EMDataResource Pseudotorsion Plot Beta Server
RNA adopts complex three-dimensional folding patterns and has key roles in many cellular functions. Many cryoEM-derived structures contain RNA, including ribosomal particles, spliceosomes, RNA viruses, and polymerase complexes, yet procedures for validation of RNA structures are not as well developed as those for proteins.
This prototype web-service for virtual torsion angle validation of RNA structures can be applied to structures determined using cryo-EM as well as other structural methods. Virtual torsion angle plots for nucleic acids are analogous to Ramachandran plots for proteins. The tool evaluates single structures, either by file upload (mmCIF or PDB format) or by entering a PDB id.
The research community has developed simplified ways to represent nucleic acid backbone conformation through use of virtual torsion angles1-3. A common scheme is to define two virtual torsion angles (pseudotorsions), eta (η) and theta (θ) for a nucleotide triplet. The measured (η,θ) pair defines the backbone conformation relative to central residue (i).
The server calculates three varieties of pseudotorsion angles, as shown in the image below. In all definitions, phosphate atom positions are used, but the alternate atom differs: it is either the C4' atom (η,θ), C1' atom (η',θ'), or base origin4,5 position (η",θ").
Virtual torsion angles of the RNA backbone (calculated using DSSR4) are compared against the statistical distribution of a benchmark set of high quality, non-redundant6 RNA structures determined by X-ray crystallography at ≤ 2.5 Å. Separate analyses are performed based on sugar-puckering type (of ~27,000 residues in the benchmark set, ~24,000 are C3'-endo-like, ~3,000 are C2'-endo-like). Output plots and and a downloadable (csv format) table identify probable conformational outliers for any given RNA-containing structure. For comparison, RNA Suiteness7,8 scores are also provided in the csv (for residue i, suiteness of the i-1, i dinucleotide is listed. Suiteness range is 0(poor)-1(excellent). Calculation performed using DSSR).
The 2D plots permit comparison of pseudotorsion pairs for the structure being evaluated (plotted points) against population statistics of the benchmark set (smoothed contours: bar at right indicates benchmark residue count range). Outliers are marked on the plots by red crosses with residue information available on mouse hover. Summary statistics are provided below each plot to indicate the number of residues evaluated and percent outliers. Note that pseudotorsion angles cannot be calculated for terminal residues or around breaks in the polymer chain, so these are excluded from evaluation.
This tool is designed to identify regions of unusual conformation in folded RNA. Outliers can be legitimate but less-common backbone conformations, or they may indicate modelling error.
It may take several minutes to complete calculations for large structures such as ribosomes.
Please direct any questions/suggestions to help@emdataresource.org
- Olson, W. K. Configurational statistics of polynucleotide chains. An updated virtual bond model to treat effects of base stacking. Macromolecules 13, 721-728 (1980).
- Wadley, L. M., Keating, K. S., Duarte, C. M. & Pyle, A. M. Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol 372, 942-957, doi (2007).
- Keating, K. S., Humphris, E. L. & Pyle, A. M. A new way to see RNA. Q Rev Biophys 44, 433-466, doi (2011).
- Lu, X. J., Bussemaker, H. J. & Olson, W. K. DSSR: an integrated software tool for dissecting the spatial structure of RNA. Nucleic Acids Res 43, e142, doi (2015).
- Li, S., Olson, W. K., Lu, X. J. Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures. Nucleic Acids Research 47, W26-W34 (2019). doi
- Leontis, N. B., & Zirbel, C. L. Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking. In RNA 3D Structure Analysis and Prediction, N. Leontis & E. Westhof (Eds.), (Vol. 27, pp. 281-298). Springer Berlin Heidelberg. doi (2012).
- Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R.M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., Berman, H. M. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA 14, 465-81, doi (2008).
- Chen, V. B., Arendall III, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., Richardson, D. C., MolProbity: all-atom structure validation for macromolecular crystallography, Acta Cryst D 66, 12-21, doi (2010)
RNA Pseudotorsion Plots for PDB entry 4v7s
Crystal structure of the E. coli ribosome bound to telithromycin. Deposited 2010-08-05 X-RAY DIFFRACTION resol 3.2547 Å
7407 C3'-endo RNA residues with 117 outliers ( 1.58 % ) from Eta-Theta plot
1233 C2'-endo RNA residues with 148 outliers ( 12.0 % ) from Eta-Theta plot
7407 C3'-endo RNA residues with 115 outliers ( 1.55 % ) from Eta'-Theta' plot
1233 C2'-endo RNA residues with 137 outliers ( 11.11 % ) from Eta'-Theta' plot
7407 C3'-endo RNA residues with 97 outliers ( 1.31 % ) from Eta"-Theta" plot
1233 C2'-endo RNA residues with 82 outliers ( 6.65 % ) from Eta"-Theta" plot
List of Outliers
| Model Number | Chain | Residue Type | Residue Identifier | Eta | Theta | Eta' | Theta' | Eta'' | Theta'' | Sugar Pucker | Suiteness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | AA | U | 4 | 235.5 | 113.5 | --- | --- | --- | --- | C3'endo | 0.242 |
