3'endo | 0.0 |
| 1 | DA | A | 1274 | --- | --- | --- | --- | 350.8 | 134.2 | C3'endo | 0.309 |
| 1 | DA | A | 1700 | --- | --- | --- | --- | 343.3 | 297.2 | C3'endo | 0.0 |
| 1 | DA | G | 1816 | 313.0 | 14.4 | --- | --- | 292.3 | 80.0 | C3'endo | 0.0 |
| 1 | DA | G | 2307 | --- | --- | --- | --- | 304.3 | 190.3 | C3'endo | 0.0 |
| 1 | DA | G | 2308 | 286.1 | 304.6 | --- | --- | 34.6 | 132.7 | C3'endo | 0.0 |
| 1 | DA | A | 2309 | --- | --- | --- | --- | 40.5 | 153.8 | C3'endo | 0.0 |
| 1 | DA | G | 2405 | --- | --- | --- | --- | 277.0 | 67.0 | C3'endo | 0.459 |
| 1 | DA | U | 2438 | --- | --- | --- | --- | 198.2 | 30.6 | C3'endo | 0.685 |
| 1 | DA | A | 2476 | --- | --- | --- | --- | 0.7 | 155.6 | C3'endo | 0.0 |
| 1 | DA | U | 2688 | --- | --- | --- | --- | 264.1 | 2.8 | C3'endo | 0.787 |
| 1 | DA | G | 2872 | --- | --- | --- | --- | 80.3 | 126.1 | C3'endo | 0.0 |
| 1 | DA | A | 2883 | --- | --- | --- | --- | 155.0 | 342.7 | C3'endo | 0.542 |
| 1 | AA | A | 51 | 25.9 | 55.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 130 | 341.3 | 250.5 | --- | --- | --- | --- | C2'endo | 0.694 |
| 1 | AA | G | 189G | 353.6 | 48.5 | 104.1 | 354.0 | --- | --- | C2'endo | 0.019 |
| 1 | AA | A | 344 | 73.0 | 352.4 | --- | --- | --- | --- | C2'endo | 0.277 |
| 1 | AA | A | 461 | 14.8 | 248.5 | 66.8 | 188.9 | 32.5 | 149.2 | C2'endo | 0.01 |
| 1 | AA | A | 533 | 228.4 | 336.5 | 327.1 | 242.5 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 815 | 67.1 | 25.7 | 55.8 | 2.6 | --- | --- | C2'endo | 0.091 |
| 1 | AA | A | 974 | 83.7 | 57.8 | 118.8 | 33.7 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 975 | 37.6 | 69.2 | 40.7 | 66.2 | 62.0 | 68.9 | C2'endo | 0.0 |
| 1 | AA | G | 1064 | 14.8 | 182.9 | --- | --- | --- | --- | C2'endo | 0.066 |
| 1 | AA | G | 1094 | 18.8 | 63.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AV | A | 7 | 167.3 | 353.8 | --- | --- | --- | --- | C2'endo | 0.525 |
| 1 | AV | G | 18 | 302.3 | 214.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AV | G | 46 | 273.6 | 258.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AW | G | 18 | 305.4 | 221.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AW | G | 19 | 257.2 | 291.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AY | C | 56 | 66.2 | 231.6 | 66.4 | 227.7 | --- | --- | C2'endo | 0.067 |
| 1 | BA | U | 99 | 187.0 | 34.4 | --- | --- | --- | --- | C2'endo | 0.123 |
| 1 | BA | U | 271K | 21.8 | 9.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 330 | 88.9 | 233.5 | 140.8 | 197.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 386 | 112.2 | 329.9 | 118.4 | 315.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 457 | 347.8 | 184.0 | 5.5 | 151.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 532 | 155.5 | 26.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 562 | 281.8 | 162.4 | --- | --- | --- | --- | C2'endo | 0.362 |
| 1 | BA | G | 573 | 246.6 | 195.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 574 | 35.5 | 79.3 | 66.8 | 55.2 | --- | --- | C2'endo | 0.292 |
| 1 | BA | A | 627 | 306.8 | 190.1 | 41.5 | 156.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 945 | 93.9 | 227.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 974 | 71.1 | 15.5 | 114.4 | 357.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 975 | 67.4 | 14.0 | 59.8 | 17.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1025 | 32.1 | 55.8 | 101.9 | 19.0 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1048 | 260.1 | 182.2 | 278.7 | 120.7 | --- | --- | C2'endo | 0.01 |
