EMDataResource Pseudotorsion Plot Beta Server
RNA adopts complex three-dimensional folding patterns and has key roles in many cellular functions. Many cryoEM-derived structures contain RNA, including ribosomal particles, spliceosomes, RNA viruses, and polymerase complexes, yet procedures for validation of RNA structures are not as well developed as those for proteins.
This prototype web-service for virtual torsion angle validation of RNA structures can be applied to structures determined using cryo-EM as well as other structural methods. Virtual torsion angle plots for nucleic acids are analogous to Ramachandran plots for proteins. The tool evaluates single structures, either by file upload (mmCIF or PDB format) or by entering a PDB id.
The research community has developed simplified ways to represent nucleic acid backbone conformation through use of virtual torsion angles1-3. A common scheme is to define two virtual torsion angles (pseudotorsions), eta (η) and theta (θ) for a nucleotide triplet. The measured (η,θ) pair defines the backbone conformation relative to central residue (i).
The server calculates three varieties of pseudotorsion angles, as shown in the image below. In all definitions, phosphate atom positions are used, but the alternate atom differs: it is either the C4' atom (η,θ), C1' atom (η',θ'), or base origin4,5 position (η",θ").
Virtual torsion angles of the RNA backbone (calculated using DSSR4) are compared against the statistical distribution of a benchmark set of high quality, non-redundant6 RNA structures determined by X-ray crystallography at ≤ 2.5 Å. Separate analyses are performed based on sugar-puckering type (of ~27,000 residues in the benchmark set, ~24,000 are C3'-endo-like, ~3,000 are C2'-endo-like). Output plots and and a downloadable (csv format) table identify probable conformational outliers for any given RNA-containing structure. For comparison, RNA Suiteness7,8 scores are also provided in the csv (for residue i, suiteness of the i-1, i dinucleotide is listed. Suiteness range is 0(poor)-1(excellent). Calculation performed using DSSR).
The 2D plots permit comparison of pseudotorsion pairs for the structure being evaluated (plotted points) against population statistics of the benchmark set (smoothed contours: bar at right indicates benchmark residue count range). Outliers are marked on the plots by red crosses with residue information available on mouse hover. Summary statistics are provided below each plot to indicate the number of residues evaluated and percent outliers. Note that pseudotorsion angles cannot be calculated for terminal residues or around breaks in the polymer chain, so these are excluded from evaluation.
This tool is designed to identify regions of unusual conformation in folded RNA. Outliers can be legitimate but less-common backbone conformations, or they may indicate modelling error.
It may take several minutes to complete calculations for large structures such as ribosomes.
Please direct any questions/suggestions to help@emdataresource.org
- Olson, W. K. Configurational statistics of polynucleotide chains. An updated virtual bond model to treat effects of base stacking. Macromolecules 13, 721-728 (1980).
- Wadley, L. M., Keating, K. S., Duarte, C. M. & Pyle, A. M. Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol 372, 942-957, doi (2007).
- Keating, K. S., Humphris, E. L. & Pyle, A. M. A new way to see RNA. Q Rev Biophys 44, 433-466, doi (2011).
- Lu, X. J., Bussemaker, H. J. & Olson, W. K. DSSR: an integrated software tool for dissecting the spatial structure of RNA. Nucleic Acids Res 43, e142, doi (2015).
- Li, S., Olson, W. K., Lu, X. J. Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures. Nucleic Acids Research 47, W26-W34 (2019). doi
- Leontis, N. B., & Zirbel, C. L. Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking. In RNA 3D Structure Analysis and Prediction, N. Leontis & E. Westhof (Eds.), (Vol. 27, pp. 281-298). Springer Berlin Heidelberg. doi (2012).
- Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R.M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., Berman, H. M. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA 14, 465-81, doi (2008).
- Chen, V. B., Arendall III, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., Richardson, D. C., MolProbity: all-atom structure validation for macromolecular crystallography, Acta Cryst D 66, 12-21, doi (2010)
RNA Pseudotorsion Plots for PDB entry 4v5j
Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights into catalysis of peptide release Deposited 2010-03-24 X-RAY DIFFRACTION resol 3.1 Å
8103 C3'-endo RNA residues with 184 outliers ( 2.27 % ) from Eta-Theta plot
1199 C2'-endo RNA residues with 115 outliers ( 9.59 % ) from Eta-Theta plot
8103 C3'-endo RNA residues with 179 outliers ( 2.21 % ) from Eta'-Theta' plot
1199 C2'-endo RNA residues with 88 outliers ( 7.34 % ) from Eta'-Theta' plot
8103 C3'-endo RNA residues with 155 outliers ( 1.91 % ) from Eta"-Theta" plot
1199 C2'-endo RNA residues with 82 outliers ( 6.84 % ) from Eta"-Theta" plot
List of Outliers
| Model Number | Chain | Residue Type | Residue Identifier | Eta | Theta | Eta' | Theta' | Eta'' | Theta'' | Sugar Pucker | Suiteness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | AA | U | 30 | 216.7 | 302.8 | --- | --- | --- | --- | C3'endo | 0.352 |
| 1 | AA | C | 89 | 121.1 | 353.6 | 147.8 | 349.5 | 180.6 | 4.1 | C3'endo | 0.0 |
| 1 | AA | A | 119 | 221.4 | 73.4 | 229.6 | 67.2 | --- | --- | C3'endo | 0.854 |
| 1 | AA | A | 243 | 224.0 | 117.0 | 229.5 | 79.9 | --- | --- | C3'endo | 0.8 |
| 1 | AA | G | 247 | 264.9 | 135.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 250 | 224.5 | 131.5 | --- | --- | --- | --- | C3'endo | 0.283 |
| 1 | AA | G | 266 | 330.0 | 123.4 | 344.3 | 86.4 | 313.3 | 53.5 | C3'endo | 0.0 |