| 1 | AA | U | 5 | 3.3 | 111.3 | 22.9 | 91.5 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 209 | 76.0 | 259.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 352 | 107.1 | 127.4 | 62.8 | 85.6 | 111.0 | 6.2 | C3'endo | 0.0 |
| 1 | AA | A | 353 | 3.1 | 120.5 | 0.9 | 112.4 | --- | --- | C3'endo | 0.064 |
| 1 | AA | U | 421 | 126.4 | 304.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 841 | 94.2 | 303.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 842 | 325.2 | 297.1 | 20.2 | 282.6 | --- | --- | C3'endo | 0.409 |
| 1 | AA | A | 845 | 116.6 | 313.4 | 128.2 | 320.1 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1030 | 84.3 | 20.7 | 51.5 | 26.8 | 4.8 | 26.2 | C3'endo | 0.0 |
| 1 | AA | A | 1145 | 217.8 | 82.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1212 | 299.9 | 91.3 | 294.0 | 67.2 | 150.6 | 23.7 | C3'endo | 0.0 |
| 1 | AA | A | 1398 | 131.9 | 46.9 | 146.7 | 81.0 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1533 | 7.4 | 280.0 | --- | --- | --- | --- | C3'endo | 0.789 |
| 1 | BA | G | 248 | 124.0 | 307.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 277 | 227.4 | 66.5 | 224.2 | 63.7 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 443 | 263.5 | 100.5 | 305.6 | 74.8 | 2.0 | 30.7 | C3'endo | 0.115 |
| 1 | BA | A | 480 | 107.4 | 304.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 546 | 313.3 | 118.7 | 311.4 | 135.3 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 572 | 19.7 | 278.7 | 47.9 | 274.9 | --- | --- | C3'endo | 0.043 |
| 1 | BA | U | 646 | 105.2 | 285.6 | 120.9 | 293.5 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 747 | 333.3 | 14.9 | 358.0 | 8.5 | 140.6 | 11.2 | C3'endo | 0.0 |
| 1 | BA | U | 846 | 306.9 | 84.4 | 320.0 | 95.2 | 307.8 | 92.9 | C3'endo | 0.0 |
| 1 | BA | U | 1066 | 222.4 | 302.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1073 | 281.4 | 315.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1088 | 279.9 | 60.7 | 289.6 | 63.7 | 288.3 | 54.3 | C3'endo | 0.0 |
| 1 | BA | G | 1136 | 18.8 | 165.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1273 | 339.6 | 143.3 | 37.8 | 112.9 | 67.3 | 70.8 | C3'endo | 0.0 |
| 1 | BA | U | 1584 | 353.3 | 302.5 | 9.1 | 291.7 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1729 | 94.2 | 329.4 | 89.4 | 298.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1757 | 344.5 | 331.9 | 348.2 | 312.9 | --- | --- | C3'endo | 0.109 |
| 1 | BA | A | 1969 | 217.3 | 79.0 | --- | --- | --- | --- | C3'endo | 0.678 |
| 1 | BA | U | 1971 | 75.8 | 294.0 | 42.5 | 307.7 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 2055 | 236.2 | 44.6 | 255.4 | 58.3 | 310.9 | 131.7 | C3'endo | 0.0 |
| 1 | BA | C | 2143 | 133.7 | 298.2 | 120.4 | 307.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2144 | 201.8 | 348.4 | 246.0 | 325.9 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 2145 | 322.4 | 266.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 2203 | 51.9 | 105.5 | 50.0 | 81.1 | 76.4 | 342.5 | C3'endo | 0.0 |
| 1 | BA | U | 2402 | 245.3 | 130.2 | 263.4 | 115.3 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 2424 | 64.3 | 359.8 | 61.2 | 333.0 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2428 | 294.2 | 100.4 | 279.8 | 93.8 | 188.4 | 73.5 | C3'endo | 0.0 |
| 1 | BA | G | 2502 | 347.0 | 41.1 | 8.4 | 42.0 | 136.5 | 59.5 | C3'endo | 0.0 |
| 1 | BA | G | 2505 | 339.9 | 136.5 | 346.3 | 144.4 | 336.1 | 126.3 | C3'endo | 0.0 |
| 1 | BA | C | 2573 | 265.6 | 66.5 | 269.2 | 69.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2578 | 53.5 | 123.3 | --- | --- | --- | --- | C3'endo | 0.033 |
| 1 | CA | G | 82 | 50.3 | 263.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 209 | 71.6 | 322.0 | 63.0 | 339.4 | 56.8 | 27.7 | C3'endo | 0.0 |
| 1 | CA | G | 266 | 351.5 | 95.3 | 338.8 | 87.3 | 328.7 | 48.1 | C3'endo | 0.0 |
| 1 | CA | A | 353 | 8.1 | 125.0 | 3.8 | 128.9 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 467 | 269.2 | 293.8 | 285.1 | 288.2 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 723 | 48.1 | 24.9 | 55.7 | 344.7 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 816 | 76.3 | 23.2 | --- | --- | --- | --- | C3'endo | 0.349 |
| 1 | CA | C | 841 | 91.4 | 286.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 842 | 326.1 | 300.5 | 27.1 | 291.3 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 843 | 290.8 | 308.7 | 317.0 | 310.0 | 337.4 | 323.4 | C3'endo | 0.0 |
| 1 | CA | A | 845 | 88.2 | 329.2 | 82.7 | 318.1 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1030 | 83.2 | 65.2 | 92.1 | 52.9 | 151.4 | 54.0 | C3'endo | 0.0 |
| 1 | CA | C | 1054 | 2.9 | 126.7 | 346.6 | 125.0 | 356.3 | 83.5 | C3'endo | 0.0 |
| 1 | CA | G | 1094 | 18.7 | 66.5 | 9.0 | 64.2 | 351.9 | 55.7 | C3'endo | 0.0 |
| 1 | CA | C | 1136 | 301.3 | 352.1 | 34.1 | 339.4 | 73.2 | 4.9 | C3'endo | 0.0 |
| 1 | CA | A | 1167 | 350.8 | 43.1 | 55.6 | 313.6 | 44.8 | 166.7 | C3'endo | 0.022 |
| 1 | CA | U | 1168 | 242.3 | 348.1 | 324.5 | 324.5 | --- | --- | C3'endo | 0.039 |
| 1 | CA | U | 1212 | 313.4 | 71.8 | 289.0 | 59.4 | 169.6 | 29.9 | C3'endo | 0.0 |