| 1 | BA | A | 1126 | 81.5 | 92.9 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | U | 1175 | 118.3 | 93.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1176 | 96.6 | 239.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1252 | 0.3 | 234.1 | 37.9 | 207.8 | --- | --- | C2'endo | 0.371 |
| 1 | BA | A | 1265 | 87.3 | 133.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1272 | 290.1 | 228.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1416 | 321.5 | 121.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1453 | 43.9 | 203.1 | --- | --- | --- | --- | C2'endo | 0.309 |
| 1 | BA | C | 1530 | 120.4 | 206.5 | 135.2 | 197.0 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1722 | 18.9 | 253.8 | 77.1 | 190.1 | 27.7 | 99.1 | C2'endo | 0.0 |
| 1 | BA | G | 1758 | 247.0 | 281.4 | --- | --- | --- | --- | C2'endo | 0.382 |
| 1 | BA | G | 1930 | 150.8 | 58.0 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | A | 1938 | 13.8 | 253.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1963 | 25.2 | 215.9 | 41.9 | 184.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2031 | 117.0 | 71.3 | 129.4 | 4.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2225 | 283.8 | 358.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2266 | 61.8 | 76.1 | --- | --- | --- | --- | C2'endo | 0.703 |
| 1 | BA | A | 2311 | 251.3 | 264.2 | 287.7 | 259.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2425 | 109.3 | 64.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 2585 | 99.0 | 137.9 | --- | --- | --- | --- | C2'endo | 0.045 |
| 1 | BA | A | 2602 | 72.2 | 27.3 | 40.6 | 29.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2713 | 57.2 | 242.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 2867 | 348.6 | 38.1 | --- | --- | --- | --- | C2'endo | 0.047 |
| 1 | CA | A | 51 | 25.9 | 56.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 130 | 341.2 | 250.5 | --- | --- | --- | --- | C2'endo | 0.691 |
| 1 | CA | G | 189G | 352.8 | 48.6 | 103.7 | 353.7 | --- | --- | C2'endo | 0.017 |
| 1 | CA | A | 344 | 73.8 | 352.3 | --- | --- | --- | --- | C2'endo | 0.269 |
| 1 | CA | A | 461 | 14.7 | 248.1 | 66.6 | 188.8 | 32.3 | 149.2 | C2'endo | 0.01 |
| 1 | CA | A | 533 | 229.0 | 335.9 | 328.1 | 242.0 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 815 | 67.3 | 25.8 | 56.2 | 2.1 | --- | --- | C2'endo | 0.063 |
| 1 | CA | A | 974 | 82.8 | 58.4 | 118.4 | 34.0 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 975 | 37.3 | 69.2 | 40.5 | 66.3 | 62.1 | 69.1 | C2'endo | 0.0 |
| 1 | CA | G | 1064 | 14.4 | 183.3 | --- | --- | --- | --- | C2'endo | 0.064 |
| 1 | CA | G | 1094 | 18.2 | 63.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 1452 | 80.6 | 99.6 | 155.7 | 42.4 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1502 | 146.6 | 288.6 | --- | --- | --- | --- | C2'endo | 0.08 |
| 1 | CV | G | 18 | 299.2 | 216.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CV | G | 19 | 239.0 | 344.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CV | G | 46 | 276.4 | 257.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CW | G | 18 | 322.3 | 214.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CW | G | 19 | 257.7 | 273.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CY | G | 18 | 337.9 | 255.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CY | C | 56 | 55.3 | 243.9 | 64.0 | 238.7 | --- | --- | C2'endo | 0.123 |