| 1 | AA | C | 352 | 76.6 | 96.3 | 76.7 | 65.4 | 94.0 | 345.7 | C3'endo | 0.0 |
| 1 | AA | A | 353 | 10.5 | 115.6 | 5.5 | 119.5 | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 530 | 208.1 | 59.5 | --- | --- | --- | --- | C3'endo | 0.681 |
| 1 | AA | A | 563 | 109.3 | 104.1 | 104.4 | 81.8 | 108.1 | 29.1 | C3'endo | 0.371 |
| 1 | AA | U | 723 | 52.3 | 293.9 | 60.3 | 298.1 | --- | --- | C3'endo | 0.284 |
| 1 | AA | C | 754 | 116.1 | 312.7 | 103.9 | 316.9 | --- | --- | C3'endo | 0.659 |
| 1 | AA | A | 816 | 71.4 | 30.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 839 | 79.9 | 17.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 841 | 332.6 | 316.4 | 334.7 | 319.5 | 10.1 | 348.1 | C3'endo | 0.0 |
| 1 | AA | U | 992 | 320.3 | 96.1 | 292.4 | 80.6 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 1004 | 210.6 | 126.5 | --- | --- | --- | --- | C3'endo | 0.054 |
| 1 | AA | A | 1005 | 261.8 | 281.1 | 249.0 | 287.3 | --- | --- | C3'endo | 0.012 |
| 1 | AA | U | 1049 | 8.5 | 88.1 | 10.5 | 55.3 | 350.8 | 34.5 | C3'endo | 0.213 |
| 1 | AA | C | 1054 | 20.3 | 107.5 | 356.7 | 120.4 | 32.9 | 139.9 | C3'endo | 0.0 |
| 1 | AA | U | 1065 | 293.7 | 64.8 | 246.9 | 74.4 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1125 | 322.8 | 134.8 | 3.4 | 72.5 | 18.9 | 352.9 | C3'endo | 0.01 |
| 1 | AA | U | 1136 | 76.6 | 349.8 | 89.1 | 334.9 | 102.4 | 347.1 | C3'endo | 0.0 |
| 1 | AA | U | 1212 | 299.4 | 63.2 | 272.5 | 65.8 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 1256 | 287.2 | 143.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1278 | 229.5 | 37.4 | 242.4 | 42.7 | --- | --- | C3'endo | 0.136 |
| 1 | AA | G | 1300 | 296.5 | 58.1 | 277.2 | 80.1 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1397 | 313.5 | 64.4 | 322.0 | 32.5 | 179.6 | 31.8 | C3'endo | 0.127 |
| 1 | AA | A | 1398 | 130.8 | 52.4 | 152.6 | 84.3 | --- | --- | C3'endo | 0.431 |
| 1 | AA | A | 1447 | 56.5 | 71.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 1491 | 202.3 | 287.0 | --- | --- | --- | --- | C3'endo | 0.601 |
| 1 | AW | U | 16 | 280.2 | 307.8 | 250.7 | 306.1 | --- | --- | C3'endo | 0.0 |
| 1 | AW | C | 17 | 321.6 | 48.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 34 | 88.4 | 269.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 74 | 273.8 | 45.8 | 236.2 | 32.9 | 187.3 | 41.0 | C3'endo | 0.0 |
| 1 | BA | G | 102 | 200.7 | 54.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 154A | 134.4 | 299.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 229 | 310.9 | 1.9 | 345.5 | 0.2 | 15.0 | 16.3 | C3'endo | 0.0 |
| 1 | BA | G | 248 | 119.5 | 313.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 272A | 39.0 | 324.0 | 48.4 | 306.8 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 277 | 324.4 | 49.0 | 350.2 | 66.2 | 359.9 | 64.9 | C3'endo | 0.521 |
| 1 | BA | G | 352 | 259.7 | 110.5 | 244.5 | 96.7 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 443 | 277.9 | 83.8 | 317.2 | 64.5 | 12.4 | 18.6 | C3'endo | 0.527 |
| 1 | BA | A | 480 | 111.0 | 301.4 | --- | --- | --- | --- | C3'endo | 0.01 |
| 1 | BA | U | 504 | 332.6 | 86.9 | 329.9 | 63.1 | 352.3 | 348.9 | C3'endo | 0.052 |
| 1 | BA | G | 508 | 306.6 | 81.3 | 285.4 | 71.6 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 645 | 74.1 | 327.6 | 67.5 | 305.6 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 654H | 148.6 | 309.4 | --- | --- | --- | --- | C3'endo | 0.437 |
| 1 | BA | C | 654M | 231.4 | 117.0 | 251.3 | 123.8 | --- | --- | C3'endo | 0.01 |
| 1 | BA | U | 747 | 324.9 | 31.3 | 4.4 | 15.1 | 132.6 | 9.0 | C3'endo | 0.238 |
| 1 | BA | A | 751 | 298.3 | 105.9 | 322.4 | 122.2 | 318.3 | 121.8 | C3'endo | 0.689 |
| 1 | BA | U | 958 | 306.0 | 92.6 | 350.8 | 80.5 | 29.5 | 331.9 | C3'endo | 0.0 |
| 1 | BA | A | 1045 | 247.1 | 103.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1046 | 349.5 | 11.5 | 327.8 | 317.7 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 1135 | 87.4 | 262.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 1136 | 12.5 | 160.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1273 | 332.3 | 144.4 | 33.7 | 111.7 | 65.9 | 80.3 | C3'endo | 0.0 |
| 1 | BA | U | 1420 | 58.2 | 263.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 1509 | 315.9 | 321.7 | 296.8 | 343.9 | 288.2 | 329.3 | C3'endo | 0.0 |
| 1 | BA | G | 1541 | 70.1 | 127.5 | 111.0 | 106.9 | 49.3 | 165.3 | C3'endo | 0.0 |
| 1 | BA | C | 1543 | 325.5 | 338.8 | 28.6 | 307.5 | --- | --- | C3'endo | 0.09 |
| 1 | BA | U | 1757 | 333.1 | 351.8 | 332.0 | 329.3 | 52.5 | 341.5 | C3'endo | 0.277 |
| 1 | BA | C | 1914 | 253.5 | 269.4 | 242.3 | 269.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 1965 | 264.5 | 342.9 | --- | --- | --- | --- | C3'endo | 0.032 |
| 1 | BA | A | 1971 | 9.2 | 342.1 | 1.7 | 334.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 2030 | 11.6 | 124.5 | 36.1 | 92.5 | 18.4 | 78.7 | C3'endo | 0.592 |
| 1 | BA | C | 2055 | 229.1 | 49.3 | 252.8 | 56.8 | 305.6 | 120.2 | C3'endo | 0.0 |
| 1 | BA | U | 2130 | 127.8 | 115.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 2132 | 324.4 | 352.2 | 353.7 | 327.9 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 2218 | 1.2 | 332.6 | 19.7 | 317.9 | --- | --- | C3'endo | 0.01 |
| 1 | BA | C | 2424 | 88.9 | 336.6 | 84.5 | 323.8 | --- | --- | C3'endo | 0.294 |
| 1 | BA | G | 2428 | 294.7 | 100.5 | 277.5 | 96.6 | --- | --- | C3'endo | 0.022 |
| 1 | BA | G | 2505 | 346.3 | 147.6 | 345.2 | 135.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 2573 | 255.0 | 65.7 | 251.8 | 76.3 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 2660 | 70.9 | 287.2 | 83.9 | 298.8 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 2689 | 102.4 | 51.5 | 118.8 | 58.7 | 182.6 | 79.5 | C3'endo | 0.0 |