| 1 | CA | U | 1224 | 115.5 | 292.1 | 138.0 | 306.5 | 148.0 | 3.6 | C3'endo | 0.0 |
| 1 | CA | U | 1240 | 35.5 | 327.4 | 31.5 | 335.2 | 74.5 | 348.9 | C3'endo | 0.0 |
| 1 | CA | A | 1256 | 259.3 | 102.6 | 239.2 | 89.6 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1257 | 335.2 | 9.6 | 344.7 | 347.1 | 126.4 | 354.0 | C3'endo | 0.0 |
| 1 | CA | U | 1451 | 103.2 | 326.2 | 102.2 | 304.8 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1493 | 266.6 | 35.6 | 355.7 | 359.5 | 77.2 | 0.9 | C3'endo | 0.0 |
| 1 | CA | G | 1530 | 127.9 | 116.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 248 | 129.3 | 294.8 | 102.1 | 301.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 277 | 219.4 | 74.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 311 | 86.3 | 293.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 384 | 325.6 | 276.9 | --- | --- | --- | --- | C3'endo | 0.832 |
| 1 | DA | A | 480 | 92.9 | 304.3 | 80.4 | 284.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 546 | 302.7 | 111.6 | 318.7 | 139.0 | 321.0 | 183.1 | C3'endo | 0.0 |
| 1 | DA | A | 547 | 209.8 | 312.0 | 223.4 | 296.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 572 | 47.6 | 280.9 | 62.5 | 281.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 646 | 220.8 | 289.1 | 236.7 | 272.7 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 751 | 302.9 | 113.1 | 322.5 | 116.0 | 318.6 | 131.3 | C3'endo | 0.0 |
| 1 | DA | A | 781 | 348.4 | 99.3 | 358.4 | 74.5 | 358.4 | 19.7 | C3'endo | 0.0 |
| 1 | DA | U | 846 | 277.2 | 111.6 | 281.0 | 92.0 | 287.8 | 61.7 | C3'endo | 0.0 |
| 1 | DA | A | 933 | 124.2 | 287.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 1045 | 208.6 | 76.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1046 | 321.7 | 51.6 | 330.9 | 21.0 | 138.1 | 10.4 | C3'endo | 0.0 |
| 1 | DA | A | 1088 | 299.3 | 56.1 | 302.9 | 56.1 | 292.6 | 52.4 | C3'endo | 0.0 |
| 1 | DA | A | 1175 | 254.6 | 353.7 | 278.8 | 343.9 | --- | --- | C3'endo | 0.05 |
| 1 | DA | U | 1396 | 351.8 | 327.2 | 6.1 | 297.1 | --- | --- | C3'endo | 0.112 |
| 1 | DA | U | 1523 | 30.9 | 314.7 | 37.2 | 311.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1535 | 93.0 | 278.3 | 85.1 | 295.8 | 91.5 | 345.8 | C3'endo | 0.0 |
| 1 | DA | A | 1583 | 201.9 | 64.0 | 245.6 | 9.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1584 | 52.2 | 275.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1729 | 110.0 | 342.4 | 99.9 | 323.8 | 80.4 | 341.2 | C3'endo | 0.0 |
| 1 | DA | A | 1757 | 345.9 | 331.1 | 348.3 | 309.6 | --- | --- | C3'endo | 0.59 |
| 1 | DA | A | 1969 | 218.2 | 85.2 | --- | --- | --- | --- | C3'endo | 0.616 |
| 1 | DA | C | 2055 | 225.7 | 54.7 | 244.2 | 68.7 | 298.1 | 119.8 | C3'endo | 0.0 |
| 1 | DA | U | 2203 | 47.9 | 101.1 | 50.8 | 63.4 | 92.0 | 341.3 | C3'endo | 0.01 |
| 1 | DA | U | 2305 | 131.8 | 126.4 | 124.5 | 135.5 | 93.8 | 93.1 | C3'endo | 0.0 |
| 1 | DA | C | 2306 | 128.8 | 334.6 | 122.2 | 294.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2307 | 58.7 | 90.1 | 92.8 | 78.5 | 117.1 | 53.3 | C3'endo | 0.037 |
| 1 | DA | U | 2320 | 279.7 | 68.7 | 269.0 | 44.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2321 | 110.6 | 281.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2382 | 228.7 | 65.9 | 224.2 | 71.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2401 | 202.1 | 287.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2423 | 5.4 | 107.1 | 6.4 | 77.4 | 350.1 | 31.5 | C3'endo | 0.0 |
| 1 | DA | C | 2424 | 50.0 | 13.3 | 50.6 | 343.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2502 | 328.0 | 49.2 | 338.3 | 44.0 | 132.0 | 64.8 | C3'endo | 0.0 |
| 1 | DA | G | 2505 | 337.6 | 148.8 | 332.9 | 141.6 | 321.8 | 114.0 | C3'endo | 0.0 |
| 1 | DA | C | 2573 | 252.9 | 64.0 | 238.3 | 65.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2578 | 65.7 | 129.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2797 | 47.4 | 84.2 | 64.0 | 35.8 | --- | --- | C3'endo | 0.724 |
| 1 | DB | C | 35 | 97.5 | 275.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DB | U | 87 | 94.8 | 307.9 | 86.9 | 312.6 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 83 | --- | --- | 238.5 | 134.5 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1031 | --- | --- | 149.9 | 74.7 | 165.9 | 83.9 | C3'endo | 0.0 |
| 1 | BA | A | 412 | --- | --- | 278.0 | 262.0 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 547 | --- | --- | 240.4 | 268.9 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 562 | --- | --- | 290.3 | 155.8 | --- | --- | C3'endo | 0.519 |
| 1 | BA | A | 781 | --- | --- | 349.1 | 87.0 | 345.7 | 26.5 | C3'endo | 0.01 |
| 1 | BA | U | 1065 | --- | --- | 146.1 | 290.3 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 1179 | --- | --- | 147.8 | 290.8 | --- | --- | C3'endo | 0.143 |
| 1 | BA | U | 1779 | --- | --- | 154.9 | 21.7 | 127.5 | 34.1 | C3'endo | 0.322 |
| 1 | BA | A | 1785 | --- | --- | 111.2 | 145.7 | 121.1 | 102.1 | C3'endo | 0.63 |
| 1 | BA | U | 2068 | --- | --- | 292.8 | 58.8 | --- | --- | C3'endo | 0.397 |
| 1 | BA | A | 2267 | --- | --- | 151.0 | 41.9 | --- | --- | C3'endo | 0.018 |
| 1 | BA | A | 2577 | --- | --- | 284.0 | 352.6 | --- | --- | C3'endo | 0.077 |
| 1 | BA | C | 2755 | --- | --- | 353.3 | 152.6 | 348.3 | 102.1 | C3'endo | 0.154 |