| 1 | DA | U | 99 | 187.2 | 33.7 | --- | --- | --- | --- | C2'endo | 0.136 |
| 1 | DA | A | 322 | 161.8 | 337.6 | --- | --- | --- | --- | C2'endo | 0.19 |
| 1 | DA | A | 330 | 89.8 | 233.4 | 141.3 | 197.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 386 | 110.9 | 330.8 | 117.7 | 316.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 457 | 348.0 | 184.2 | 6.4 | 151.6 | 327.4 | 154.5 | C2'endo | 0.0 |
| 1 | DA | A | 532 | 155.0 | 26.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 562 | 282.1 | 161.7 | --- | --- | --- | --- | C2'endo | 0.335 |
| 1 | DA | G | 573 | 245.6 | 195.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 574 | 36.2 | 79.9 | 66.9 | 56.6 | --- | --- | C2'endo | 0.31 |
| 1 | DA | A | 627 | 307.8 | 189.4 | 41.9 | 156.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 945 | 94.2 | 229.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 974 | 70.4 | 16.0 | 114.1 | 358.2 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 975 | 67.2 | 14.1 | 59.6 | 17.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1025 | 32.3 | 55.8 | 101.6 | 19.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1048 | 260.4 | 181.4 | 278.7 | 120.7 | --- | --- | C2'endo | 0.01 |
| 1 | DA | A | 1126 | 81.7 | 92.7 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DA | U | 1175 | 118.4 | 92.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1176 | 96.6 | 239.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1252 | 0.1 | 234.5 | 38.2 | 207.8 | --- | --- | C2'endo | 0.397 |
| 1 | DA | A | 1272 | 290.1 | 228.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1416 | 322.0 | 120.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1453 | 42.8 | 203.4 | --- | --- | --- | --- | C2'endo | 0.316 |
| 1 | DA | C | 1530 | 120.2 | 206.5 | 135.0 | 197.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1722 | 18.5 | 253.9 | 77.2 | 190.0 | 27.7 | 99.2 | C2'endo | 0.0 |
| 1 | DA | G | 1758 | 247.5 | 280.9 | --- | --- | --- | --- | C2'endo | 0.378 |
| 1 | DA | G | 1930 | 149.7 | 57.7 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DA | A | 1938 | 14.1 | 254.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1963 | 24.5 | 215.2 | 41.4 | 184.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2031 | 116.1 | 72.0 | 128.7 | 6.3 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2225 | 283.9 | 358.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2266 | 61.6 | 76.3 | --- | --- | --- | --- | C2'endo | 0.698 |
| 1 | DA | A | 2311 | 252.9 | 265.7 | 289.3 | 259.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2425 | 109.6 | 65.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2585 | 97.9 | 137.6 | --- | --- | --- | --- | C2'endo | 0.025 |
| 1 | DA | A | 2602 | 72.4 | 26.7 | 40.6 | 28.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2713 | 57.4 | 242.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 2867 | 348.3 | 38.6 | --- | --- | --- | --- | C2'endo | 0.071 |
| 1 | AA | A | 8 | --- | --- | 287.9 | 243.0 | 308.6 | 260.2 | C2'endo | 0.291 |
| 1 | AA | A | 50 | --- | --- | 75.3 | 87.7 | --- | --- | C2'endo | 0.172 |
| 1 | AA | A | 60 | --- | --- | 22.0 | 137.6 | --- | --- | C2'endo | 0.054 |
| 1 | AA | A | 109 | --- | --- | 136.8 | 301.4 | --- | --- | C2'endo | 0.55 |
| 1 | AA | U | 189F | --- | --- | 320.1 | 246.8 | 309.7 | 219.8 | C2'endo | 0.04 |
| 1 | AA | A | 451 | --- | --- | 81.0 | 108.7 | --- | --- | C2'endo | 0.375 |
