EMDataResource Pseudotorsion Plot Beta Server
RNA adopts complex three-dimensional folding patterns and has key roles in many cellular functions. Many cryoEM-derived structures contain RNA, including ribosomal particles, spliceosomes, RNA viruses, and polymerase complexes, yet procedures for validation of RNA structures are not as well developed as those for proteins.
This prototype web-service for virtual torsion angle validation of RNA structures can be applied to structures determined using cryo-EM as well as other structural methods. Virtual torsion angle plots for nucleic acids are analogous to Ramachandran plots for proteins. The tool evaluates single structures, either by file upload (mmCIF or PDB format) or by entering a PDB id.
The research community has developed simplified ways to represent nucleic acid backbone conformation through use of virtual torsion angles1-3. A common scheme is to define two virtual torsion angles (pseudotorsions), eta (η) and theta (θ) for a nucleotide triplet. The measured (η,θ) pair defines the backbone conformation relative to central residue (i).
The server calculates three varieties of pseudotorsion angles, as shown in the image below. In all definitions, phosphate atom positions are used, but the alternate atom differs: it is either the C4' atom (η,θ), C1' atom (η',θ'), or base origin4,5 position (η",θ").
Virtual torsion angles of the RNA backbone (calculated using DSSR4) are compared against the statistical distribution of a benchmark set of high quality, non-redundant6 RNA structures determined by X-ray crystallography at ≤ 2.5 Å. Separate analyses are performed based on sugar-puckering type (of ~27,000 residues in the benchmark set, ~24,000 are C3'-endo-like, ~3,000 are C2'-endo-like). Output plots and and a downloadable (csv format) table identify probable conformational outliers for any given RNA-containing structure. For comparison, RNA Suiteness7,8 scores are also provided in the csv (for residue i, suiteness of the i-1, i dinucleotide is listed. Suiteness range is 0(poor)-1(excellent). Calculation performed using DSSR).
The 2D plots permit comparison of pseudotorsion pairs for the structure being evaluated (plotted points) against population statistics of the benchmark set (smoothed contours: bar at right indicates benchmark residue count range). Outliers are marked on the plots by red crosses with residue information available on mouse hover. Summary statistics are provided below each plot to indicate the number of residues evaluated and percent outliers. Note that pseudotorsion angles cannot be calculated for terminal residues or around breaks in the polymer chain, so these are excluded from evaluation.
This tool is designed to identify regions of unusual conformation in folded RNA. Outliers can be legitimate but less-common backbone conformations, or they may indicate modelling error.
It may take several minutes to complete calculations for large structures such as ribosomes.
Please direct any questions/suggestions to help@emdataresource.org
- Olson, W. K. Configurational statistics of polynucleotide chains. An updated virtual bond model to treat effects of base stacking. Macromolecules 13, 721-728 (1980).
- Wadley, L. M., Keating, K. S., Duarte, C. M. & Pyle, A. M. Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol 372, 942-957, doi (2007).
- Keating, K. S., Humphris, E. L. & Pyle, A. M. A new way to see RNA. Q Rev Biophys 44, 433-466, doi (2011).
- Lu, X. J., Bussemaker, H. J. & Olson, W. K. DSSR: an integrated software tool for dissecting the spatial structure of RNA. Nucleic Acids Res 43, e142, doi (2015).
- Li, S., Olson, W. K., Lu, X. J. Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures. Nucleic Acids Research 47, W26-W34 (2019). doi
- Leontis, N. B., & Zirbel, C. L. Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking. In RNA 3D Structure Analysis and Prediction, N. Leontis & E. Westhof (Eds.), (Vol. 27, pp. 281-298). Springer Berlin Heidelberg. doi (2012).
- Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R.M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., Berman, H. M. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA 14, 465-81, doi (2008).
- Chen, V. B., Arendall III, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., Richardson, D. C., MolProbity: all-atom structure validation for macromolecular crystallography, Acta Cryst D 66, 12-21, doi (2010)
RNA Pseudotorsion Plots for PDB entry 4v64
Crystal structure of the bacterial ribosome from Escherichia coli in complex with hygromycin B. Deposited 2008-06-11 X-RAY DIFFRACTION resol 3.5 Å
7768 C3'-endo RNA residues with 159 outliers ( 2.05 % ) from Eta-Theta plot
1138 C2'-endo RNA residues with 115 outliers ( 10.11 % ) from Eta-Theta plot
7768 C3'-endo RNA residues with 155 outliers ( 2.0 % ) from Eta'-Theta' plot
1138 C2'-endo RNA residues with 99 outliers ( 8.7 % ) from Eta'-Theta' plot
7768 C3'-endo RNA residues with 132 outliers ( 1.7 % ) from Eta"-Theta" plot
1138 C2'-endo RNA residues with 87 outliers ( 7.64 % ) from Eta"-Theta" plot
List of Outliers
| Model Number | Chain | Residue Type | Residue Identifier | Eta | Theta | Eta' | Theta' | Eta'' | Theta'' | Sugar Pucker | Suiteness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | AA | A | 51 | 6.6 | 76.1 | 354.2 | 56.2 | 331.1 | 44.6 | C3'endo | 0.01 |