| 1 | CA | C | 352 | --- | --- | 91.0 | 83.2 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 397 | --- | --- | 312.3 | 135.9 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 632 | --- | --- | 217.2 | 347.4 | --- | --- | C3'endo | 0.066 |
| 1 | CA | G | 722 | --- | --- | 122.0 | 123.8 | 162.1 | 38.6 | C3'endo | 0.0 |
| 1 | CA | G | 926 | --- | --- | 49.9 | 16.4 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 1303 | --- | --- | 249.7 | 262.9 | 287.7 | 327.2 | C3'endo | 0.0 |
| 1 | CA | A | 1398 | --- | --- | 154.1 | 82.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 87 | --- | --- | 147.6 | 40.2 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 562 | --- | --- | 280.0 | 150.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 613 | --- | --- | 84.2 | 283.5 | 66.6 | 0.4 | C3'endo | 0.0 |
| 1 | DA | U | 653 | --- | --- | 157.7 | 6.8 | 150.8 | 331.7 | C3'endo | 0.01 |
| 1 | DA | G | 1271 | --- | --- | 147.6 | 112.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1458 | --- | --- | 232.3 | 148.4 | --- | --- | C3'endo | 0.01 |
| 1 | DA | U | 1460 | --- | --- | 227.4 | 341.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1779 | --- | --- | 154.8 | 23.1 | 133.8 | 37.2 | C3'endo | 0.08 |
| 1 | DA | A | 2267 | --- | --- | 156.0 | 1.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 2755 | --- | --- | 357.8 | 147.0 | 355.9 | 94.0 | C3'endo | 0.341 |
| 1 | AA | U | 208 | --- | --- | --- | --- | 121.0 | 116.8 | C3'endo | 0.0 |
| 1 | AA | A | 665 | --- | --- | --- | --- | 13.3 | 150.9 | C3'endo | 0.0 |
| 1 | AA | U | 1202 | --- | --- | --- | --- | 316.4 | 292.1 | C3'endo | 0.0 |
| 1 | AA | A | 1377 | --- | --- | --- | --- | 180.9 | 83.7 | C3'endo | 0.525 |
| 1 | AA | A | 1492 | --- | --- | --- | --- | 107.6 | 135.5 | C3'endo | 0.0 |
| 1 | BA | G | 549 | --- | --- | --- | --- | 165.5 | 35.0 | C3'endo | 0.0 |
| 1 | BA | A | 751 | 297.8 | 115.2 | --- | --- | 318.5 | 123.2 | C3'endo | 0.864 |
| 1 | BA | G | 763 | --- | --- | --- | --- | 105.8 | 121.4 | C3'endo | 0.0 |
| 1 | BA | A | 1175 | --- | --- | --- | --- | 256.4 | 347.4 | C3'endo | 0.0 |
| 1 | BA | A | 1274 | --- | --- | --- | --- | 12.0 | 137.4 | C3'endo | 0.208 |
| 1 | BA | A | 1583 | --- | --- | --- | --- | 292.8 | 354.8 | C3'endo | 0.0 |
| 1 | BA | A | 1700 | --- | --- | --- | --- | 342.8 | 296.0 | C3'endo | 0.122 |
| 1 | BA | G | 2529 | --- | --- | --- | --- | 41.5 | 337.7 | C3'endo | 0.0 |
| 1 | BA | G | 2688 | --- | --- | --- | --- | 259.3 | 0.3 | C3'endo | 0.0 |
| 1 | BA | A | 2872 | --- | --- | --- | --- | 121.8 | 137.4 | C3'endo | 0.123 |
| 1 | BA | A | 2883 | --- | --- | --- | --- | 179.0 | 20.9 | C3'endo | 0.0 |
| 1 | CA | A | 465 | --- | --- | --- | --- | 11.2 | 162.8 | C3'endo | 0.241 |
| 1 | CA | A | 466 | --- | --- | --- | --- | 10.0 | 215.2 | C3'endo | 0.0 |
| 1 | CA | A | 665 | --- | --- | --- | --- | 10.4 | 152.4 | C3'endo | 0.0 |
| 1 | CA | U | 1029 | 132.9 | 82.0 | --- | --- | 270.5 | 359.5 | C3'endo | 0.0 |
| 1 | CA | C | 1031 | --- | --- | --- | --- | 197.1 | 35.3 | C3'endo | 0.0 |
| 1 | CA | U | 1135 | --- | --- | --- | --- | 287.3 | 119.9 | C3'endo | 0.462 |
| 1 | CA | U | 1202 | --- | --- | --- | --- | 303.5 | 291.2 | C3'endo | 0.0 |
| 1 | CA | A | 1377 | --- | --- | --- | --- | 186.6 | 77.1 | C3'endo | 0.849 |
| 1 | CA | C | 1533 | --- | --- | --- | --- | 27.6 | 195.9 | C3'endo | 0.621 |
| 1 | DA | U | 139 | 45.6 | 3.1 | --- | --- | 69.8 | 356.8 | C3'endo | 0.0 |
| 1 | DA | A | 221 | --- | --- | --- | --- | 162.1 | 91.0 | C3'endo | 0.0 |
| 1 | DA | C | 385 | --- | --- | --- | --- | 269.1 | 56.7 | C3'endo | 0.0 |
| 1 | DA | G | 549 | --- | --- | --- | --- | 177.2 | 58.8 | C3'endo | 0.0 |
| 1 | DA | A | 644 | --- | --- | --- | --- | 160.0 | 79.9 | C3'endo | 0.409 |
| 1 | DA | U | 827 | 356.2 | 55.5 | --- | --- | 328.3 | 46.1 | C3'endo | 0.0 |
| 1 | DA | A | 1086 | --- | --- | --- | --- | 286.2 | 92.5 | C3'endo | 0.0 |
| 1 | DA | C | 1646 | --- | --- | --- | --- | 188.1 | 29.3 | C3'endo | 0.0 |
| 1 | DA | A | 1700 | --- | --- | --- | --- | 331.3 | 297.7 | C3'endo | 0.0 |
| 1 | DA | A | 1785 | --- | --- | --- | --- | 129.3 | 106.6 | C3'endo | 0.275 |
| 1 | DA | C | 1870 | --- | --- | --- | --- | 6.6 | 313.0 | C3'endo | 0.0 |
| 1 | DA | C | 2104 | --- | --- | --- | --- | 285.7 | 99.3 | C3'endo | 0.0 |
| 1 | DA | A | 2309 | --- | --- | --- | --- | 126.8 | 336.8 | C3'endo | 0.0 |
| 1 | DA | U | 2473 | --- | --- | --- | --- | 60.8 | 339.9 | C3'endo | 0.491 |
| 1 | DA | U | 2477 | --- | --- | --- | --- | 259.1 | 39.8 | C3'endo | 0.78 |
| 1 | DA | G | 2529 | --- | --- | --- | --- | 34.8 | 332.6 | C3'endo | 0.0 |
| 1 | DA | G | 2688 | --- | --- | --- | --- | 270.2 | 1.0 | C3'endo | 0.809 |
| 1 | DA | A | 2820 | --- | --- | --- | --- | 41.8 | 350.2 | C3'endo | 0.0 |
| 1 | DA | A | 2872 | --- | --- | --- | --- | 125.8 | 140.3 | C3'endo | 0.0 |
| 1 | DA | A | 2883 | --- | --- | --- | --- | 181.4 | 348.9 | C3'endo | 0.0 |
| 1 | AA | A | 60 | 312.6 | 161.3 | 41.2 | 133.3 | --- | --- | C2'endo | 0.2 |
| 1 | AA | C | 90 | 135.0 | 155.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 344 | 84.9 | 341.1 | --- | --- | --- | --- | C2'endo | 0.046 |