| 1 | BA | A | 2712A | 91.6 | 334.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 2765 | 85.1 | 261.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 2779 | 216.6 | 73.9 | 249.1 | 40.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2893 | 211.0 | 28.4 | 231.5 | 42.2 | --- | --- | C3'endo | 0.0 |
| 1 | BB | U | 41 | 287.7 | 334.5 | 345.5 | 304.4 | --- | --- | C3'endo | 0.0 |
| 1 | BB | C | 109 | 211.0 | 43.2 | --- | --- | --- | --- | C3'endo | 0.187 |
| 1 | CA | U | 30 | 216.4 | 303.2 | --- | --- | --- | --- | C3'endo | 0.335 |
| 1 | CA | C | 89 | 121.0 | 353.7 | 147.8 | 349.5 | 180.4 | 4.0 | C3'endo | 0.0 |
| 1 | CA | A | 119 | 221.0 | 73.4 | 229.0 | 67.2 | --- | --- | C3'endo | 0.849 |
| 1 | CA | A | 243 | 224.6 | 116.7 | 230.0 | 79.6 | --- | --- | C3'endo | 0.818 |
| 1 | CA | G | 247 | 264.3 | 135.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 250 | 224.7 | 131.6 | --- | --- | --- | --- | C3'endo | 0.261 |
| 1 | CA | G | 266 | 331.0 | 123.1 | 345.4 | 86.4 | 313.9 | 53.4 | C3'endo | 0.0 |
| 1 | CA | C | 352 | 78.9 | 95.0 | 77.6 | 65.3 | 94.1 | 345.7 | C3'endo | 0.0 |
| 1 | CA | A | 353 | 10.2 | 115.8 | 5.1 | 119.3 | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 530 | 207.5 | 59.3 | --- | --- | --- | --- | C3'endo | 0.668 |
| 1 | CA | A | 563 | 108.5 | 103.9 | 103.7 | 81.4 | 107.9 | 28.5 | C3'endo | 0.315 |
| 1 | CA | U | 723 | 51.8 | 294.0 | 59.8 | 298.3 | --- | --- | C3'endo | 0.285 |
| 1 | CA | C | 754 | 115.6 | 312.8 | 103.7 | 316.7 | --- | --- | C3'endo | 0.647 |
| 1 | CA | A | 816 | 71.0 | 30.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 839 | 80.0 | 17.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 841 | 332.2 | 316.4 | 334.6 | 319.5 | 9.9 | 348.3 | C3'endo | 0.0 |
| 1 | CA | U | 992 | 320.2 | 96.0 | 292.2 | 80.6 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1004 | 210.7 | 127.1 | --- | --- | --- | --- | C3'endo | 0.053 |
| 1 | CA | A | 1005 | 261.3 | 281.2 | 248.7 | 287.5 | --- | --- | C3'endo | 0.012 |
| 1 | CA | C | 1030B | 303.9 | 280.9 | 332.5 | 283.3 | 318.5 | 302.8 | C3'endo | 0.124 |
| 1 | CA | U | 1049 | 8.1 | 88.0 | 10.5 | 55.0 | 349.2 | 34.7 | C3'endo | 0.22 |
| 1 | CA | C | 1054 | 20.2 | 107.7 | 356.7 | 120.5 | 32.9 | 141.0 | C3'endo | 0.0 |
| 1 | CA | U | 1065 | 293.9 | 64.7 | 247.0 | 74.3 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1125 | 323.2 | 134.8 | 3.3 | 72.7 | 18.9 | 353.0 | C3'endo | 0.01 |
| 1 | CA | U | 1136 | 76.0 | 350.3 | 88.9 | 335.2 | 102.4 | 347.2 | C3'endo | 0.0 |
| 1 | CA | U | 1212 | 299.2 | 63.3 | 272.4 | 65.8 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1256 | 287.8 | 142.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1278 | 229.7 | 37.3 | 242.6 | 42.7 | --- | --- | C3'endo | 0.144 |
| 1 | CA | G | 1300 | 296.5 | 57.8 | 277.3 | 80.1 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 1397 | 321.7 | 55.9 | 324.3 | 29.3 | 201.5 | 37.5 | C3'endo | 0.154 |
| 1 | CA | A | 1398 | 132.2 | 57.6 | 151.6 | 89.6 | --- | --- | C3'endo | 0.079 |
| 1 | CA | A | 1447 | 57.9 | 93.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CW | U | 16 | 289.2 | 301.9 | 264.2 | 296.6 | --- | --- | C3'endo | 0.0 |
| 1 | CW | C | 17 | 321.3 | 45.3 | 0.5 | 34.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 34 | 87.7 | 269.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 74 | 274.4 | 45.4 | 237.2 | 33.0 | 187.7 | 41.6 | C3'endo | 0.0 |
| 1 | DA | G | 102 | 201.0 | 53.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 154A | 134.4 | 299.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 229 | 311.0 | 1.7 | 345.4 | 359.9 | 15.0 | 16.1 | C3'endo | 0.0 |
| 1 | DA | G | 248 | 118.4 | 312.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 272A | 38.4 | 324.5 | 47.7 | 307.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 277 | 323.8 | 50.1 | 349.6 | 66.7 | 359.7 | 65.1 | C3'endo | 0.525 |
| 1 | DA | G | 352 | 259.6 | 110.0 | 244.4 | 96.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 443 | 277.1 | 84.2 | 317.3 | 64.7 | 12.8 | 18.9 | C3'endo | 0.537 |
| 1 | DA | A | 480 | 111.8 | 301.4 | --- | --- | --- | --- | C3'endo | 0.014 |
| 1 | DA | U | 504 | 332.9 | 86.6 | 330.0 | 63.2 | 352.3 | 349.1 | C3'endo | 0.089 |
| 1 | DA | G | 508 | 306.6 | 81.8 | 285.4 | 72.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 645 | 74.3 | 327.7 | 67.7 | 305.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 654H | 148.5 | 309.1 | --- | --- | --- | --- | C3'endo | 0.433 |
| 1 | DA | C | 654M | 231.4 | 116.8 | 251.2 | 123.7 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 747 | 324.4 | 31.8 | 2.9 | 15.4 | 132.0 | 9.2 | C3'endo | 0.201 |
| 1 | DA | A | 751 | 298.9 | 106.2 | 322.1 | 122.3 | 317.9 | 121.5 | C3'endo | 0.725 |
| 1 | DA | U | 958 | 304.9 | 93.0 | 350.4 | 80.8 | 29.6 | 333.5 | C3'endo | 0.0 |
| 1 | DA | A | 1045 | 247.0 | 103.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1046 | 350.0 | 11.6 | 328.0 | 317.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 1135 | 87.8 | 262.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 1136 | 12.0 | 159.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1255 | 262.9 | 11.2 | --- | --- | --- | --- | C3'endo | 0.54 |
| 1 | DA | U | 1273 | 331.9 | 145.1 | 33.7 | 112.2 | 65.9 | 80.2 | C3'endo | 0.0 |
| 1 | DA | U | 1420 | 58.5 | 264.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 1509 | 316.0 | 321.4 | 296.8 | 343.6 | 288.1 | 329.2 | C3'endo | 0.0 |
| 1 | DA | G | 1541 | 70.1 | 127.5 | 111.1 | 106.9 | 49.5 | 165.7 | C3'endo | 0.0 |
| 1 | DA | C | 1543 | 325.3 | 338.7 | 28.7 | 307.4 | --- | --- | C3'endo | 0.091 |
| 1 | DA | U | 1757 | 332.5 | 351.8 | 331.8 | 329.6 | 53.6 | 341.2 | C3'endo | 0.335 |
| 1 | DA | C | 1914 | 253.3 | 269.9 | 242.4 | 269.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 1965 | 264.6 | 342.8 | --- | --- | --- | --- | C3'endo | 0.016 |