| 1 | AA | C | 183 | 39.7 | 275.4 | 74.3 | 266.9 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 209 | 27.7 | 70.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 247 | 259.0 | 133.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 250 | 217.0 | 115.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 266 | 13.4 | 89.9 | 341.5 | 88.3 | 328.7 | 44.9 | C3'endo | 0.0 |
| 1 | AA | C | 352 | 61.3 | 109.2 | 81.9 | 67.1 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 353 | 11.9 | 121.5 | 9.5 | 131.1 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 368 | 288.3 | 342.1 | --- | --- | --- | --- | C3'endo | 0.471 |
| 1 | AA | U | 421 | 58.5 | 1.6 | 71.8 | 331.5 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 461 | 213.9 | 283.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 466 | 99.3 | 119.0 | 90.9 | 139.7 | 63.5 | 172.2 | C3'endo | 0.0 |
| 1 | AA | U | 485 | 40.7 | 318.7 | 6.1 | 320.2 | 6.0 | 89.9 | C3'endo | 0.0 |
| 1 | AA | A | 563 | 106.0 | 107.5 | 103.3 | 85.0 | 102.5 | 28.4 | C3'endo | 0.599 |
| 1 | AA | U | 723 | 35.0 | 316.8 | 63.2 | 301.4 | --- | --- | C3'endo | 0.188 |
| 1 | AA | C | 754 | 109.3 | 309.7 | --- | --- | --- | --- | C3'endo | 0.708 |
| 1 | AA | G | 812 | 199.8 | 51.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 841 | 118.2 | 295.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 842 | 311.2 | 289.1 | 1.7 | 293.7 | --- | --- | C3'endo | 0.55 |
| 1 | AA | A | 845 | 77.9 | 290.2 | 82.2 | 290.7 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 975 | 44.6 | 54.1 | 26.6 | 60.1 | 60.3 | 78.5 | C3'endo | 0.0 |
| 1 | AA | U | 1030 | 81.7 | 27.4 | 77.5 | 343.2 | 125.0 | 329.0 | C3'endo | 0.0 |
| 1 | AA | C | 1054 | 9.4 | 132.0 | 4.1 | 117.0 | 21.1 | 54.0 | C3'endo | 0.0 |
| 1 | AA | A | 1167 | 11.4 | 159.9 | 30.4 | 145.0 | 13.1 | 117.4 | C3'endo | 0.0 |
| 1 | AA | U | 1183 | 329.5 | 12.1 | 334.2 | 320.2 | --- | --- | C3'endo | 0.698 |
| 1 | AA | U | 1212 | 328.2 | 81.1 | 342.9 | 45.7 | 159.9 | 21.2 | C3'endo | 0.0 |
| 1 | AA | A | 1225 | 205.6 | 284.6 | 238.2 | 276.6 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 1256 | 248.4 | 110.1 | 222.1 | 81.2 | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 1300 | 310.8 | 62.0 | 296.2 | 71.9 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1302 | 314.4 | 325.4 | 36.4 | 300.0 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1335 | 212.3 | 77.8 | --- | --- | --- | --- | C3'endo | 0.635 |
| 1 | AA | C | 1397 | 335.9 | 39.2 | 333.8 | 30.5 | --- | --- | C3'endo | 0.225 |
| 1 | AA | U | 1451 | 78.8 | 300.8 | 88.6 | 300.3 | --- | --- | C3'endo | 0.392 |
| 1 | AA | G | 1530 | 103.3 | 111.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 14 | 323.8 | 333.5 | 330.4 | 314.7 | 301.2 | 322.4 | C3'endo | 0.286 |
| 1 | BA | G | 41 | 290.4 | 338.6 | 336.2 | 316.0 | --- | --- | C3'endo | 0.18 |
| 1 | BB | A | 101 | 112.7 | 34.3 | 157.4 | 23.8 | 128.6 | 54.9 | C3'endo | 0.0 |
| 1 | BB | G | 248 | 125.7 | 309.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BB | G | 277 | 248.6 | 62.6 | 248.9 | 63.0 | --- | --- | C3'endo | 0.0 |
| 1 | BB | U | 405 | 44.6 | 315.4 | 6.5 | 349.1 | --- | --- | C3'endo | 0.047 |
| 1 | BB | A | 443 | 255.0 | 85.6 | 298.8 | 65.8 | 9.0 | 24.3 | C3'endo | 0.486 |
| 1 | BB | A | 480 | 114.5 | 300.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BB | A | 572 | 38.9 | 270.5 | --- | --- | --- | --- | C3'endo | 0.355 |
| 1 | BB | A | 751 | 295.4 | 97.7 | 321.6 | 115.7 | 328.8 | 129.9 | C3'endo | 0.775 |
| 1 | BB | A | 781 | 342.9 | 108.5 | 358.1 | 82.1 | 357.7 | 22.2 | C3'endo | 0.597 |
| 1 | BB | U | 827 | 346.1 | 57.7 | 350.9 | 46.9 | 326.7 | 60.8 | C3'endo | 0.0 |
| 1 | BB | U | 846 | 319.3 | 106.5 | 318.7 | 96.9 | 303.0 | 51.9 | C3'endo | 0.0 |
| 1 | BB | U | 958 | 284.7 | 104.7 | 325.3 | 81.5 | 355.5 | 48.1 | C3'endo | 0.278 |
| 1 | BB | A | 1175 | 273.8 | 317.3 | 281.4 | 316.8 | --- | --- | C3'endo | 0.174 |
| 1 | BB | C | 1211 | 342.8 | 32.3 | 18.8 | 13.6 | 84.3 | 359.5 | C3'endo | 0.0 |
| 1 | BB | U | 1255 | 260.7 | 15.5 | --- | --- | --- | --- | C3'endo | 0.539 |
| 1 | BB | U | 1273 | 340.1 | 144.1 | 42.0 | 116.1 | 68.4 | 84.0 | C3'endo | 0.068 |
| 1 | BB | U | 1584 | 294.1 | 340.2 | 287.8 | 330.3 | 162.0 | 330.2 | C3'endo | 0.0 |
| 1 | BB | A | 1757 | 352.2 | 331.1 | 353.9 | 310.1 | --- | --- | C3'endo | 0.114 |
| 1 | BB | C | 1965 | 280.9 | 333.8 | --- | --- | --- | --- | C3'endo | 0.094 |
| 1 | BB | A | 1969 | 213.4 | 85.5 | --- | --- | --- | --- | C3'endo | 0.453 |
| 1 | BB | U | 1971 | 15.9 | 341.7 | 355.0 | 336.1 | 354.7 | 320.3 | C3'endo | 0.0 |
| 1 | BB | A | 1981 | 299.8 | 286.7 | 353.1 | 283.9 | --- | --- | C3'endo | 0.276 |
| 1 | BB | U | 2068 | 268.3 | 39.3 | --- | --- | --- | --- | C3'endo | 0.494 |
| 1 | BB | A | 2147 | 244.5 | 34.6 | 269.0 | 25.4 | 294.9 | 18.4 | C3'endo | 0.0 |
| 1 | BB | U | 2203 | 51.3 | 103.2 | 49.6 | 77.5 | 77.0 | 349.6 | C3'endo | 0.0 |
| 1 | BB | A | 2211 | 75.9 | 263.1 | 24.4 | 286.9 | --- | --- | C3'endo | 0.0 |
| 1 | BB | U | 2320 | 218.7 | 91.2 | 220.5 | 68.4 | --- | --- | C3'endo | 0.01 |
| 1 | BB | U | 2321 | 105.9 | 333.0 | 120.6 | 305.5 | --- | --- | C3'endo | 0.0 |
| 1 | BB | C | 2424 | 93.4 | 346.9 | 74.9 | 327.4 | --- | --- | C3'endo | 0.057 |
| 1 | BB | G | 2428 | 290.7 | 96.8 | 273.9 | 92.1 | 191.0 | 72.7 | C3'endo | 0.11 |
| 1 | BB | C | 2440 | 348.7 | 279.1 | --- | --- | --- | --- | C3'endo | 0.145 |
| 1 | BB | G | 2502 | 356.8 | 34.8 | 18.6 | 39.7 | 126.2 | 58.5 | C3'endo | 0.0 |
| 1 | BB | G | 2505 | 336.2 | 147.8 | 345.2 | 140.3 | 333.9 | 130.8 | C3'endo | 0.0 |
| 1 | BB | G | 2732 | 223.4 | 306.2 | --- | --- | --- | --- | C3'endo | 0.03 |