| 1 | AA | U | 367 | 104.0 | 232.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 413 | 158.2 | 50.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 721 | 85.3 | 100.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 815 | 53.2 | 39.0 | 50.1 | 13.3 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 820 | 170.4 | 4.2 | --- | --- | --- | --- | C2'endo | 0.559 |
| 1 | AA | A | 974 | 78.3 | 71.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 975 | 46.8 | 49.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 1094 | 24.5 | 57.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | C | 1140 | 104.8 | 219.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 1160 | 101.2 | 230.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 1213 | 130.1 | 195.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 1227 | 86.8 | 235.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 1278 | 231.2 | 45.2 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | U | 102 | 330.8 | 214.2 | 344.4 | 193.1 | 341.1 | 141.0 | C2'endo | 0.0 |
| 1 | BA | U | 138 | 224.9 | 2.8 | 233.5 | 344.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 139 | 59.8 | 203.4 | 73.7 | 224.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 162 | 104.5 | 184.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 271 | 116.0 | 136.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 386 | 124.5 | 341.6 | 126.2 | 321.5 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 481 | 158.2 | 43.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 504 | 21.6 | 45.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 532 | 143.6 | 32.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 573 | 242.7 | 196.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 574 | 25.6 | 81.4 | 73.5 | 36.5 | --- | --- | C2'endo | 0.106 |
| 1 | BA | C | 645 | 261.7 | 184.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 945 | 85.8 | 223.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 974 | 85.6 | 82.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1025 | 69.0 | 14.4 | 123.7 | 338.4 | --- | --- | C2'endo | 0.036 |
| 1 | BA | U | 1033 | 44.8 | 218.6 | 21.8 | 196.1 | 352.7 | 137.7 | C2'endo | 0.0 |
| 1 | BA | A | 1070 | 72.2 | 52.6 | 71.4 | 40.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1133 | 142.6 | 74.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1180 | 258.0 | 217.3 | 281.6 | 226.0 | 317.1 | 295.7 | C2'endo | 0.0 |
| 1 | BA | G | 1252 | 358.0 | 239.8 | 38.3 | 206.8 | --- | --- | C2'endo | 0.05 |
| 1 | BA | G | 1452 | 148.6 | 74.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1453 | 248.6 | 346.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1609 | 333.2 | 238.9 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | A | 1713 | 62.3 | 254.3 | --- | --- | --- | --- | C2'endo | 0.342 |
| 1 | BA | A | 1808 | 28.3 | 235.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 1870 | 355.2 | 248.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1992 | 304.1 | 144.8 | --- | --- | --- | --- | C2'endo | 0.114 |
| 1 | BA | A | 2030 | 43.5 | 56.5 | 37.6 | 64.1 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2031 | 124.0 | 76.8 | 131.6 | 15.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 2032 | 307.4 | 172.5 | 11.8 | 135.7 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2147 | 244.4 | 330.3 | 229.1 | 346.3 | 271.2 | 28.9 | C2'endo | 0.0 |
| 1 | BA | A | 2266 | 59.0 | 74.4 | --- | --- | --- | --- | C2'endo | 0.134 |
| 1 | BA | U | 2324 | 183.7 | 22.3 | --- | --- | --- | --- | C2'endo | 0.155 |
| 1 | BA | A | 2425 | 93.8 | 66.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 2491 | 114.6 | 185.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2602 | 35.0 | 72.6 | 36.7 | 35.3 | 14.1 | 22.7 | C2'endo | 0.01 |
| 1 | BA | U | 2689 | 135.2 | 336.8 | 143.6 | 299.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 2751 | 284.7 | 298.3 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | U | 2756 | 102.5 | 164.2 | --- | --- | --- | --- | C2'endo | 0.504 |
| 1 | CA | A | 60 | 310.0 | 164.3 | 44.1 | 125.7 | --- | --- | C2'endo | 0.375 |
| 1 | CA | C | 67 | 137.5 | 188.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 84 | 54.4 | 222.6 | 81.2 | 230.1 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 197 | 98.2 | 150.9 | --- | --- | --- | --- | C2'endo | 0.759 |
| 1 | CA | U | 244 | 40.2 | 50.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 344 | 39.7 | 18.4 | 79.3 | 332.0 | --- | --- | C2'endo | 0.092 |
| 1 | CA | U | 367 | 104.5 | 227.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 532 | 322.8 | 245.8 | 299.6 | 205.3 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 702 | 338.2 | 32.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | G | 721 | 87.5 | 95.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 754 | 148.1 | 281.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 815 | 62.8 | 30.4 | 50.3 | 7.7 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 935 | 58.5 | 236.7 | 69.8 | 214.4 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 961 | 260.1 | 264.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 974 | 68.7 | 64.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 975 | 41.0 | 66.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 977 | 28.8 | 192.3 | 65.8 | 170.4 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 982 | 86.3 | 96.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 994 | 62.0 | 240.0 | --- | --- | --- | --- | C2'endo | 0.164 |