| 1 | AA | A | 496 | --- | --- | 152.6 | 207.2 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 1196 | --- | --- | 309.0 | 19.3 | 322.5 | 113.5 | C2'endo | 0.0 |
| 1 | AA | A | 1201 | --- | --- | 39.1 | 87.3 | 91.7 | 82.6 | C2'endo | 0.0 |
| 1 | AA | A | 1363A | --- | --- | 68.3 | 63.2 | --- | --- | C2'endo | 0.0 |
| 1 | AW | C | 17 | --- | --- | 12.4 | 15.9 | 26.7 | 173.4 | C2'endo | 0.0 |
| 1 | AY | A | 7 | --- | --- | 242.1 | 318.5 | 274.2 | 349.2 | C2'endo | 0.654 |
| 1 | AY | C | 17 | --- | --- | 45.6 | 150.9 | 28.4 | 184.0 | C2'endo | 0.0 |
| 1 | BA | A | 196 | --- | --- | 329.7 | 245.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 265 | --- | --- | 75.8 | 156.4 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 271O | --- | --- | 169.8 | 188.0 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 530 | --- | --- | 154.8 | 192.4 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 548 | --- | --- | 302.8 | 357.5 | 274.5 | 22.1 | C2'endo | 0.0 |
| 1 | BA | G | 1325 | --- | --- | 340.4 | 248.3 | --- | --- | C2'endo | 0.245 |
| 1 | BA | A | 1913 | --- | --- | 66.1 | 84.8 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 8 | --- | --- | 289.3 | 243.0 | 309.7 | 259.9 | C2'endo | 0.254 |
| 1 | CA | A | 50 | --- | --- | 75.5 | 87.2 | --- | --- | C2'endo | 0.191 |
| 1 | CA | A | 60 | --- | --- | 21.6 | 138.0 | --- | --- | C2'endo | 0.056 |
| 1 | CA | A | 109 | --- | --- | 136.1 | 300.7 | --- | --- | C2'endo | 0.528 |
| 1 | CA | U | 189F | --- | --- | 320.6 | 247.3 | 309.8 | 219.7 | C2'endo | 0.036 |
| 1 | CA | A | 451 | --- | --- | 80.8 | 108.7 | --- | --- | C2'endo | 0.379 |
| 1 | CA | A | 496 | --- | --- | 152.7 | 207.4 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1196 | --- | --- | 309.3 | 18.7 | 322.9 | 113.5 | C2'endo | 0.0 |
| 1 | CA | A | 1201 | --- | --- | 38.8 | 87.4 | 92.0 | 82.5 | C2'endo | 0.0 |
| 1 | CA | A | 1363A | --- | --- | 67.3 | 63.5 | --- | --- | C2'endo | 0.0 |
| 1 | CV | C | 48 | --- | --- | 318.7 | 28.1 | --- | --- | C2'endo | 0.0 |
| 1 | CW | C | 48 | --- | --- | 8.4 | 18.6 | --- | --- | C2'endo | 0.112 |
| 1 | CY | C | 17 | --- | --- | 25.3 | 147.0 | 19.2 | 183.3 | C2'endo | 0.0 |
| 1 | DA | A | 196 | --- | --- | 329.9 | 245.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 265 | --- | --- | 76.1 | 156.2 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 271O | --- | --- | 169.3 | 188.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 530 | --- | --- | 154.9 | 192.2 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 548 | --- | --- | 302.8 | 357.5 | 274.4 | 22.3 | C2'endo | 0.0 |
| 1 | DA | G | 1325 | --- | --- | 340.3 | 247.9 | --- | --- | C2'endo | 0.239 |
| 1 | DA | A | 1913 | --- | --- | 65.9 | 85.0 | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 129A | --- | --- | --- | --- | 39.9 | 18.5 | C2'endo | 0.037 |
| 1 | AA | U | 561 | --- | --- | --- | --- | 63.5 | 116.8 | C2'endo | 0.0 |
| 1 | AA | A | 1157 | --- | --- | --- | --- | 70.0 | 75.8 | C2'endo | 0.214 |
| 1 | AV | U | 47 | 292.6 | 302.0 | --- | --- | 10.7 | 206.2 | C2'endo | 0.0 |
| 1 | AW | U | 47 | 300.7 | 293.7 | --- | --- | 8.0 | 213.9 | C2'endo | 0.0 |
| 1 | AY | U | 47 | 290.7 | 13.5 | --- | --- | 320.3 | 122.8 | C2'endo | 0.0 |
| 1 | BA | G | 321 | --- | --- | --- | --- | 341.0 | 296.1 | C2'endo | 0.373 |
| 1 | BA | G | 323 | 92.5 | 56.3 | --- | --- | 161.6 | 27.6 | C2'endo | 0.457 |
| 1 | BA | C | 456 | --- | --- | --- | --- | 49.0 | 147.2 | C2'endo | 0.0 |