| 1 | DA | A | 1969 | 210.6 | 80.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1971 | 8.4 | 342.6 | 0.8 | 334.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 2030 | 12.0 | 124.7 | 36.4 | 92.6 | 18.4 | 78.5 | C3'endo | 0.645 |
| 1 | DA | C | 2055 | 229.8 | 49.7 | 253.2 | 57.2 | 305.4 | 120.5 | C3'endo | 0.0 |
| 1 | DA | U | 2130 | 128.1 | 115.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2132 | 324.2 | 352.5 | 353.3 | 328.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2218 | 1.2 | 332.2 | 19.6 | 317.8 | --- | --- | C3'endo | 0.01 |
| 1 | DA | C | 2424 | 88.3 | 336.5 | 83.8 | 323.1 | --- | --- | C3'endo | 0.249 |
| 1 | DA | G | 2428 | 293.7 | 100.4 | 276.5 | 97.1 | --- | --- | C3'endo | 0.032 |
| 1 | DA | G | 2505 | 346.2 | 146.9 | 345.7 | 134.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 2573 | 255.1 | 66.0 | 252.0 | 77.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 2660 | 69.6 | 288.1 | 83.6 | 298.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2689 | 102.8 | 51.9 | 119.9 | 58.8 | 183.0 | 79.8 | C3'endo | 0.0 |
| 1 | DA | A | 2712A | 91.7 | 333.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 2765 | 85.9 | 260.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2779 | 217.2 | 73.3 | 249.4 | 39.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2893 | 211.0 | 28.4 | 231.5 | 42.2 | --- | --- | C3'endo | 0.0 |
| 1 | DB | U | 41 | 288.0 | 334.9 | 345.6 | 304.6 | --- | --- | C3'endo | 0.0 |
| 1 | DB | C | 109 | 211.1 | 43.8 | --- | --- | --- | --- | C3'endo | 0.176 |
| 1 | AA | C | 328 | --- | --- | 260.2 | 74.8 | 291.0 | 90.8 | C3'endo | 0.0 |
| 1 | AA | G | 484 | --- | --- | 114.9 | 131.4 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1029 | --- | --- | 230.5 | 144.8 | --- | --- | C3'endo | 0.347 |
| 1 | AA | C | 1030B | --- | --- | 332.2 | 283.4 | 318.4 | 302.9 | C3'endo | 0.119 |
| 1 | AA | C | 1363 | --- | --- | 125.2 | 351.6 | --- | --- | C3'endo | 0.0 |
| 1 | AW | A | 21 | --- | --- | 275.5 | 164.2 | --- | --- | C3'endo | 0.0 |
| 1 | AW | C | 49 | --- | --- | 281.5 | 278.5 | --- | --- | C3'endo | 0.076 |
| 1 | BA | U | 271L | --- | --- | 236.9 | 101.8 | --- | --- | C3'endo | 0.181 |
| 1 | BA | G | 275 | --- | --- | 66.5 | 151.9 | 49.5 | 124.6 | C3'endo | 0.0 |
| 1 | BA | A | 412 | --- | --- | 258.6 | 264.1 | --- | --- | C3'endo | 0.11 |
| 1 | BA | G | 614B | --- | --- | 292.8 | 158.7 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 763 | --- | --- | 130.9 | 142.6 | 105.2 | 115.8 | C3'endo | 0.655 |
| 1 | BA | A | 781 | --- | --- | 351.9 | 82.9 | 346.9 | 23.8 | C3'endo | 0.712 |
| 1 | BA | G | 1044 | --- | --- | 142.7 | 126.9 | --- | --- | C3'endo | 0.636 |
| 1 | BA | G | 1047 | --- | --- | 230.7 | 129.0 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 1173 | --- | --- | 292.1 | 281.9 | 337.8 | 316.3 | C3'endo | 0.0 |
| 1 | BA | A | 1174 | --- | --- | 224.0 | 35.3 | 289.8 | 4.9 | C3'endo | 0.0 |
| 1 | BA | A | 1177 | --- | --- | 239.3 | 66.3 | --- | --- | C3'endo | 0.186 |
| 1 | BA | A | 1494 | --- | --- | 152.0 | 121.4 | 150.9 | 70.0 | C3'endo | 0.0 |
| 1 | BA | U | 1540 | --- | --- | 225.4 | 287.9 | 305.9 | 182.0 | C3'endo | 0.274 |
| 1 | BA | U | 1779 | --- | --- | 155.3 | 26.1 | 131.7 | 39.2 | C3'endo | 0.271 |
| 1 | BA | A | 2031 | --- | --- | 119.5 | 14.6 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2133 | --- | --- | 231.9 | 126.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2207 | --- | --- | 332.2 | 131.9 | 14.0 | 41.1 | C3'endo | 0.0 |
| 1 | BA | A | 2208 | --- | --- | 91.3 | 123.9 | 103.1 | 25.6 | C3'endo | 0.0 |
| 1 | BA | A | 2267 | --- | --- | 144.3 | 33.0 | --- | --- | C3'endo | 0.351 |
| 1 | BA | A | 2577 | --- | --- | 281.0 | 355.4 | --- | --- | C3'endo | 0.446 |
| 1 | BA | C | 2755 | --- | --- | 353.7 | 150.8 | 353.2 | 105.0 | C3'endo | 0.215 |
| 1 | BA | G | 2777 | --- | --- | 322.5 | 66.2 | --- | --- | C3'endo | 0.505 |
| 1 | BA | A | 2883 | --- | --- | 157.5 | 341.9 | 152.5 | 352.7 | C3'endo | 0.551 |
| 1 | BB | A | 13 | --- | --- | 237.8 | 147.7 | --- | --- | C3'endo | 0.396 |
| 1 | BB | A | 66 | --- | --- | 231.0 | 119.2 | --- | --- | C3'endo | 0.715 |
| 1 | CA | C | 328 | --- | --- | 260.4 | 74.9 | 291.4 | 91.0 | C3'endo | 0.0 |
| 1 | CA | G | 484 | --- | --- | 114.6 | 131.5 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 1029 | --- | --- | 230.6 | 144.8 | --- | --- | C3'endo | 0.344 |
| 1 | CA | C | 1363 | --- | --- | 125.4 | 351.6 | --- | --- | C3'endo | 0.0 |
| 1 | CW | A | 21 | --- | --- | 261.6 | 157.4 | --- | --- | C3'endo | 0.0 |
| 1 | CW | C | 49 | --- | --- | 318.9 | 281.4 | --- | --- | C3'endo | 0.526 |
| 1 | DA | U | 271L | --- | --- | 237.1 | 101.9 | --- | --- | C3'endo | 0.19 |
| 1 | DA | G | 275 | --- | --- | 66.5 | 152.0 | 49.5 | 124.6 | C3'endo | 0.0 |
| 1 | DA | A | 412 | --- | --- | 259.0 | 264.1 | --- | --- | C3'endo | 0.1 |
| 1 | DA | G | 614B | --- | --- | 292.7 | 158.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 763 | --- | --- | 131.0 | 142.6 | 105.3 | 115.8 | C3'endo | 0.68 |
| 1 | DA | A | 781 | --- | --- | 352.1 | 82.9 | 346.7 | 24.0 | C3'endo | 0.734 |
| 1 | DA | G | 1044 | --- | --- | 142.5 | 126.7 | --- | --- | C3'endo | 0.642 |
| 1 | DA | G | 1047 | --- | --- | 230.3 | 128.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 1173 | --- | --- | 292.0 | 281.9 | 337.7 | 316.2 | C3'endo | 0.0 |
| 1 | DA | A | 1174 | --- | --- | 223.9 | 35.5 | 289.7 | 4.7 | C3'endo | 0.0 |
| 1 | DA | A | 1177 | --- | --- | 239.2 | 66.5 | --- | --- | C3'endo | 0.19 |
| 1 | DA | A | 1494 | --- | --- | 152.3 | 121.1 | 151.1 | 69.9 | C3'endo | 0.0 |
| 1 | DA | U | 1540 | --- | --- | 225.5 | 288.1 | 306.0 | 182.1 | C3'endo | 0.283 |
| 1 | DA | U | 1779 | --- | --- | 155.3 | 27.3 | 133.1 | 40.5 | C3'endo | 0.259 |