| 1 | BB | U | 2790 | 206.3 | 66.4 | 230.7 | 42.1 | --- | --- | C3'endo | 0.0 |
| 1 | BB | G | 2867 | 345.2 | 42.6 | 286.4 | 102.1 | 290.2 | 96.9 | C3'endo | 0.0 |
| 1 | CA | C | 183 | 40.3 | 274.3 | 74.6 | 266.3 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 209 | 28.3 | 70.4 | 49.1 | 348.1 | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 247 | 257.9 | 132.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 250 | 216.2 | 115.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 266 | 13.4 | 89.6 | 341.8 | 87.7 | 328.7 | 44.7 | C3'endo | 0.0 |
| 1 | CA | C | 352 | 60.5 | 110.2 | 81.2 | 67.8 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 353 | 11.4 | 121.0 | 9.1 | 130.3 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 368 | 287.7 | 342.0 | --- | --- | --- | --- | C3'endo | 0.467 |
| 1 | CA | U | 421 | 59.3 | 0.4 | 72.0 | 330.8 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 461 | 213.1 | 283.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 466 | 98.9 | 118.1 | 90.8 | 139.5 | 63.2 | 172.1 | C3'endo | 0.0 |
| 1 | CA | U | 485 | 41.1 | 318.0 | 6.5 | 319.2 | 6.0 | 89.6 | C3'endo | 0.0 |
| 1 | CA | G | 530 | 198.4 | 54.9 | --- | --- | --- | --- | C3'endo | 0.232 |
| 1 | CA | A | 563 | 105.7 | 107.7 | 103.1 | 85.1 | 102.7 | 28.8 | C3'endo | 0.602 |
| 1 | CA | U | 723 | 36.1 | 315.8 | 63.3 | 300.6 | --- | --- | C3'endo | 0.196 |
| 1 | CA | C | 754 | 108.5 | 309.6 | --- | --- | --- | --- | C3'endo | 0.628 |
| 1 | CA | G | 812 | 199.2 | 52.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 841 | 117.6 | 295.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 842 | 311.1 | 288.9 | 1.5 | 293.4 | --- | --- | C3'endo | 0.557 |
| 1 | CA | A | 845 | 77.8 | 290.4 | 82.0 | 290.9 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 975 | 43.3 | 55.5 | 25.7 | 60.6 | 59.5 | 78.6 | C3'endo | 0.0 |
| 1 | CA | U | 1030 | 81.7 | 28.0 | 77.3 | 343.5 | 124.8 | 329.3 | C3'endo | 0.0 |
| 1 | CA | C | 1054 | 9.0 | 131.3 | 3.8 | 116.2 | 21.2 | 52.4 | C3'endo | 0.0 |
| 1 | CA | A | 1167 | 11.5 | 159.7 | 30.5 | 145.2 | 13.6 | 117.8 | C3'endo | 0.0 |
| 1 | CA | U | 1183 | 329.6 | 11.8 | 334.0 | 320.3 | --- | --- | C3'endo | 0.706 |
| 1 | CA | U | 1212 | 329.2 | 83.0 | 344.3 | 46.1 | 159.5 | 21.3 | C3'endo | 0.0 |
| 1 | CA | A | 1225 | 205.5 | 284.8 | 238.0 | 276.6 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1256 | 249.1 | 109.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 1300 | 310.0 | 62.4 | 296.4 | 71.9 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 1302 | 315.1 | 325.3 | 36.2 | 299.6 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1335 | 213.0 | 78.1 | --- | --- | --- | --- | C3'endo | 0.611 |
| 1 | CA | C | 1397 | 337.6 | 38.1 | 334.9 | 29.8 | --- | --- | C3'endo | 0.178 |
| 1 | CA | U | 1451 | 77.5 | 301.5 | 87.8 | 300.5 | --- | --- | C3'endo | 0.438 |
| 1 | CA | G | 1530 | 103.7 | 111.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 14 | 323.2 | 334.1 | 330.0 | 315.0 | 300.8 | 321.9 | C3'endo | 0.295 |
| 1 | DA | G | 41 | 290.8 | 337.8 | 336.1 | 316.0 | --- | --- | C3'endo | 0.178 |
| 1 | DB | U | 102 | 314.7 | 95.9 | 129.5 | 35.9 | 136.1 | 8.8 | C3'endo | 0.0 |
| 1 | DB | A | 125 | 102.5 | 314.3 | 80.2 | 286.4 | 51.8 | 179.0 | C3'endo | 0.0 |
| 1 | DB | G | 248 | 125.7 | 309.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DB | G | 277 | 288.9 | 102.1 | 276.4 | 86.3 | --- | --- | C3'endo | 0.0 |
| 1 | DB | U | 405 | 45.6 | 313.9 | 7.5 | 347.7 | --- | --- | C3'endo | 0.036 |
| 1 | DB | A | 443 | 254.0 | 86.3 | 298.1 | 66.5 | 8.4 | 24.9 | C3'endo | 0.485 |
| 1 | DB | A | 480 | 114.1 | 300.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DB | A | 572 | 39.9 | 270.1 | --- | --- | --- | --- | C3'endo | 0.362 |
| 1 | DB | A | 751 | 296.2 | 97.7 | 322.3 | 115.3 | 329.1 | 130.2 | C3'endo | 0.717 |
| 1 | DB | A | 781 | 342.7 | 108.4 | 357.7 | 82.4 | 356.8 | 22.5 | C3'endo | 0.602 |
| 1 | DB | U | 827 | 346.9 | 56.7 | 351.2 | 47.1 | 327.5 | 61.3 | C3'endo | 0.0 |
| 1 | DB | U | 846 | 318.8 | 106.4 | 318.5 | 96.7 | 303.0 | 51.9 | C3'endo | 0.0 |
| 1 | DB | U | 958 | 283.6 | 105.6 | 324.8 | 82.7 | 355.2 | 49.0 | C3'endo | 0.207 |
| 1 | DB | A | 1175 | 47.3 | 275.1 | 55.9 | 278.7 | --- | --- | C3'endo | 0.347 |
| 1 | DB | C | 1211 | 343.8 | 31.6 | 19.5 | 13.4 | 84.4 | 359.5 | C3'endo | 0.0 |
| 1 | DB | U | 1273 | 340.5 | 144.3 | 41.4 | 117.0 | 68.5 | 85.4 | C3'endo | 0.051 |
| 1 | DB | U | 1584 | 294.9 | 339.9 | 288.9 | 330.2 | 162.0 | 330.7 | C3'endo | 0.0 |
| 1 | DB | A | 1757 | 351.7 | 331.9 | 353.2 | 310.8 | --- | --- | C3'endo | 0.111 |
| 1 | DB | C | 1965 | 280.7 | 333.9 | --- | --- | --- | --- | C3'endo | 0.098 |
| 1 | DB | A | 1969 | 214.2 | 87.3 | --- | --- | --- | --- | C3'endo | 0.455 |
| 1 | DB | U | 1971 | 16.2 | 341.2 | 355.9 | 335.5 | 356.3 | 318.4 | C3'endo | 0.0 |
| 1 | DB | A | 1981 | 300.2 | 286.4 | 353.5 | 283.6 | --- | --- | C3'endo | 0.305 |
| 1 | DB | C | 2055 | 235.1 | 50.5 | 259.9 | 62.3 | 305.3 | 121.1 | C3'endo | 0.0 |
| 1 | DB | U | 2068 | 267.8 | 39.8 | --- | --- | --- | --- | C3'endo | 0.501 |
| 1 | DB | A | 2108 | 103.5 | 34.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DB | A | 2134 | 109.3 | 129.3 | 93.5 | 148.4 | --- | --- | C3'endo | 0.01 |
| 1 | DB | C | 2145 | 306.2 | 291.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DB | U | 2203 | 51.9 | 104.3 | 49.3 | 81.2 | 75.1 | 349.9 | C3'endo | 0.0 |
| 1 | DB | A | 2211 | 74.8 | 265.7 | 23.7 | 289.1 | --- | --- | C3'endo | 0.0 |
| 1 | DB | U | 2320 | 219.1 | 93.7 | 220.7 | 70.2 | --- | --- | C3'endo | 0.01 |