| 1 | BA | U | 1205 | --- | --- | --- | --- | 330.7 | 21.7 | C2'endo | 0.0 |
| 1 | BA | C | 1428 | --- | --- | --- | --- | 148.0 | 287.8 | C2'endo | 0.0 |
| 1 | BA | A | 1460 | --- | --- | --- | --- | 347.8 | 332.4 | C2'endo | 0.0 |
| 1 | BA | A | 1558 | --- | --- | --- | --- | 97.2 | 43.4 | C2'endo | 0.0 |
| 1 | BA | G | 1674 | --- | --- | --- | --- | 332.4 | 95.2 | C2'endo | 0.0 |
| 1 | BA | A | 1698 | --- | --- | --- | --- | 95.7 | 82.6 | C2'endo | 0.01 |
| 1 | BA | U | 1739 | --- | --- | --- | --- | 47.6 | 193.2 | C2'endo | 0.0 |
| 1 | BA | A | 1900 | --- | --- | --- | --- | 295.3 | 18.0 | C2'endo | 0.0 |
| 1 | BA | U | 2092 | --- | --- | --- | --- | 81.0 | 115.5 | C2'endo | 0.693 |
| 1 | BA | U | 2118 | 327.6 | 251.5 | --- | --- | 35.1 | 205.3 | C2'endo | 0.0 |
| 1 | BA | U | 2249 | --- | --- | --- | --- | 301.7 | 245.5 | C2'endo | 0.622 |
| 1 | BA | G | 2345 | --- | --- | --- | --- | 23.1 | 108.8 | C2'endo | 0.0 |
| 1 | BA | A | 2346 | 347.1 | 25.7 | --- | --- | 317.1 | 348.5 | C2'endo | 0.21 |
| 1 | BA | A | 2439 | --- | --- | --- | --- | 60.2 | 35.1 | C2'endo | 0.0 |
| 1 | BA | U | 2712 | 343.5 | 197.5 | --- | --- | 97.8 | 102.8 | C2'endo | 0.0 |
| 1 | BA | A | 2753 | --- | --- | --- | --- | 258.0 | 242.8 | C2'endo | 0.118 |
| 1 | BA | C | 2791 | 141.2 | 96.2 | --- | --- | 71.4 | 109.0 | C2'endo | 0.01 |
| 1 | BA | U | 2866 | --- | --- | --- | --- | 42.3 | 149.6 | C2'endo | 0.567 |
| 1 | CA | G | 129A | --- | --- | --- | --- | 39.6 | 18.3 | C2'endo | 0.036 |
| 1 | CA | U | 561 | --- | --- | --- | --- | 63.7 | 116.3 | C2'endo | 0.0 |
| 1 | CA | A | 1157 | --- | --- | --- | --- | 70.1 | 75.7 | C2'endo | 0.219 |
| 1 | CV | U | 47 | 296.2 | 303.1 | --- | --- | 7.2 | 196.8 | C2'endo | 0.0 |
| 1 | CW | C | 17 | --- | --- | --- | --- | 30.2 | 180.8 | C2'endo | 0.0 |
| 1 | CW | U | 47 | --- | --- | --- | --- | 14.9 | 208.6 | C2'endo | 0.0 |
| 1 | DA | G | 321 | --- | --- | --- | --- | 340.4 | 296.7 | C2'endo | 0.388 |
| 1 | DA | G | 323 | 92.3 | 56.6 | --- | --- | 161.9 | 28.2 | C2'endo | 0.448 |
| 1 | DA | C | 456 | --- | --- | --- | --- | 48.9 | 140.9 | C2'endo | 0.0 |
| 1 | DA | U | 1205 | --- | --- | --- | --- | 331.1 | 21.9 | C2'endo | 0.0 |
| 1 | DA | C | 1428 | --- | --- | --- | --- | 148.3 | 288.8 | C2'endo | 0.0 |
| 1 | DA | A | 1460 | --- | --- | --- | --- | 347.6 | 333.0 | C2'endo | 0.0 |
| 1 | DA | A | 1558 | --- | --- | --- | --- | 96.7 | 43.7 | C2'endo | 0.0 |
| 1 | DA | G | 1674 | --- | --- | --- | --- | 332.6 | 95.7 | C2'endo | 0.0 |
| 1 | DA | A | 1698 | --- | --- | --- | --- | 95.6 | 81.7 | C2'endo | 0.01 |
| 1 | DA | U | 1739 | --- | --- | --- | --- | 47.6 | 193.4 | C2'endo | 0.0 |
| 1 | DA | A | 1900 | --- | --- | --- | --- | 293.5 | 19.1 | C2'endo | 0.0 |
| 1 | DA | U | 2092 | --- | --- | --- | --- | 79.9 | 115.3 | C2'endo | 0.709 |
| 1 | DA | U | 2118 | 327.1 | 252.0 | --- | --- | 35.4 | 205.8 | C2'endo | 0.0 |
| 1 | DA | U | 2249 | --- | --- | --- | --- | 301.5 | 244.7 | C2'endo | 0.63 |
| 1 | DA | G | 2345 | --- | --- | --- | --- | 23.0 | 111.8 | C2'endo | 0.0 |
| 1 | DA | A | 2346 | 345.8 | 27.1 | --- | --- | 314.2 | 349.6 | C2'endo | 0.247 |
| 1 | DA | U | 2712 | 344.8 | 196.2 | --- | --- | 97.7 | 103.2 | C2'endo | 0.0 |
| 1 | DA | A | 2753 | --- | --- | --- | --- | 257.7 | 242.4 | C2'endo | 0.108 |
| 1 | DA | C | 2791 | --- | --- | --- | --- | 71.8 | 109.3 | C2'endo | 0.01 |
| 1 | DA | U | 2866 | --- | --- | --- | --- | 41.3 | 149.2 | C2'endo | 0.601 |