| 1 | DA | A | 2031 | --- | --- | 119.5 | 15.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2133 | --- | --- | 231.6 | 126.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2207 | --- | --- | 332.2 | 131.9 | 14.0 | 41.0 | C3'endo | 0.0 |
| 1 | DA | A | 2208 | --- | --- | 91.4 | 124.0 | 103.0 | 25.6 | C3'endo | 0.0 |
| 1 | DA | A | 2267 | --- | --- | 144.6 | 32.9 | --- | --- | C3'endo | 0.366 |
| 1 | DA | A | 2577 | --- | --- | 280.6 | 355.8 | --- | --- | C3'endo | 0.433 |
| 1 | DA | C | 2755 | --- | --- | 353.0 | 151.2 | 353.2 | 105.3 | C3'endo | 0.201 |
| 1 | DA | G | 2777 | --- | --- | 323.2 | 66.1 | --- | --- | C3'endo | 0.516 |
| 1 | DA | A | 2883 | --- | --- | 157.0 | 341.6 | 152.5 | 352.1 | C3'endo | 0.506 |
| 1 | DB | A | 13 | --- | --- | 237.4 | 147.3 | --- | --- | C3'endo | 0.411 |
| 1 | DB | A | 66 | --- | --- | 231.4 | 119.0 | --- | --- | C3'endo | 0.717 |
| 1 | AA | G | 6 | --- | --- | --- | --- | 131.0 | 105.1 | C3'endo | 0.069 |
| 1 | AA | A | 397 | --- | --- | --- | --- | 335.9 | 68.9 | C3'endo | 0.0 |
| 1 | AA | U | 560 | 3.8 | 87.7 | --- | --- | 55.8 | 346.8 | C3'endo | 0.25 |
| 1 | AA | A | 665 | --- | --- | --- | --- | 16.2 | 157.2 | C3'endo | 0.016 |
| 1 | AA | A | 722 | --- | --- | --- | --- | 153.0 | 64.6 | C3'endo | 0.789 |
| 1 | AA | C | 1027 | --- | --- | --- | --- | 306.6 | 171.5 | C3'endo | 0.0 |
| 1 | AA | A | 1183 | 355.2 | 290.5 | --- | --- | 26.7 | 186.9 | C3'endo | 0.524 |
| 1 | AA | G | 1202 | --- | --- | --- | --- | 320.1 | 293.5 | C3'endo | 0.0 |
| 1 | AA | A | 1377 | --- | --- | --- | --- | 181.4 | 66.6 | C3'endo | 0.623 |
| 1 | AA | G | 1505 | --- | --- | --- | --- | 179.6 | 5.5 | C3'endo | 0.0 |
| 1 | AW | U | 50 | --- | --- | --- | --- | 289.9 | 108.6 | C3'endo | 0.17 |
| 1 | AW | C | 56 | --- | --- | --- | --- | 34.0 | 194.4 | C3'endo | 0.595 |
| 1 | AW | A | 64 | --- | --- | --- | --- | 298.2 | 157.3 | C3'endo | 0.089 |
| 1 | BA | A | 221 | 210.7 | 47.0 | --- | --- | 159.3 | 83.2 | C3'endo | 0.0 |
| 1 | BA | G | 388 | --- | --- | --- | --- | 76.3 | 145.0 | C3'endo | 0.0 |
| 1 | BA | C | 654I | --- | --- | --- | --- | 329.4 | 24.2 | C3'endo | 0.0 |
| 1 | BA | A | 887 | 240.7 | 115.9 | --- | --- | 197.2 | 57.2 | C3'endo | 0.185 |
| 1 | BA | U | 1033 | --- | --- | --- | --- | 6.1 | 152.5 | C3'endo | 0.0 |
| 1 | BA | C | 1043 | --- | --- | --- | --- | 295.7 | 146.3 | C3'endo | 0.488 |
| 1 | BA | G | 1056 | --- | --- | --- | --- | 298.9 | 80.0 | C3'endo | 0.181 |
| 1 | BA | G | 1107 | --- | --- | --- | --- | 298.1 | 169.6 | C3'endo | 0.551 |
| 1 | BA | A | 1274 | --- | --- | --- | --- | 359.8 | 135.7 | C3'endo | 0.168 |
| 1 | BA | A | 1301 | --- | --- | --- | --- | 138.4 | 108.4 | C3'endo | 0.0 |
| 1 | BA | U | 1534 | --- | --- | --- | --- | 350.1 | 310.1 | C3'endo | 0.0 |
| 1 | BA | A | 1700 | --- | --- | --- | --- | 344.7 | 299.8 | C3'endo | 0.1 |
| 1 | BA | A | 1785 | --- | --- | --- | --- | 124.3 | 89.9 | C3'endo | 0.619 |
| 1 | BA | G | 1816 | 310.9 | 17.1 | --- | --- | 291.2 | 80.7 | C3'endo | 0.0 |
| 1 | BA | G | 2131 | 220.2 | 91.2 | --- | --- | 131.0 | 344.1 | C3'endo | 0.0 |
| 1 | BA | G | 2282 | 200.5 | 38.2 | --- | --- | 189.8 | 36.0 | C3'endo | 0.876 |
| 1 | BA | G | 2307 | --- | --- | --- | --- | 309.7 | 186.5 | C3'endo | 0.0 |
| 1 | BA | G | 2308 | --- | --- | --- | --- | 26.7 | 130.8 | C3'endo | 0.0 |
| 1 | BA | A | 2309 | --- | --- | --- | --- | 49.7 | 158.9 | C3'endo | 0.183 |
| 1 | BA | G | 2405 | --- | --- | --- | --- | 275.1 | 67.4 | C3'endo | 0.672 |
| 1 | BA | A | 2476 | --- | --- | --- | --- | 355.4 | 136.4 | C3'endo | 0.0 |
| 1 | BA | C | 2477 | --- | --- | --- | --- | 102.6 | 74.3 | C3'endo | 0.0 |
| 1 | BA | G | 2502 | 334.0 | 45.2 | --- | --- | 140.9 | 63.2 | C3'endo | 0.0 |
| 1 | BA | G | 2529 | --- | --- | --- | --- | 36.1 | 341.6 | C3'endo | 0.0 |
| 1 | BA | A | 2530 | --- | --- | --- | --- | 113.8 | 142.3 | C3'endo | 0.652 |
| 1 | BA | U | 2688 | --- | --- | --- | --- | 278.2 | 338.4 | C3'endo | 0.56 |
| 1 | BA | G | 2872 | --- | --- | --- | --- | 79.0 | 125.3 | C3'endo | 0.0 |
| 1 | CA | G | 6 | --- | --- | --- | --- | 130.6 | 105.0 | C3'endo | 0.075 |
| 1 | CA | A | 397 | --- | --- | --- | --- | 336.0 | 68.8 | C3'endo | 0.0 |
| 1 | CA | U | 560 | 3.9 | 87.2 | --- | --- | 55.7 | 347.1 | C3'endo | 0.27 |
| 1 | CA | A | 665 | --- | --- | --- | --- | 16.4 | 157.7 | C3'endo | 0.02 |
| 1 | CA | A | 722 | --- | --- | --- | --- | 152.9 | 64.7 | C3'endo | 0.766 |
| 1 | CA | C | 1027 | --- | --- | --- | --- | 306.6 | 171.4 | C3'endo | 0.0 |
| 1 | CA | A | 1183 | 355.2 | 291.2 | --- | --- | 26.7 | 187.0 | C3'endo | 0.493 |
| 1 | CA | G | 1202 | --- | --- | --- | --- | 319.9 | 293.6 | C3'endo | 0.0 |
| 1 | CA | A | 1377 | --- | --- | --- | --- | 181.8 | 66.6 | C3'endo | 0.597 |
| 1 | CA | G | 1505 | --- | --- | --- | --- | 179.2 | 358.5 | C3'endo | 0.0 |
| 1 | DA | A | 221 | 210.0 | 47.8 | --- | --- | 159.4 | 83.2 | C3'endo | 0.0 |
| 1 | DA | G | 388 | --- | --- | --- | --- | 76.0 | 144.9 | C3'endo | 0.0 |
| 1 | DA | C | 654I | --- | --- | --- | --- | 329.4 | 23.9 | C3'endo | 0.0 |
| 1 | DA | A | 887 | 240.6 | 115.6 | --- | --- | 197.0 | 57.1 | C3'endo | 0.186 |
| 1 | DA | U | 1033 | --- | --- | --- | --- | 6.3 | 152.0 | C3'endo | 0.0 |
| 1 | DA | C | 1043 | --- | --- | --- | --- | 295.7 | 146.3 | C3'endo | 0.496 |
| 1 | DA | G | 1056 | --- | --- | --- | --- | 298.8 | 79.8 | C3'endo | 0.176 |
| 1 | DA | G | 1107 | --- | --- | --- | --- | 298.0 | 169.5 | C3'endo | 0.55 |
| 1 | DA | A | 1274 | --- | --- | --- | --- | 0.1 | 135.9 | C3'endo | 0.167 |
| 1 | DA | A | 1301 | --- | --- | --- | --- | 139.1 | 109.1 | C3'endo | 0.0 |
| 1 | DA | U | 1534 | --- | --- | --- | --- | 350.0 | 310.0 | C3'endo | 0.0 |
| 1 | DA | A | 1700 | --- | --- | --- | --- | 344.4 | 299.0 | C3'endo | 0.105 |
| 1 | DA | A | 1785 | --- | --- | --- | --- | 124.3 | 89.4 | C3'endo | 0.534 |
| 1 | DA | G | 1816 | 311.2 | 16.6 | --- | --- | 291.1 | 80.5 | C3'endo | 0.0 |