| 1 | DB | U | 2321 | 103.0 | 331.2 | 116.5 | 303.8 | --- | --- | C3'endo | 0.0 |
| 1 | DB | C | 2424 | 93.7 | 347.1 | 75.5 | 327.4 | --- | --- | C3'endo | 0.068 |
| 1 | DB | G | 2428 | 291.0 | 96.7 | 274.1 | 92.4 | 190.6 | 72.9 | C3'endo | 0.118 |
| 1 | DB | C | 2440 | 348.6 | 279.6 | --- | --- | --- | --- | C3'endo | 0.107 |
| 1 | DB | U | 2473 | 285.9 | 279.7 | --- | --- | --- | --- | C3'endo | 0.609 |
| 1 | DB | G | 2502 | 357.9 | 34.2 | 20.1 | 39.5 | 127.1 | 57.8 | C3'endo | 0.0 |
| 1 | DB | G | 2505 | 335.5 | 148.3 | 344.4 | 140.8 | 333.9 | 131.0 | C3'endo | 0.0 |
| 1 | DB | G | 2732 | 223.2 | 305.7 | --- | --- | --- | --- | C3'endo | 0.021 |
| 1 | DB | U | 2790 | 206.8 | 62.3 | 232.3 | 36.9 | --- | --- | C3'endo | 0.0 |
| 1 | DB | G | 2867 | 346.3 | 41.2 | 286.8 | 101.8 | 290.0 | 97.1 | C3'endo | 0.0 |
| 1 | AA | A | 397 | --- | --- | 308.4 | 129.4 | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 413 | --- | --- | 141.3 | 74.6 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 465 | --- | --- | 47.2 | 142.7 | 26.3 | 77.6 | C3'endo | 0.0 |
| 1 | AA | U | 467 | --- | --- | 145.0 | 341.6 | 163.4 | 332.6 | C3'endo | 0.0 |
| 1 | AA | U | 632 | --- | --- | 232.5 | 343.1 | --- | --- | C3'endo | 0.295 |
| 1 | AA | U | 843 | --- | --- | 324.4 | 289.1 | 339.0 | 320.4 | C3'endo | 0.0 |
| 1 | AA | A | 1285 | --- | --- | 97.2 | 109.5 | 115.2 | 343.2 | C3'endo | 0.0 |
| 1 | BA | U | 25 | --- | --- | 268.0 | 103.8 | --- | --- | C3'endo | 0.032 |
| 1 | BA | A | 66 | --- | --- | 242.0 | 123.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 89 | --- | --- | 140.4 | 325.0 | 158.1 | 347.0 | C3'endo | 0.673 |
| 1 | BB | G | 549 | --- | --- | 156.7 | 10.3 | 140.3 | 20.3 | C3'endo | 0.0 |
| 1 | BB | U | 562 | --- | --- | 293.4 | 149.5 | --- | --- | C3'endo | 0.423 |
| 1 | BB | A | 1583 | --- | --- | 236.6 | 148.9 | --- | --- | C3'endo | 0.0 |
| 1 | BB | G | 1756 | --- | --- | 236.1 | 147.3 | --- | --- | C3'endo | 0.0 |
| 1 | BB | U | 1779 | --- | --- | 156.6 | 19.7 | 126.6 | 27.4 | C3'endo | 0.193 |
| 1 | BB | A | 1785 | --- | --- | 108.5 | 142.3 | 122.1 | 102.6 | C3'endo | 0.576 |
| 1 | BB | G | 1930 | --- | --- | 137.0 | 83.9 | 128.5 | 99.4 | C3'endo | 0.0 |
| 1 | BB | A | 2134 | --- | --- | 105.8 | 144.7 | --- | --- | C3'endo | 0.219 |
| 1 | BB | A | 2267 | --- | --- | 141.8 | 57.8 | --- | --- | C3'endo | 0.082 |
| 1 | BB | U | 2402 | --- | --- | 278.2 | 136.5 | 297.7 | 104.3 | C3'endo | 0.0 |
| 1 | BB | C | 2573 | --- | --- | 259.0 | 52.1 | --- | --- | C3'endo | 0.0 |
| 1 | BB | A | 2577 | --- | --- | 287.5 | 3.0 | --- | --- | C3'endo | 0.016 |
| 1 | BB | C | 2755 | --- | --- | 344.6 | 150.7 | --- | --- | C3'endo | 0.581 |
| 1 | BB | G | 2777 | --- | --- | 320.8 | 66.4 | --- | --- | C3'endo | 0.196 |
| 1 | CA | A | 397 | --- | --- | 308.3 | 129.6 | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 413 | --- | --- | 142.0 | 74.0 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 465 | --- | --- | 47.7 | 143.5 | 27.1 | 77.9 | C3'endo | 0.0 |
| 1 | CA | U | 467 | --- | --- | 144.9 | 341.8 | 163.3 | 332.6 | C3'endo | 0.0 |
| 1 | CA | U | 632 | --- | --- | 231.9 | 342.5 | --- | --- | C3'endo | 0.33 |
| 1 | CA | U | 843 | --- | --- | 324.5 | 288.8 | 339.1 | 320.4 | C3'endo | 0.0 |
| 1 | CA | A | 1285 | --- | --- | 97.2 | 109.5 | 114.8 | 340.4 | C3'endo | 0.0 |
| 1 | DA | U | 25 | --- | --- | 268.5 | 103.0 | --- | --- | C3'endo | 0.031 |
| 1 | DA | A | 66 | --- | --- | 242.8 | 124.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 89 | --- | --- | 139.9 | 325.7 | 157.7 | 347.3 | C3'endo | 0.671 |
| 1 | DB | G | 549 | --- | --- | 136.6 | 359.0 | 113.2 | 32.0 | C3'endo | 0.0 |
| 1 | DB | U | 562 | --- | --- | 292.7 | 149.3 | --- | --- | C3'endo | 0.42 |
| 1 | DB | U | 1176 | --- | --- | 310.8 | 154.4 | 335.2 | 173.6 | C3'endo | 0.0 |
| 1 | DB | A | 1583 | --- | --- | 235.8 | 147.4 | --- | --- | C3'endo | 0.0 |
| 1 | DB | G | 1756 | --- | --- | 236.8 | 148.0 | --- | --- | C3'endo | 0.0 |
| 1 | DB | U | 1779 | --- | --- | 155.6 | 19.8 | 126.5 | 27.5 | C3'endo | 0.189 |
| 1 | DB | A | 1785 | --- | --- | 108.8 | 142.8 | 122.4 | 103.0 | C3'endo | 0.592 |
| 1 | DB | G | 1930 | --- | --- | 137.0 | 84.1 | 128.4 | 99.1 | C3'endo | 0.0 |
| 1 | DB | G | 2148 | --- | --- | 150.9 | 112.7 | --- | --- | C3'endo | 0.249 |
| 1 | DB | A | 2267 | --- | --- | 141.8 | 58.1 | --- | --- | C3'endo | 0.075 |
| 1 | DB | U | 2402 | --- | --- | 278.2 | 137.3 | 298.0 | 104.5 | C3'endo | 0.0 |
| 1 | DB | C | 2573 | --- | --- | 257.9 | 52.4 | --- | --- | C3'endo | 0.0 |
| 1 | DB | A | 2577 | --- | --- | 287.2 | 2.4 | --- | --- | C3'endo | 0.011 |
| 1 | DB | G | 2777 | --- | --- | 320.6 | 66.7 | --- | --- | C3'endo | 0.208 |
| 1 | AA | A | 279 | --- | --- | --- | --- | 141.2 | 329.4 | C3'endo | 0.244 |
| 1 | AA | A | 665 | --- | --- | --- | --- | 17.5 | 158.4 | C3'endo | 0.0 |
| 1 | AA | G | 722 | --- | --- | --- | --- | 160.9 | 75.0 | C3'endo | 0.552 |
| 1 | AA | U | 1029 | --- | --- | --- | --- | 291.5 | 10.8 | C3'endo | 0.37 |
| 1 | AA | G | 1138 | --- | --- | --- | --- | 100.6 | 183.0 | C3'endo | 0.0 |
| 1 | AA | A | 1377 | --- | --- | --- | --- | 175.6 | 86.0 | C3'endo | 0.826 |
| 1 | BB | U | 162 | --- | --- | --- | --- | 128.7 | 98.3 | C3'endo | 0.0 |
| 1 | BB | G | 548 | --- | --- | --- | --- | 284.5 | 90.8 | C3'endo | 0.0 |
| 1 | BB | U | 653 | --- | --- | --- | --- | 175.4 | 332.3 | C3'endo | 0.095 |
| 1 | BB | U | 747 | 354.6 | 1.6 | --- | --- | 116.5 | 357.3 | C3'endo | 0.0 |