| 1 | CA | G | 1050 | 104.3 | 179.9 | 94.8 | 198.3 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1213 | 115.1 | 202.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1227 | 42.2 | 218.0 | 60.8 | 239.1 | --- | --- | C2'endo | 0.054 |
| 1 | CA | A | 1285 | 101.3 | 140.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1286 | 58.6 | 248.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1287 | 309.8 | 172.2 | 340.2 | 184.3 | 332.0 | 246.5 | C2'endo | 0.0 |
| 1 | CA | G | 1300 | 318.8 | 51.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 85 | 256.4 | 184.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 101 | 115.1 | 41.8 | 135.1 | 322.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 102 | 322.5 | 224.9 | 24.8 | 198.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 126 | 310.6 | 189.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 127 | 158.5 | 37.5 | 197.2 | 11.9 | --- | --- | C2'endo | 0.031 |
| 1 | DA | A | 222 | 258.0 | 218.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 233 | 256.2 | 262.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 241 | 123.7 | 92.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 334 | 145.5 | 59.2 | 180.1 | 3.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 372 | 278.1 | 49.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 423 | 145.2 | 19.0 | 178.1 | 318.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 444 | 95.0 | 148.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 504 | 22.4 | 41.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 532 | 140.3 | 35.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 573 | 249.4 | 192.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 615 | 283.3 | 350.1 | 297.9 | 330.6 | --- | --- | C2'endo | 0.23 |
| 1 | DA | A | 627 | 323.9 | 176.0 | 52.5 | 150.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 671 | 359.2 | 201.9 | 355.8 | 188.2 | 348.3 | 229.0 | C2'endo | 0.0 |
| 1 | DA | G | 859 | 124.3 | 159.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 974 | 64.1 | 92.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1025 | 41.6 | 35.4 | 105.6 | 21.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1033 | 46.2 | 221.9 | 22.2 | 185.9 | 350.7 | 127.5 | C2'endo | 0.0 |
| 1 | DA | G | 1062 | 284.1 | 218.7 | 335.2 | 194.7 | 328.5 | 246.1 | C2'endo | 0.095 |
| 1 | DA | A | 1070 | 127.3 | 334.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1072 | 120.4 | 36.3 | 184.5 | 345.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1133 | 129.9 | 91.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1252 | 1.4 | 234.6 | 38.6 | 204.3 | --- | --- | C2'endo | 0.252 |
| 1 | DA | A | 1254 | 170.1 | 24.9 | --- | --- | --- | --- | C2'endo | 0.198 |
| 1 | DA | U | 1255 | 273.5 | 4.3 | 336.5 | 340.3 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1287 | 49.4 | 236.5 | 55.7 | 235.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1329 | 79.1 | 342.1 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DA | U | 1344 | 154.5 | 5.2 | 193.3 | 332.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1416 | 323.8 | 140.8 | 307.3 | 155.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1453 | 264.3 | 288.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1454 | 111.7 | 208.6 | 162.9 | 211.4 | --- | --- | C2'endo | 0.085 |
| 1 | DA | A | 1508 | 269.2 | 208.9 | 269.3 | 224.8 | 329.2 | 251.5 | C2'endo | 0.0 |
| 1 | DA | A | 1509 | 132.6 | 99.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1609 | 325.2 | 245.1 | --- | --- | --- | --- | C2'endo | 0.03 |
| 1 | DA | U | 1714 | 284.8 | 4.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1808 | 38.2 | 218.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1809 | 143.4 | 272.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1930 | 142.4 | 69.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1963 | 73.5 | 230.8 | 77.0 | 223.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1964 | 282.6 | 359.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1992 | 319.4 | 136.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2030 | 37.5 | 54.1 | 31.8 | 58.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2031 | 134.1 | 74.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2034 | 12.7 | 237.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 2143 | 306.5 | 203.0 | 307.0 | 233.6 | 331.6 | 284.2 | C2'endo | 0.0 |
| 1 | DA | C | 2146 | 29.7 | 207.0 | 64.8 | 190.0 | --- | --- | C2'endo | 0.022 |
| 1 | DA | U | 2210 | 89.3 | 141.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2266 | 66.6 | 64.2 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DA | C | 2338 | 126.9 | 192.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2384 | 186.4 | 13.4 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | DA | C | 2385 | 325.0 | 200.5 | 13.8 | 202.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2425 | 120.6 | 36.7 | 123.9 | 25.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2491 | 125.5 | 173.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2585 | 109.7 | 146.8 | --- | --- | --- | --- | C2'endo | 0.394 |