| 1 | DA | G | 2131 | 220.6 | 91.3 | --- | --- | 130.6 | 343.8 | C3'endo | 0.0 |
| 1 | DA | G | 2282 | 200.8 | 38.7 | --- | --- | 190.1 | 36.0 | C3'endo | 0.848 |
| 1 | DA | G | 2307 | --- | --- | --- | --- | 309.4 | 186.1 | C3'endo | 0.0 |
| 1 | DA | G | 2308 | --- | --- | --- | --- | 26.9 | 131.1 | C3'endo | 0.0 |
| 1 | DA | A | 2309 | --- | --- | --- | --- | 49.7 | 158.8 | C3'endo | 0.173 |
| 1 | DA | G | 2405 | --- | --- | --- | --- | 275.3 | 67.4 | C3'endo | 0.66 |
| 1 | DA | A | 2476 | --- | --- | --- | --- | 355.5 | 136.2 | C3'endo | 0.0 |
| 1 | DA | C | 2477 | --- | --- | --- | --- | 102.9 | 74.6 | C3'endo | 0.0 |
| 1 | DA | G | 2502 | 333.6 | 45.0 | --- | --- | 141.5 | 63.3 | C3'endo | 0.0 |
| 1 | DA | G | 2529 | --- | --- | --- | --- | 36.1 | 342.1 | C3'endo | 0.0 |
| 1 | DA | A | 2530 | --- | --- | --- | --- | 113.4 | 142.3 | C3'endo | 0.626 |
| 1 | DA | U | 2688 | --- | --- | --- | --- | 279.1 | 338.3 | C3'endo | 0.546 |
| 1 | DA | G | 2872 | --- | --- | --- | --- | 79.4 | 125.4 | C3'endo | 0.0 |
| 1 | AA | A | 51 | 19.0 | 58.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 79 | 258.0 | 177.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 130 | 341.1 | 252.5 | --- | --- | --- | --- | C2'endo | 0.798 |
| 1 | AA | G | 189G | 10.7 | 25.2 | 108.5 | 345.0 | --- | --- | C2'endo | 0.07 |
| 1 | AA | A | 344 | 75.8 | 3.4 | --- | --- | --- | --- | C2'endo | 0.451 |
| 1 | AA | A | 533 | 223.2 | 349.3 | 334.2 | 243.5 | 313.5 | 198.5 | C2'endo | 0.0 |
| 1 | AA | A | 815 | 74.2 | 21.8 | 59.8 | 359.0 | --- | --- | C2'endo | 0.044 |
| 1 | AA | C | 817 | 89.9 | 146.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 974 | 88.9 | 59.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 975 | 31.0 | 71.5 | 36.8 | 66.5 | 64.8 | 71.1 | C2'endo | 0.0 |
| 1 | AA | G | 1094 | 26.5 | 51.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 1285 | 337.2 | 191.5 | --- | --- | --- | --- | C2'endo | 0.257 |
| 1 | AA | C | 1452 | 112.6 | 73.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AV | G | 18 | 321.0 | 234.6 | 39.1 | 214.0 | --- | --- | C2'endo | 0.0 |
| 1 | AV | G | 19 | 221.3 | 356.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AW | A | 9 | 253.7 | 285.7 | --- | --- | --- | --- | C2'endo | 0.024 |
| 1 | BA | U | 9 | 150.7 | 257.3 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | A | 196 | 305.4 | 229.3 | 327.4 | 240.4 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 330 | 95.1 | 235.9 | 144.6 | 202.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 386 | 105.7 | 331.6 | 116.2 | 313.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 457 | 344.5 | 185.4 | 3.9 | 154.1 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 529 | 120.4 | 94.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 532 | 147.8 | 26.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 573 | 249.9 | 197.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 574 | 30.6 | 82.3 | 69.4 | 53.9 | --- | --- | C2'endo | 0.272 |
| 1 | BA | A | 614C | 332.6 | 239.1 | --- | --- | --- | --- | C2'endo | 0.197 |
| 1 | BA | A | 627 | 310.3 | 183.0 | 40.0 | 154.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 654K | 235.9 | 28.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 945 | 92.5 | 224.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 974 | 76.7 | 14.9 | 116.0 | 355.0 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 975 | 68.1 | 18.3 | 63.9 | 17.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1025 | 47.0 | 36.3 | 106.4 | 27.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1048 | 326.1 | 165.7 | --- | --- | --- | --- | C2'endo | 0.382 |
| 1 | BA | A | 1070 | 131.9 | 3.5 | 122.5 | 329.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1175 | 154.2 | 68.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1252 | 353.8 | 237.9 | --- | --- | --- | --- | C2'endo | 0.42 |
| 1 | BA | G | 1416 | 318.7 | 119.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1453 | 55.8 | 206.1 | --- | --- | --- | --- | C2'endo | 0.703 |
| 1 | BA | A | 1722 | 17.0 | 251.8 | 72.0 | 197.1 | 28.0 | 106.5 | C2'endo | 0.0 |
| 1 | BA | G | 1758 | 245.3 | 279.9 | --- | --- | --- | --- | C2'endo | 0.387 |
| 1 | BA | A | 1913 | 94.3 | 75.3 | 88.6 | 99.1 | --- | --- | C2'endo | 0.03 |
| 1 | BA | G | 1930 | 152.9 | 70.4 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | U | 1963 | 36.8 | 224.0 | 44.5 | 190.7 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1992 | 279.3 | 155.8 | --- | --- | --- | --- | C2'endo | 0.264 |
| 1 | BA | G | 2032 | 325.4 | 243.2 | --- | --- | --- | --- | C2'endo | 0.11 |
| 1 | BA | A | 2225 | 281.3 | 5.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2266 | 62.4 | 75.0 | --- | --- | --- | --- | C2'endo | 0.654 |
| 1 | BA | A | 2311 | 255.0 | 272.8 | 289.1 | 264.0 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 2319 | 132.5 | 79.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2346 | 342.6 | 36.5 | 351.2 | 347.9 | --- | --- | C2'endo | 0.367 |
| 1 | BA | A | 2425 | 104.8 | 67.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2602 | 72.2 | 35.4 | 36.9 | 36.5 | 4.6 | 17.4 | C2'endo | 0.0 |
| 1 | BA | A | 2662 | 153.2 | 40.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2713 | 56.3 | 235.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 2791 | 129.5 | 69.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 51 | 19.4 | 57.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | G | 79 | 258.0 | 177.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 130 | 341.1 | 252.5 | --- | --- | --- | --- | C2'endo | 0.794 |
| 1 | CA | G | 189G | 11.1 | 24.6 | 108.7 | 345.0 | --- | --- | C2'endo | 0.065 |
| 1 | CA | A | 344 | 72.5 | 6.6 | --- | --- | --- | --- | C2'endo | 0.445 |
| 1 | CA | A | 533 | 223.5 | 348.4 | 334.4 | 242.9 | 313.1 | 198.6 | C2'endo | 0.0 |