| 1 | BB | G | 763 | --- | --- | --- | --- | 109.3 | 119.7 | C3'endo | 0.602 |
| 1 | BB | U | 931 | 16.9 | 310.9 | --- | --- | 20.0 | 76.8 | C3'endo | 0.0 |
| 1 | BB | C | 1135 | --- | --- | --- | --- | 354.4 | 195.3 | C3'endo | 0.0 |
| 1 | BB | G | 1210 | --- | --- | --- | --- | 139.6 | 330.4 | C3'endo | 0.01 |
| 1 | BB | A | 1274 | --- | --- | --- | --- | 1.2 | 149.4 | C3'endo | 0.01 |
| 1 | BB | U | 1340 | 208.6 | 310.4 | --- | --- | 181.0 | 3.0 | C3'endo | 0.214 |
| 1 | BB | C | 1646 | --- | --- | --- | --- | 193.4 | 53.5 | C3'endo | 0.473 |
| 1 | BB | A | 1700 | --- | --- | --- | --- | 324.5 | 292.4 | C3'endo | 0.0 |
| 1 | BB | C | 1730 | --- | --- | --- | --- | 321.1 | 124.0 | C3'endo | 0.0 |
| 1 | BB | C | 1816 | 312.0 | 16.3 | --- | --- | 284.1 | 82.6 | C3'endo | 0.0 |
| 1 | BB | C | 2055 | 235.7 | 50.5 | --- | --- | 306.7 | 122.0 | C3'endo | 0.0 |
| 1 | BB | C | 2104 | --- | --- | --- | --- | 294.4 | 125.6 | C3'endo | 0.0 |
| 1 | BB | C | 2145 | 294.6 | 309.6 | --- | --- | 1.2 | 200.0 | C3'endo | 0.0 |
| 1 | BB | A | 2335 | --- | --- | --- | --- | 290.4 | 107.1 | C3'endo | 0.0 |
| 1 | BB | G | 2529 | 45.0 | 52.5 | --- | --- | 35.3 | 337.8 | C3'endo | 0.0 |
| 1 | BB | A | 2883 | --- | --- | --- | --- | 185.4 | 47.6 | C3'endo | 0.0 |
| 1 | CA | A | 279 | --- | --- | --- | --- | 141.2 | 328.8 | C3'endo | 0.223 |
| 1 | CA | A | 665 | --- | --- | --- | --- | 18.1 | 159.6 | C3'endo | 0.0 |
| 1 | CA | G | 722 | --- | --- | --- | --- | 160.8 | 74.5 | C3'endo | 0.564 |
| 1 | CA | U | 1029 | --- | --- | --- | --- | 291.5 | 10.7 | C3'endo | 0.344 |
| 1 | CA | G | 1138 | --- | --- | --- | --- | 101.4 | 183.3 | C3'endo | 0.0 |
| 1 | CA | A | 1377 | --- | --- | --- | --- | 176.4 | 85.8 | C3'endo | 0.833 |
| 1 | CA | G | 1505 | --- | --- | --- | --- | 175.9 | 8.9 | C3'endo | 0.049 |
| 1 | DB | A | 127 | --- | --- | --- | --- | 174.7 | 41.1 | C3'endo | 0.666 |
| 1 | DB | U | 138 | --- | --- | --- | --- | 285.0 | 50.7 | C3'endo | 0.439 |
| 1 | DB | C | 140 | --- | --- | --- | --- | 189.5 | 45.7 | C3'endo | 0.0 |
| 1 | DB | U | 162 | --- | --- | --- | --- | 127.8 | 98.6 | C3'endo | 0.0 |
| 1 | DB | A | 278 | --- | --- | --- | --- | 75.4 | 178.6 | C3'endo | 0.0 |
| 1 | DB | U | 653 | --- | --- | --- | --- | 175.6 | 332.0 | C3'endo | 0.082 |
| 1 | DB | U | 747 | 354.5 | 2.0 | --- | --- | 115.9 | 356.5 | C3'endo | 0.0 |
| 1 | DB | G | 763 | --- | --- | --- | --- | 110.1 | 119.8 | C3'endo | 0.518 |
| 1 | DB | U | 931 | 17.6 | 310.0 | --- | --- | 19.3 | 80.8 | C3'endo | 0.0 |
| 1 | DB | C | 1135 | --- | --- | --- | --- | 353.7 | 195.1 | C3'endo | 0.0 |
| 1 | DB | G | 1210 | --- | --- | --- | --- | 139.8 | 330.7 | C3'endo | 0.01 |
| 1 | DB | A | 1274 | --- | --- | --- | --- | 0.6 | 149.8 | C3'endo | 0.01 |
| 1 | DB | U | 1340 | 208.5 | 311.0 | --- | --- | 180.4 | 3.6 | C3'endo | 0.213 |
| 1 | DB | C | 1646 | --- | --- | --- | --- | 193.1 | 54.0 | C3'endo | 0.48 |
| 1 | DB | A | 1700 | --- | --- | --- | --- | 324.8 | 292.6 | C3'endo | 0.0 |
| 1 | DB | C | 1730 | --- | --- | --- | --- | 321.0 | 123.8 | C3'endo | 0.0 |
| 1 | DB | C | 1816 | 312.8 | 15.2 | --- | --- | 284.2 | 82.3 | C3'endo | 0.0 |
| 1 | DB | C | 2104 | --- | --- | --- | --- | 295.2 | 141.4 | C3'endo | 0.354 |
| 1 | DB | A | 2335 | --- | --- | --- | --- | 289.6 | 106.6 | C3'endo | 0.0 |
| 1 | DB | G | 2529 | --- | --- | --- | --- | 35.3 | 337.4 | C3'endo | 0.0 |
| 1 | DB | C | 2755 | --- | --- | --- | --- | 356.3 | 99.3 | C3'endo | 0.303 |
| 1 | DB | A | 2883 | --- | --- | --- | --- | 185.4 | 48.2 | C3'endo | 0.0 |
| 1 | AA | A | 60 | 301.1 | 175.9 | 38.7 | 142.5 | --- | --- | C2'endo | 0.091 |
| 1 | AA | G | 86 | 236.6 | 20.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 88 | 272.7 | 215.2 | 293.9 | 197.5 | --- | --- | C2'endo | 0.0 |
| 1 | AA | C | 210 | 125.7 | 83.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 244 | 23.2 | 66.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 533 | 349.5 | 242.6 | 39.9 | 207.2 | --- | --- | C2'endo | 0.225 |
| 1 | AA | A | 815 | 62.3 | 32.5 | 48.4 | 12.0 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 820 | 163.9 | 1.6 | --- | --- | --- | --- | C2'endo | 0.505 |
| 1 | AA | U | 960 | 276.2 | 359.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 974 | 76.4 | 69.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | C | 1031 | 161.7 | 34.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 1094 | 12.9 | 69.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 1211 | 214.0 | 21.3 | --- | --- | --- | --- | C2'endo | 0.6 |
| 1 | AA | A | 1319 | 250.0 | 181.0 | --- | --- | --- | --- | C2'endo | 0.171 |
| 1 | BA | A | 15 | 147.8 | 289.6 | --- | --- | --- | --- | C2'endo | 0.051 |
| 1 | BA | C | 88 | 318.0 | 229.7 | 10.6 | 190.1 | 343.2 | 197.5 | C2'endo | 0.0 |
| 1 | BB | U | 139 | 1.7 | 58.1 | 27.0 | 21.6 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 222 | 279.6 | 229.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 271 | 88.5 | 145.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 330 | 83.2 | 246.5 | 134.2 | 203.0 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 370 | 221.1 | 358.3 | --- | --- | --- | --- | C2'endo | 0.404 |
| 1 | BB | G | 481 | 156.9 | 44.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 504 | 7.7 | 52.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 529 | 260.9 | 172.3 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BB | A | 532 | 138.3 | 34.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | U | 573 | 252.4 | 191.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 574 | 22.4 | 80.2 | 68.7 | 42.0 | --- | --- | C2'endo | 0.01 |