| 1 | DA | A | 2682 | 118.1 | 212.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2689 | 135.7 | 4.2 | 148.2 | 301.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 2751 | 271.4 | 290.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 8 | --- | --- | 272.1 | 246.1 | 272.6 | 266.3 | C2'endo | 0.056 |
| 1 | AA | A | 50 | --- | --- | 81.5 | 95.7 | 90.4 | 111.6 | C2'endo | 0.0 |
| 1 | AA | A | 72 | --- | --- | 173.1 | 211.1 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 451 | --- | --- | 91.1 | 73.8 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 532 | --- | --- | 313.8 | 215.9 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 983 | --- | --- | 153.1 | 269.1 | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 993 | --- | --- | 162.5 | 210.1 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 1125 | --- | --- | 170.3 | 198.3 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 1159 | --- | --- | 298.7 | 116.9 | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 1201 | --- | --- | 32.8 | 92.3 | 82.7 | 100.5 | C2'endo | 0.034 |
| 1 | BA | C | 140 | --- | --- | 279.6 | 12.7 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 141 | --- | --- | 176.6 | 282.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 196 | --- | --- | 310.4 | 256.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 265 | --- | --- | 75.4 | 155.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 457 | --- | --- | 14.1 | 141.5 | --- | --- | C2'endo | 0.033 |
| 1 | BA | C | 531 | --- | --- | 160.9 | 51.6 | 145.2 | 31.9 | C2'endo | 0.0 |
| 1 | BA | U | 615 | --- | --- | 299.8 | 318.8 | 266.3 | 359.3 | C2'endo | 0.0 |
| 1 | BA | A | 627 | --- | --- | 64.4 | 138.7 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 655 | --- | --- | 34.2 | 149.0 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 1071 | --- | --- | 301.6 | 258.6 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 1072 | --- | --- | 161.3 | 200.7 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1132 | --- | --- | 163.5 | 294.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1325 | --- | --- | 340.2 | 246.8 | --- | --- | C2'endo | 0.044 |
| 1 | BA | G | 1416 | --- | --- | 319.9 | 147.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 1454 | --- | --- | 146.1 | 191.9 | --- | --- | C2'endo | 0.217 |
| 1 | BA | G | 1715 | --- | --- | 31.6 | 100.3 | 79.5 | 119.6 | C2'endo | 0.0 |
| 1 | BA | U | 1758 | --- | --- | 286.1 | 261.6 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2033 | --- | --- | 51.2 | 162.7 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2134 | --- | --- | 40.4 | 202.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2135 | --- | --- | 172.7 | 205.4 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 2146 | --- | --- | 46.7 | 113.0 | 41.6 | 174.7 | C2'endo | 0.0 |
| 1 | BA | A | 2799 | --- | --- | 161.5 | 193.5 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 41 | --- | --- | 336.7 | 314.1 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 8 | --- | --- | 285.3 | 240.5 | 298.7 | 264.4 | C2'endo | 0.0 |
| 1 | CA | A | 50 | --- | --- | 82.0 | 107.0 | 93.4 | 123.5 | C2'endo | 0.08 |
| 1 | CA | A | 81 | --- | --- | 264.2 | 208.4 | 323.2 | 202.4 | C2'endo | 0.0 |
| 1 | CA | U | 85 | --- | --- | 279.8 | 112.0 | --- | --- | C2'endo | 0.0 |
| 1 | CA | G | 94 | --- | --- | 278.8 | 117.3 | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 330 | --- | --- | 25.6 | 194.9 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 368 | --- | --- | 314.8 | 349.3 | 328.2 | 69.5 | C2'endo | 0.018 |
| 1 | CA | A | 533 | --- | --- | 39.8 | 221.9 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 983 | --- | --- | 163.2 | 275.6 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1125 | --- | --- | 152.5 | 194.2 | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 1141 | --- | --- | 173.9 | 201.5 | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 1147 | --- | --- | 180.5 | 201.1 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1159 | --- | --- | 294.8 | 112.1 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1201 | --- | --- | 42.9 | 97.6 | 62.8 | 114.2 | C2'endo | 0.0 |
| 1 | DA | U | 100 | --- | --- | 32.0 | 171.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 141 | --- | --- | 153.2 | 298.3 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 142 | --- | --- | 263.0 | 206.1 | 298.4 | 247.8 | C2'endo | 0.0 |
| 1 | DA | A | 196 | --- | --- | 311.0 | 259.2 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 330 | --- | --- | 140.0 | 207.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 386 | --- | --- | 145.6 | 307.2 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 388 | --- | --- | 148.0 | 199.8 | 93.5 | 152.6 | C2'endo | 0.0 |
| 1 | DA | A | 457 | --- | --- | 30.4 | 133.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 475 | --- | --- | 328.3 | 248.3 | 332.4 | 278.9 | C2'endo | 0.0 |
| 1 | DA | C | 531 | --- | --- | 167.7 | 60.4 | --- | --- | C2'endo | 0.01 |
| 1 | DA | A | 574 | --- | --- | 68.0 | 43.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 655 | --- | --- | 17.9 | 134.0 | 321.4 | 205.5 | C2'endo | 0.0 |