| 1 | CA | A | 815 | 74.0 | 21.9 | 59.5 | 359.0 | --- | --- | C2'endo | 0.046 |
| 1 | CA | U | 820 | 166.1 | 0.4 | --- | --- | --- | --- | C2'endo | 0.227 |
| 1 | CA | A | 974 | 89.3 | 59.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 975 | 31.2 | 71.2 | 37.2 | 66.3 | 64.8 | 71.1 | C2'endo | 0.0 |
| 1 | CA | G | 1094 | 26.4 | 51.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1285 | 336.4 | 192.1 | --- | --- | --- | --- | C2'endo | 0.263 |
| 1 | CA | A | 1442B | 119.8 | 148.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 9 | 150.7 | 256.9 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DA | A | 196 | 303.9 | 229.0 | 326.1 | 239.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 330 | 95.5 | 236.1 | 144.4 | 203.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 386 | 106.0 | 333.4 | 117.1 | 315.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 457 | 343.4 | 186.2 | 3.7 | 154.3 | 319.6 | 158.3 | C2'endo | 0.0 |
| 1 | DA | A | 529 | 119.7 | 94.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 532 | 148.3 | 25.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 573 | 249.6 | 197.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 574 | 31.0 | 82.7 | 70.0 | 54.1 | --- | --- | C2'endo | 0.288 |
| 1 | DA | A | 614C | 334.0 | 238.3 | --- | --- | --- | --- | C2'endo | 0.166 |
| 1 | DA | A | 627 | 307.1 | 185.1 | 39.7 | 154.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 654K | 235.8 | 27.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 945 | 92.3 | 224.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 974 | 76.8 | 14.5 | 115.6 | 355.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 975 | 68.4 | 18.5 | 63.5 | 17.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1025 | 47.9 | 34.6 | 106.7 | 25.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1048 | 326.4 | 165.5 | --- | --- | --- | --- | C2'endo | 0.376 |
| 1 | DA | A | 1070 | 131.8 | 3.1 | 122.5 | 329.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1112 | 282.9 | 158.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1175 | 154.1 | 68.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1252 | 353.0 | 238.1 | 36.0 | 207.4 | --- | --- | C2'endo | 0.415 |
| 1 | DA | G | 1416 | 318.5 | 118.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1453 | 55.7 | 205.5 | --- | --- | --- | --- | C2'endo | 0.668 |
| 1 | DA | A | 1722 | 17.9 | 251.4 | 72.4 | 197.0 | 28.2 | 106.6 | C2'endo | 0.0 |
| 1 | DA | G | 1758 | 245.2 | 279.9 | --- | --- | --- | --- | C2'endo | 0.404 |
| 1 | DA | A | 1913 | 92.8 | 75.6 | 88.1 | 99.0 | --- | --- | C2'endo | 0.048 |
| 1 | DA | G | 1930 | 152.4 | 70.1 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DA | U | 1963 | 37.6 | 223.9 | 44.8 | 190.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 2032 | 324.6 | 243.7 | --- | --- | --- | --- | C2'endo | 0.104 |
| 1 | DA | A | 2225 | 280.7 | 5.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2266 | 61.3 | 75.7 | --- | --- | --- | --- | C2'endo | 0.622 |
| 1 | DA | A | 2311 | 254.3 | 272.5 | 288.5 | 264.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 2319 | 129.0 | 79.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2346 | 342.5 | 35.9 | 351.2 | 348.1 | --- | --- | C2'endo | 0.366 |
| 1 | DA | A | 2425 | 104.7 | 67.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2602 | 72.9 | 34.8 | 37.6 | 36.1 | 7.5 | 17.1 | C2'endo | 0.0 |
| 1 | DA | A | 2662 | 153.8 | 39.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2712 | 335.3 | 204.2 | 32.8 | 158.5 | 99.9 | 105.6 | C2'endo | 0.0 |
| 1 | DA | A | 2713 | 57.1 | 235.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 2791 | 128.8 | 69.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 8 | --- | --- | 279.3 | 239.7 | 297.4 | 260.6 | C2'endo | 0.45 |
| 1 | AA | A | 50 | --- | --- | 75.7 | 87.3 | 84.1 | 98.6 | C2'endo | 0.01 |
| 1 | AA | A | 60 | --- | --- | 26.5 | 133.6 | --- | --- | C2'endo | 0.186 |
| 1 | AA | U | 189F | --- | --- | 322.1 | 245.1 | 316.1 | 214.7 | C2'endo | 0.048 |
| 1 | AA | A | 451 | --- | --- | 87.3 | 111.0 | --- | --- | C2'endo | 0.299 |
| 1 | AA | A | 461 | --- | --- | 57.1 | 196.4 | 33.1 | 143.9 | C2'endo | 0.0 |
| 1 | AA | A | 496 | --- | --- | 152.7 | 205.4 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 1196 | --- | --- | 307.2 | 19.4 | 330.4 | 122.4 | C2'endo | 0.0 |
| 1 | AA | A | 1201 | --- | --- | 34.1 | 85.1 | 87.9 | 95.2 | C2'endo | 0.01 |
| 1 | AA | G | 1293 | --- | --- | 172.2 | 207.0 | --- | --- | C2'endo | 0.352 |
| 1 | AA | A | 1363A | --- | --- | 84.2 | 59.0 | --- | --- | C2'endo | 0.073 |
| 1 | AA | A | 1442B | --- | --- | 173.0 | 193.7 | --- | --- | C2'endo | 0.0 |
| 1 | AV | U | 47 | --- | --- | 321.4 | 324.8 | --- | --- | C2'endo | 0.0 |
| 1 | AV | C | 48 | --- | --- | 307.6 | 21.2 | --- | --- | C2'endo | 0.0 |
| 1 | AW | A | 7 | --- | --- | 195.2 | 324.6 | --- | --- | C2'endo | 0.083 |
| 1 | BA | U | 156 | --- | --- | 160.5 | 58.7 | --- | --- | C2'endo | 0.191 |
| 1 | BA | A | 265 | --- | --- | 80.0 | 155.1 | --- | --- | C2'endo | 0.311 |
| 1 | BA | G | 530 | --- | --- | 158.1 | 191.6 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 562 | --- | --- | 307.4 | 133.4 | --- | --- | C2'endo | 0.336 |
| 1 | BA | A | 654J | --- | --- | 138.5 | 314.5 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1325 | --- | --- | 340.4 | 248.2 | --- | --- | C2'endo | 0.123 |
| 1 | BA | G | 2661 | --- | --- | 283.2 | 266.6 | 341.3 | 300.3 | C2'endo | 0.0 |
| 1 | BA | C | 2799 | --- | --- | 320.8 | 185.3 | 336.5 | 235.2 | C2'endo | 0.0 |
| 1 | CA | A | 8 | --- | --- | 279.5 | 240.0 | 297.7 | 260.8 | C2'endo | 0.46 |
| 1 | CA | A | 50 | --- | --- | 75.5 | 87.1 | 84.1 | 98.7 | C2'endo | 0.01 |
| 1 | CA | A | 60 | --- | --- | 26.1 | 133.8 | --- | --- | C2'endo | 0.208 |
| 1 | CA | U | 189F | --- | --- | 321.7 | 245.0 | 316.0 | 214.8 | C2'endo | 0.048 |