| 1 | BB | U | 615 | 280.8 | 346.9 | 281.9 | 328.6 | --- | --- | C2'endo | 0.0 |
| 1 | BB | C | 645 | 136.7 | 330.8 | 125.8 | 304.8 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 655 | 278.4 | 182.2 | 326.3 | 160.0 | 317.2 | 219.3 | C2'endo | 0.0 |
| 1 | BB | G | 859 | 130.7 | 164.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 945 | 109.0 | 223.5 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BB | G | 974 | 83.4 | 81.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 1025 | 28.4 | 72.0 | 104.4 | 45.5 | --- | --- | C2'endo | 0.0 |
| 1 | BB | U | 1033 | 39.4 | 219.1 | 24.5 | 191.4 | 342.2 | 127.2 | C2'endo | 0.0 |
| 1 | BB | A | 1070 | 122.8 | 7.9 | 121.3 | 325.5 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 1134 | 299.4 | 150.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 1252 | 332.9 | 245.1 | --- | --- | --- | --- | C2'endo | 0.347 |
| 1 | BB | A | 1453 | 254.0 | 284.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | C | 1558 | 86.5 | 96.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 1609 | 333.6 | 250.1 | --- | --- | --- | --- | C2'endo | 0.28 |
| 1 | BB | G | 1715 | 295.0 | 149.4 | 50.7 | 91.9 | 71.0 | 115.7 | C2'endo | 0.0 |
| 1 | BB | A | 1938 | 14.0 | 255.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 1992 | 304.6 | 146.0 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BB | A | 2030 | 33.5 | 59.1 | --- | --- | --- | --- | C2'endo | 0.023 |
| 1 | BB | A | 2031 | 138.4 | 79.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | C | 2146 | 270.4 | 272.7 | 41.5 | 229.4 | --- | --- | C2'endo | 0.428 |
| 1 | BB | A | 2198 | 102.8 | 201.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 2266 | 84.1 | 47.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 2346 | 332.5 | 35.3 | --- | --- | --- | --- | C2'endo | 0.645 |
| 1 | BB | U | 2423 | 22.0 | 53.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | U | 2491 | 116.0 | 180.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BB | U | 2689 | 131.7 | 345.9 | 144.4 | 299.9 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 60 | 322.9 | 157.9 | 41.9 | 138.5 | --- | --- | C2'endo | 0.081 |
| 1 | CA | C | 210 | 124.5 | 84.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 244 | 22.9 | 66.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 533 | 352.0 | 242.0 | 40.7 | 208.2 | --- | --- | C2'endo | 0.265 |
| 1 | CA | A | 815 | 62.4 | 32.6 | 48.5 | 12.2 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 820 | 164.1 | 2.0 | --- | --- | --- | --- | C2'endo | 0.51 |
| 1 | CA | U | 960 | 276.4 | 358.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 974 | 74.8 | 71.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 1031 | 160.6 | 35.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | G | 1094 | 12.6 | 69.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1211 | 215.4 | 20.9 | --- | --- | --- | --- | C2'endo | 0.589 |
| 1 | CA | A | 1319 | 248.8 | 178.9 | --- | --- | --- | --- | C2'endo | 0.222 |
| 1 | DA | A | 15 | 147.2 | 289.0 | --- | --- | --- | --- | C2'endo | 0.041 |
| 1 | DA | C | 88 | 317.8 | 229.5 | 10.4 | 189.7 | 343.0 | 196.9 | C2'endo | 0.0 |
| 1 | DB | U | 100 | 278.1 | 353.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 139 | 30.8 | 47.8 | 43.2 | 5.6 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 222 | 278.7 | 230.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 330 | 82.2 | 247.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 370 | 221.2 | 358.1 | --- | --- | --- | --- | C2'endo | 0.39 |
| 1 | DB | A | 454 | 281.9 | 339.7 | --- | --- | --- | --- | C2'endo | 0.102 |
| 1 | DB | G | 481 | 157.3 | 44.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 504 | 7.5 | 53.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 532 | 138.1 | 35.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 573 | 251.8 | 192.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 574 | 22.7 | 80.2 | 68.5 | 42.2 | --- | --- | C2'endo | 0.015 |
| 1 | DB | U | 615 | 281.8 | 345.7 | 282.3 | 328.5 | --- | --- | C2'endo | 0.0 |
| 1 | DB | C | 645 | 137.0 | 331.3 | 126.1 | 304.8 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 655 | 278.9 | 181.6 | 326.9 | 159.6 | 317.2 | 219.0 | C2'endo | 0.0 |
| 1 | DB | G | 859 | 133.6 | 162.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 945 | 108.0 | 223.2 | --- | --- | --- | --- | C2'endo | 0.034 |
| 1 | DB | G | 974 | 82.3 | 81.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 1025 | 27.0 | 72.7 | 104.5 | 44.3 | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 1033 | 38.0 | 217.4 | 23.7 | 190.5 | 341.8 | 127.0 | C2'endo | 0.0 |
| 1 | DB | A | 1070 | 123.4 | 7.7 | 121.5 | 325.4 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 1134 | 300.6 | 150.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 1252 | 332.5 | 245.9 | --- | --- | --- | --- | C2'endo | 0.355 |
| 1 | DB | A | 1453 | 254.5 | 284.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | C | 1558 | 87.8 | 95.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 1609 | 333.6 | 249.8 | --- | --- | --- | --- | C2'endo | 0.275 |
| 1 | DB | A | 1913 | 131.5 | 173.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 1992 | 305.3 | 146.0 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DB | A | 2030 | 34.6 | 58.8 | 29.6 | 60.1 | --- | --- | C2'endo | 0.024 |
| 1 | DB | A | 2031 | 138.5 | 77.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | C | 2146 | 315.4 | 171.0 | 23.3 | 165.0 | 25.1 | 196.6 | C2'endo | 0.199 |