| 1 | CA | A | 461 | --- | --- | 56.9 | 196.4 | 33.0 | 143.7 | C2'endo | 0.0 |
| 1 | CA | A | 496 | --- | --- | 152.9 | 205.5 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1196 | --- | --- | 307.1 | 19.6 | 330.0 | 121.7 | C2'endo | 0.0 |
| 1 | CA | A | 1201 | --- | --- | 34.3 | 85.4 | 87.7 | 95.3 | C2'endo | 0.01 |
| 1 | CA | G | 1293 | --- | --- | 172.2 | 207.0 | --- | --- | C2'endo | 0.361 |
| 1 | CA | A | 1363A | --- | --- | 84.6 | 58.7 | --- | --- | C2'endo | 0.076 |
| 1 | CA | C | 1452 | --- | --- | 148.2 | 52.1 | --- | --- | C2'endo | 0.0 |
| 1 | CV | G | 18 | --- | --- | 40.4 | 209.1 | --- | --- | C2'endo | 0.0 |
| 1 | CW | A | 7 | --- | --- | 194.1 | 338.8 | --- | --- | C2'endo | 0.093 |
| 1 | CW | C | 48 | --- | --- | 30.4 | 41.7 | --- | --- | C2'endo | 0.053 |
| 1 | DA | U | 156 | --- | --- | 160.2 | 58.4 | --- | --- | C2'endo | 0.19 |
| 1 | DA | A | 265 | --- | --- | 79.9 | 155.2 | --- | --- | C2'endo | 0.263 |
| 1 | DA | G | 530 | --- | --- | 157.9 | 192.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 562 | --- | --- | 307.7 | 134.6 | --- | --- | C2'endo | 0.29 |
| 1 | DA | A | 654J | --- | --- | 138.4 | 314.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1325 | --- | --- | 340.7 | 248.4 | --- | --- | C2'endo | 0.146 |
| 1 | DA | G | 2661 | --- | --- | 283.4 | 266.7 | 341.3 | 300.4 | C2'endo | 0.0 |
| 1 | DA | C | 2799 | --- | --- | 320.9 | 185.3 | 336.6 | 235.2 | C2'endo | 0.0 |
| 1 | AA | U | 65 | --- | --- | --- | --- | 0.1 | 28.3 | C2'endo | 0.653 |
| 1 | AA | G | 129A | --- | --- | --- | --- | 319.9 | 25.4 | C2'endo | 0.114 |
| 1 | AA | U | 561 | --- | --- | --- | --- | 60.3 | 123.9 | C2'endo | 0.0 |
| 1 | AA | A | 1157 | --- | --- | --- | --- | 66.2 | 84.5 | C2'endo | 0.449 |
| 1 | AW | U | 47 | --- | --- | --- | --- | 10.4 | 213.6 | C2'endo | 0.0 |
| 1 | BA | G | 321 | --- | --- | --- | --- | 337.1 | 298.1 | C2'endo | 0.624 |
| 1 | BA | G | 323 | 96.6 | 48.0 | --- | --- | 159.9 | 26.5 | C2'endo | 0.414 |
| 1 | BA | C | 456 | --- | --- | --- | --- | 48.3 | 155.1 | C2'endo | 0.0 |
| 1 | BA | U | 1060 | --- | --- | --- | --- | 74.9 | 75.1 | C2'endo | 0.521 |
| 1 | BA | U | 1061 | --- | --- | --- | --- | 38.5 | 198.2 | C2'endo | 0.156 |
| 1 | BA | U | 1205 | --- | --- | --- | --- | 0.5 | 15.3 | C2'endo | 0.0 |
| 1 | BA | C | 1428 | --- | --- | --- | --- | 147.3 | 282.9 | C2'endo | 0.0 |
| 1 | BA | G | 1674 | --- | --- | --- | --- | 332.5 | 92.3 | C2'endo | 0.0 |
| 1 | BA | A | 1698 | --- | --- | --- | --- | 86.9 | 84.0 | C2'endo | 0.902 |
| 1 | BA | U | 1739 | --- | --- | --- | --- | 50.9 | 199.8 | C2'endo | 0.0 |
| 1 | BA | G | 1740 | --- | --- | --- | --- | 148.7 | 275.0 | C2'endo | 0.0 |
| 1 | BA | A | 1900 | --- | --- | --- | --- | 297.1 | 19.5 | C2'endo | 0.0 |
| 1 | BA | U | 2092 | --- | --- | --- | --- | 82.9 | 117.8 | C2'endo | 0.54 |
| 1 | BA | U | 2118 | --- | --- | --- | --- | 17.6 | 210.0 | C2'endo | 0.0 |
| 1 | BA | A | 2119 | 303.1 | 288.1 | --- | --- | 356.5 | 191.4 | C2'endo | 0.143 |
| 1 | BA | U | 2249 | --- | --- | --- | --- | 300.8 | 265.7 | C2'endo | 0.683 |
| 1 | BA | G | 2345 | --- | --- | --- | --- | 27.0 | 78.7 | C2'endo | 0.036 |
| 1 | BA | A | 2360 | --- | --- | --- | --- | 266.3 | 271.3 | C2'endo | 0.0 |
| 1 | BA | G | 2384 | --- | --- | --- | --- | 262.5 | 257.9 | C2'endo | 0.88 |
| 1 | BA | A | 2572 | --- | --- | --- | --- | 52.8 | 148.0 | C2'endo | 0.133 |
| 1 | BA | U | 2702 | --- | --- | --- | --- | 50.5 | 139.8 | C2'endo | 0.046 |
| 1 | BA | U | 2712 | 334.8 | 204.3 | --- | --- | 100.1 | 106.1 | C2'endo | 0.0 |
| 1 | BA | U | 2866 | --- | --- | --- | --- | 76.6 | 164.1 | C2'endo | 0.637 |
| 1 | CA | U | 65 | --- | --- | --- | --- | 359.7 | 32.2 | C2'endo | 0.642 |
| 1 | CA | G | 129A | --- | --- | --- | --- | 322.1 | 25.2 | C2'endo | 0.117 |
| 1 | CA | U | 561 | --- | --- | --- | --- | 60.0 | 123.6 | C2'endo | 0.0 |
| 1 | CA | A | 1157 | --- | --- | --- | --- | 66.4 | 84.7 | C2'endo | 0.456 |
| 1 | CV | G | 19 | 228.0 | 352.5 | --- | --- | 251.0 | 15.4 | C2'endo | 0.0 |
| 1 | CV | U | 47 | 290.2 | 300.9 | --- | --- | 340.8 | 224.0 | C2'endo | 0.0 |
| 1 | DA | G | 321 | --- | --- | --- | --- | 337.2 | 297.1 | C2'endo | 0.609 |
| 1 | DA | G | 323 | 97.2 | 47.0 | --- | --- | 160.5 | 26.6 | C2'endo | 0.387 |
| 1 | DA | C | 456 | --- | --- | --- | --- | 48.3 | 153.1 | C2'endo | 0.0 |
| 1 | DA | U | 1060 | --- | --- | --- | --- | 74.8 | 75.1 | C2'endo | 0.527 |
| 1 | DA | U | 1061 | --- | --- | --- | --- | 38.5 | 198.2 | C2'endo | 0.156 |
| 1 | DA | U | 1205 | --- | --- | --- | --- | 1.6 | 14.9 | C2'endo | 0.0 |
| 1 | DA | C | 1428 | --- | --- | --- | --- | 147.3 | 282.4 | C2'endo | 0.0 |
| 1 | DA | G | 1674 | --- | --- | --- | --- | 332.2 | 92.6 | C2'endo | 0.0 |
| 1 | DA | A | 1698 | --- | --- | --- | --- | 86.7 | 84.4 | C2'endo | 0.926 |
| 1 | DA | U | 1739 | --- | --- | --- | --- | 50.8 | 199.6 | C2'endo | 0.0 |
| 1 | DA | G | 1740 | --- | --- | --- | --- | 148.7 | 275.1 | C2'endo | 0.0 |
| 1 | DA | A | 1900 | --- | --- | --- | --- | 297.3 | 19.2 | C2'endo | 0.0 |
| 1 | DA | U | 2092 | --- | --- | --- | --- | 84.5 | 119.3 | C2'endo | 0.591 |
| 1 | DA | U | 2118 | --- | --- | --- | --- | 17.5 | 209.8 | C2'endo | 0.0 |
| 1 | DA | A | 2119 | 302.7 | 288.5 | --- | --- | 356.7 | 191.3 | C2'endo | 0.142 |
| 1 | DA | U | 2249 | --- | --- | --- | --- | 300.7 | 265.1 | C2'endo | 0.691 |
| 1 | DA | G | 2345 | --- | --- | --- | --- | 27.1 | 77.3 | C2'endo | 0.048 |
| 1 | DA | A | 2360 | --- | --- | --- | --- | 266.0 | 270.4 | C2'endo | 0.0 |
| 1 | DA | G | 2384 | --- | --- | --- | --- | 262.6 | 257.9 | C2'endo | 0.845 |
| 1 | DA | A | 2572 | --- | --- | --- | --- | 53.0 | 148.6 | C2'endo | 0.095 |
| 1 | DA | U | 2702 | --- | --- | --- | --- | 50.7 | 139.4 | C2'endo | 0.039 |
| 1 | DA | U | 2866 | --- | --- | --- | --- | 75.7 | 163.7 | C2'endo | 0.59 |