| 1 | DB | A | 2147 | 278.6 | 43.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 2198 | 103.9 | 203.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 2266 | 82.4 | 48.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 2346 | 332.5 | 35.2 | --- | --- | --- | --- | C2'endo | 0.636 |
| 1 | DB | U | 2423 | 22.3 | 53.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 2491 | 116.5 | 180.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 2689 | 132.2 | 346.1 | 145.0 | 300.1 | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 2751 | 286.9 | 290.5 | --- | --- | --- | --- | C2'endo | 0.05 |
| 1 | AA | A | 8 | --- | --- | 288.9 | 241.4 | 302.0 | 261.5 | C2'endo | 0.013 |
| 1 | AA | A | 50 | --- | --- | 78.1 | 101.8 | 85.4 | 112.6 | C2'endo | 0.177 |
| 1 | AA | U | 85 | --- | --- | 284.9 | 120.0 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 451 | --- | --- | 78.0 | 87.2 | --- | --- | C2'endo | 0.154 |
| 1 | AA | A | 532 | --- | --- | 288.7 | 207.9 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 1101 | --- | --- | 342.4 | 121.2 | 319.9 | 157.9 | C2'endo | 0.0 |
| 1 | AA | U | 1125 | --- | --- | 164.7 | 201.0 | --- | --- | C2'endo | 0.418 |
| 1 | AA | A | 1201 | --- | --- | 40.8 | 89.9 | 67.8 | 86.3 | C2'endo | 0.1 |
| 1 | BB | U | 100 | --- | --- | 313.6 | 257.3 | --- | --- | C2'endo | 0.0 |
| 1 | BB | C | 140 | --- | --- | 196.0 | 345.2 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 196 | --- | --- | 313.9 | 257.4 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 329 | --- | --- | 49.8 | 238.7 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 386 | --- | --- | 129.7 | 328.6 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 457 | --- | --- | 16.8 | 136.8 | --- | --- | C2'endo | 0.0 |
| 1 | BB | C | 531 | --- | --- | 163.0 | 52.4 | 148.0 | 36.3 | C2'endo | 0.0 |
| 1 | BB | U | 546 | --- | --- | 348.4 | 156.5 | 326.9 | 194.9 | C2'endo | 0.0 |
| 1 | BB | A | 627 | --- | --- | 63.7 | 141.6 | --- | --- | C2'endo | 0.0 |
| 1 | BB | U | 746 | --- | --- | 209.5 | 0.8 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 789 | --- | --- | 266.2 | 308.2 | --- | --- | C2'endo | 0.0 |
| 1 | BB | U | 1132 | --- | --- | 166.6 | 287.7 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 1205 | --- | --- | 339.8 | 345.6 | 352.2 | 22.2 | C2'endo | 0.0 |
| 1 | BB | U | 1325 | --- | --- | 338.6 | 246.8 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 1383 | --- | --- | 157.6 | 192.8 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 1416 | --- | --- | 329.4 | 155.4 | --- | --- | C2'endo | 0.0 |
| 1 | BB | U | 1460 | --- | --- | 186.5 | 353.0 | 164.8 | 22.5 | C2'endo | 0.0 |
| 1 | BB | A | 1608 | --- | --- | 172.7 | 198.3 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 1731 | --- | --- | 164.2 | 128.2 | --- | --- | C2'endo | 0.01 |
| 1 | BB | U | 1758 | --- | --- | 284.2 | 259.1 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 2032 | --- | --- | 326.2 | 273.0 | --- | --- | C2'endo | 0.037 |
| 1 | BB | A | 2033 | --- | --- | 279.1 | 197.1 | --- | --- | C2'endo | 0.095 |
| 1 | BB | A | 2060 | --- | --- | 324.8 | 135.4 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 2391 | --- | --- | 175.1 | 121.9 | --- | --- | C2'endo | 0.436 |
| 1 | BB | U | 2690 | --- | --- | 148.9 | 259.2 | 160.2 | 295.3 | C2'endo | 0.0 |
| 1 | BB | A | 2872 | --- | --- | 152.6 | 188.6 | --- | --- | C2'endo | 0.0 |
| 1 | BB | A | 2873 | --- | --- | 144.8 | 277.4 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 8 | --- | --- | 287.4 | 241.6 | 301.6 | 261.7 | C2'endo | 0.011 |
| 1 | CA | A | 50 | --- | --- | 78.0 | 100.6 | 86.0 | 112.4 | C2'endo | 0.152 |
| 1 | CA | A | 451 | --- | --- | 78.2 | 87.3 | --- | --- | C2'endo | 0.171 |
| 1 | CA | A | 532 | --- | --- | 288.4 | 207.6 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1101 | --- | --- | 341.9 | 122.4 | 320.0 | 158.8 | C2'endo | 0.0 |
| 1 | CA | U | 1125 | --- | --- | 164.8 | 201.2 | --- | --- | C2'endo | 0.438 |
| 1 | CA | A | 1201 | --- | --- | 40.2 | 89.5 | 67.8 | 85.3 | C2'endo | 0.127 |
| 1 | DB | A | 196 | --- | --- | 314.3 | 259.2 | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 329 | --- | --- | 49.4 | 239.4 | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 386 | --- | --- | 129.0 | 331.0 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 457 | --- | --- | 17.1 | 136.9 | --- | --- | C2'endo | 0.0 |
| 1 | DB | C | 531 | --- | --- | 161.5 | 51.6 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 627 | --- | --- | 63.3 | 141.7 | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 746 | --- | --- | 209.7 | 0.1 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 789 | --- | --- | 264.7 | 308.1 | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 1132 | --- | --- | 166.6 | 287.3 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 1205 | --- | --- | 339.4 | 346.1 | 351.7 | 22.5 | C2'endo | 0.0 |
| 1 | DB | U | 1325 | --- | --- | 339.1 | 246.2 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 1383 | --- | --- | 158.6 | 193.3 | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 1416 | --- | --- | 329.2 | 155.2 | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 1460 | --- | --- | 187.0 | 352.7 | 165.2 | 22.4 | C2'endo | 0.0 |
| 1 | DB | A | 1608 | --- | --- | 172.3 | 197.4 | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 1715 | --- | --- | 50.5 | 91.9 | 71.3 | 115.5 | C2'endo | 0.0 |
| 1 | DB | G | 1731 | --- | --- | 163.7 | 128.0 | --- | --- | C2'endo | 0.01 |
| 1 | DB | U | 1758 | --- | --- | 283.7 | 258.8 | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 2032 | --- | --- | 330.0 | 271.0 | --- | --- | C2'endo | 0.022 |
| 1 | DB | A | 2033 | --- | --- | 280.0 | 196.2 | --- | --- | C2'endo | 0.055 |
| 1 | DB | A | 2060 | --- | --- | 324.8 | 137.3 | --- | --- | C2'endo | 0.0 |
| 1 | DB | G | 2391 | --- | --- | 175.7 | 121.8 | --- | --- | C2'endo | 0.403 |
| 1 | DB | U | 2690 | --- | --- | 148.5 | 259.1 | 159.9 | 295.3 | C2'endo | 0.0 |
| 1 | DB | A | 2872 | --- | --- | 152.9 | 188.7 | --- | --- | C2'endo | 0.0 |
| 1 | DB | A | 2873 | --- | --- | 144.5 | 276.9 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 81 | --- | --- | --- | --- | 310.9 | 224.0 | C2'endo | 0.0 |
| 1 | AA | U | 561 | --- | --- | --- | --- | 55.5 | 122.4 | C2'endo | 0.382 |
| 1 | AA | U | 1049 | --- | --- | --- | --- | 344.0 | 28.9 | C2'endo | 0.0 |
| 1 | AA | A | 1157 | --- | --- | --- | --- | 75.7 | 71.0 | C2'endo | 0.172 |
| 1 | AA | A | 1196 | --- | --- | --- | --- | 319.0 | 119.1 | C2'endo | 0.0 |
| 1 | AA | C | 1322 | --- | --- | --- | --- | 51.7 | 196.4 | C2'endo | 0.672 |
| 1 | BB | A | 91 | --- | --- | --- | --- | 72.6 | 139.3 | C2'endo | 0.0 |
| 1 | BB | U | 321 | --- | --- | --- | --- | 333.8 | 295.5 | C2'endo | 0.438 |
| 1 | BB | C | 323 | 93.6 | 50.2 | --- | --- | 158.9 | 24.2 | C2'endo | 0.0 |
| 1 | BB | C | 456 | 19.7 | 83.0 | --- | --- | 52.6 | 145.6 | C2'endo | 0.0 |
| 1 | BB | A | 503 | --- | --- | --- | --- | 237.4 | 23.7 | C2'endo | 0.139 |
| 1 | BB | C | 957 | --- | --- | --- | --- | 48.4 | 211.5 | C2'endo | 0.349 |
| 1 | BB | A | 1046 | 354.8 | 37.3 | --- | --- | 152.4 | 6.4 | C2'endo | 0.0 |
| 1 | BB | U | 1060 | --- | --- | --- | --- | 97.3 | 84.6 | C2'endo | 0.581 |
| 1 | BB | U | 1061 | --- | --- | --- | --- | 23.7 | 190.0 | C2'endo | 0.18 |
| 1 | BB | A | 1427 | --- | --- | --- | --- | 107.3 | 37.8 | C2'endo | 0.0 |
| 1 | BB | A | 1508 | --- | --- | --- | --- | 321.7 | 291.0 | C2'endo | 0.0 |
| 1 | BB | U | 1523 | --- | --- | --- | --- | 277.1 | 11.4 | C2'endo | 0.433 |
| 1 | BB | G | 1674 | --- | --- | --- | --- | 327.5 | 92.3 | C2'endo | 0.0 |
| 1 | BB | U | 1714 | 289.1 | 1.8 | --- | --- | 32.7 | 224.0 | C2'endo | 0.0 |
| 1 | BB | A | 1900 | --- | --- | --- | --- | 277.6 | 18.8 | C2'endo | 0.134 |
| 1 | BB | U | 1943 | --- | --- | --- | --- | 64.3 | 87.4 | C2'endo | 0.69 |
| 1 | BB | U | 2092 | --- | --- | --- | --- | 61.6 | 108.6 | C2'endo | 0.466 |
| 1 | BB | U | 2249 | --- | --- | --- | --- | 309.8 | 329.5 | C2'endo | 0.567 |
| 1 | BB | G | 2250 | --- | --- | --- | --- | 293.4 | 270.7 | C2'endo | 0.052 |
| 1 | BB | G | 2307 | 88.5 | 86.1 | --- | --- | 87.0 | 54.8 | C2'endo | 0.0 |
| 1 | BB | U | 2324 | --- | --- | --- | --- | 260.6 | 246.9 | C2'endo | 0.0 |
| 1 | BB | G | 2345 | --- | --- | --- | --- | 29.8 | 75.4 | C2'endo | 0.0 |
| 1 | BB | A | 2406 | --- | --- | --- | --- | 159.9 | 294.2 | C2'endo | 0.0 |
| 1 | BB | A | 2439 | --- | --- | --- | --- | 105.0 | 30.5 | C2'endo | 0.01 |
| 1 | BB | A | 2602 | --- | --- | --- | --- | 332.8 | 30.1 | C2'endo | 0.0 |
| 1 | BB | G | 2645 | --- | --- | --- | --- | 287.0 | 344.6 | C2'endo | 0.448 |
| 1 | CA | U | 561 | --- | --- | --- | --- | 54.8 | 123.1 | C2'endo | 0.437 |
| 1 | CA | U | 1049 | --- | --- | --- | --- | 344.1 | 29.3 | C2'endo | 0.0 |
| 1 | CA | A | 1157 | --- | --- | --- | --- | 75.8 | 70.6 | C2'endo | 0.201 |
| 1 | CA | C | 1322 | --- | --- | --- | --- | 51.9 | 195.6 | C2'endo | 0.676 |
| 1 | DB | A | 91 | --- | --- | --- | --- | 71.6 | 139.2 | C2'endo | 0.0 |
| 1 | DB | U | 321 | --- | --- | --- | --- | 332.9 | 295.5 | C2'endo | 0.469 |
| 1 | DB | C | 323 | 94.1 | 50.5 | --- | --- | 158.8 | 24.3 | C2'endo | 0.0 |
| 1 | DB | C | 456 | 19.0 | 83.9 | --- | --- | 52.4 | 144.1 | C2'endo | 0.0 |
| 1 | DB | A | 503 | --- | --- | --- | --- | 237.5 | 24.6 | C2'endo | 0.1 |
| 1 | DB | C | 957 | --- | --- | --- | --- | 48.8 | 212.0 | C2'endo | 0.362 |
| 1 | DB | A | 1046 | --- | --- | --- | --- | 265.8 | 19.5 | C2'endo | 0.0 |
| 1 | DB | U | 1061 | --- | --- | --- | --- | 22.9 | 190.9 | C2'endo | 0.164 |
| 1 | DB | A | 1508 | --- | --- | --- | --- | 321.4 | 291.0 | C2'endo | 0.0 |
| 1 | DB | U | 1523 | --- | --- | --- | --- | 277.6 | 11.1 | C2'endo | 0.447 |
| 1 | DB | G | 1674 | --- | --- | --- | --- | 327.2 | 92.3 | C2'endo | 0.0 |
| 1 | DB | U | 1714 | 289.6 | 1.9 | --- | --- | 32.0 | 223.9 | C2'endo | 0.0 |
| 1 | DB | A | 1900 | --- | --- | --- | --- | 275.6 | 18.6 | C2'endo | 0.14 |
| 1 | DB | U | 1943 | --- | --- | --- | --- | 64.7 | 87.7 | C2'endo | 0.69 |
| 1 | DB | U | 2092 | --- | --- | --- | --- | 62.6 | 108.3 | C2'endo | 0.401 |
| 1 | DB | G | 2144 | 139.0 | 6.8 | --- | --- | 331.7 | 236.6 | C2'endo | 0.0 |
| 1 | DB | U | 2249 | --- | --- | --- | --- | 310.5 | 335.2 | C2'endo | 0.582 |
| 1 | DB | G | 2250 | --- | --- | --- | --- | 287.9 | 271.6 | C2'endo | 0.082 |
| 1 | DB | G | 2307 | 88.8 | 84.9 | --- | --- | 87.0 | 54.8 | C2'endo | 0.0 |
| 1 | DB | U | 2324 | --- | --- | --- | --- | 260.0 | 246.4 | C2'endo | 0.0 |
| 1 | DB | G | 2345 | --- | --- | --- | --- | 29.8 | 75.0 | C2'endo | 0.0 |
| 1 | DB | A | 2406 | --- | --- | --- | --- | 160.0 | 295.0 | C2'endo | 0.0 |
| 1 | DB | A | 2439 | --- | --- | --- | --- | 103.0 | 30.5 | C2'endo | 0.01 |
| 1 | DB | A | 2602 | --- | --- | --- | --- | 333.5 | 30.1 | C2'endo | 0.0 |
| 1 | DB | G | 2645 | --- | --- | --- | --- | 286.5 | 344.8 | C2'endo | 0.433 |
| 1 | DB | U | 2756 | --- | --- | --- | --- | 88.2 | 96.8 | C2'endo | 0.227 |