| 1 | DA | G | 729 | --- | --- | 324.6 | 359.4 | --- | --- | C2'endo | 0.01 |
| 1 | DA | U | 746 | --- | --- | 207.4 | 9.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 789 | --- | --- | 250.9 | 310.2 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 932 | --- | --- | 43.4 | 70.0 | 35.8 | 36.5 | C2'endo | 0.0 |
| 1 | DA | U | 1012 | --- | --- | 294.0 | 31.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1061 | --- | --- | 48.2 | 217.1 | 51.5 | 218.2 | C2'endo | 0.01 |
| 1 | DA | A | 1073 | --- | --- | 77.7 | 203.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1076 | --- | --- | 177.2 | 202.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1132 | --- | --- | 171.8 | 295.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1273 | --- | --- | 41.7 | 106.8 | 59.4 | 89.1 | C2'endo | 0.0 |
| 1 | DA | C | 1290 | --- | --- | 175.7 | 206.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1340 | --- | --- | 195.7 | 327.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1345 | --- | --- | 145.5 | 208.3 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1387 | --- | --- | 169.1 | 199.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1537 | --- | --- | 149.3 | 282.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1538 | --- | --- | 302.1 | 169.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1715 | --- | --- | 34.4 | 111.9 | 79.4 | 109.9 | C2'endo | 0.0 |
| 1 | DA | C | 1732 | --- | --- | 337.7 | 314.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1758 | --- | --- | 286.5 | 262.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1816 | --- | --- | 298.2 | 25.2 | --- | --- | C2'endo | 0.134 |
| 1 | DA | A | 2033 | --- | --- | 312.7 | 182.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2833 | --- | --- | 343.1 | 15.0 | 247.3 | 21.5 | C2'endo | 0.01 |
| 1 | DA | A | 2873 | --- | --- | 165.6 | 280.4 | --- | --- | C2'endo | 0.0 |
| 1 | DB | U | 89 | --- | --- | 331.8 | 324.6 | --- | --- | C2'endo | 0.0 |
| 1 | AA | C | 214 | --- | --- | --- | --- | 273.9 | 258.6 | C2'endo | 0.0 |
| 1 | AA | U | 561 | --- | --- | --- | --- | 61.5 | 115.5 | C2'endo | 0.272 |
| 1 | AA | C | 1054 | --- | --- | --- | --- | 338.6 | 86.5 | C2'endo | 0.0 |
| 1 | AA | A | 1157 | --- | --- | --- | --- | 67.2 | 55.5 | C2'endo | 0.477 |
| 1 | AA | U | 1183 | --- | --- | --- | --- | 359.4 | 209.8 | C2'endo | 0.0 |
| 1 | AA | A | 1362 | --- | --- | --- | --- | 147.9 | 277.6 | C2'endo | 0.0 |
| 1 | BA | U | 321 | --- | --- | --- | --- | 330.6 | 298.7 | C2'endo | 0.513 |
| 1 | BA | C | 323 | 98.8 | 40.5 | --- | --- | 159.4 | 29.1 | C2'endo | 0.312 |
| 1 | BA | C | 456 | 293.4 | 144.8 | --- | --- | 53.4 | 158.0 | C2'endo | 0.088 |
| 1 | BA | U | 931 | --- | --- | --- | --- | 336.5 | 73.3 | C2'endo | 0.069 |
| 1 | BA | C | 957 | --- | --- | --- | --- | 48.5 | 207.2 | C2'endo | 0.324 |
| 1 | BA | C | 995 | --- | --- | --- | --- | 356.4 | 73.2 | C2'endo | 0.0 |
| 1 | BA | C | 1045 | --- | --- | --- | --- | 152.7 | 300.3 | C2'endo | 0.0 |
| 1 | BA | U | 1061 | --- | --- | --- | --- | 30.5 | 220.0 | C2'endo | 0.0 |
| 1 | BA | A | 1205 | --- | --- | --- | --- | 312.6 | 15.4 | C2'endo | 0.272 |
| 1 | BA | G | 1674 | --- | --- | --- | --- | 328.9 | 98.8 | C2'endo | 0.0 |
| 1 | BA | G | 1733 | --- | --- | --- | --- | 262.1 | 244.6 | C2'endo | 0.281 |
| 1 | BA | A | 1900 | --- | --- | --- | --- | 263.7 | 19.9 | C2'endo | 0.024 |
| 1 | BA | U | 1943 | --- | --- | --- | --- | 61.6 | 88.7 | C2'endo | 0.504 |
| 1 | BA | U | 2249 | --- | --- | --- | --- | 299.4 | 267.7 | C2'endo | 0.737 |
| 1 | BA | G | 2345 | --- | --- | --- | --- | 17.7 | 79.3 | C2'endo | 0.02 |
| 1 | BA | A | 2406 | --- | --- | --- | --- | 165.9 | 281.6 | C2'endo | 0.0 |
| 1 | BA | A | 2439 | --- | --- | --- | --- | 82.2 | 32.8 | C2'endo | 0.107 |
| 1 | BA | G | 2645 | --- | --- | --- | --- | 301.9 | 335.9 | C2'endo | 0.794 |
| 1 | CA | A | 65 | --- | --- | --- | --- | 351.0 | 6.0 | C2'endo | 0.0 |
| 1 | CA | G | 198 | --- | --- | --- | --- | 260.1 | 243.9 | C2'endo | 0.0 |
| 1 | CA | G | 211 | --- | --- | --- | --- | 159.2 | 301.4 | C2'endo | 0.0 |
| 1 | CA | U | 485 | --- | --- | --- | --- | 2.4 | 142.2 | C2'endo | 0.0 |
| 1 | CA | U | 561 | --- | --- | --- | --- | 50.8 | 121.9 | C2'endo | 0.121 |
| 1 | CA | A | 563 | --- | --- | --- | --- | 101.0 | 27.9 | C2'endo | 0.0 |
| 1 | CA | A | 1157 | --- | --- | --- | --- | 75.5 | 59.7 | C2'endo | 0.05 |
| 1 | CA | U | 1183 | --- | --- | --- | --- | 346.1 | 203.8 | C2'endo | 0.0 |
| 1 | DA | A | 91 | --- | --- | --- | --- | 70.1 | 111.8 | C2'endo | 0.0 |
| 1 | DA | A | 216 | --- | --- | --- | --- | 269.0 | 241.3 | C2'endo | 0.0 |
| 1 | DA | G | 301 | 131.3 | 140.0 | --- | --- | 93.4 | 133.7 | C2'endo | 0.497 |
| 1 | DA | C | 323 | 92.7 | 59.0 | --- | --- | 155.2 | 37.8 | C2'endo | 0.0 |
| 1 | DA | G | 617 | --- | --- | --- | --- | 258.4 | 250.2 | C2'endo | 0.0 |
| 1 | DA | U | 931 | --- | --- | --- | --- | 35.7 | 197.6 | C2'endo | 0.0 |
| 1 | DA | C | 957 | --- | --- | --- | --- | 43.2 | 215.4 | C2'endo | 0.023 |
| 1 | DA | G | 1112 | 273.4 | 166.4 | --- | --- | 261.5 | 237.8 | C2'endo | 0.0 |
| 1 | DA | A | 1126 | --- | --- | --- | --- | 150.1 | 37.0 | C2'endo | 0.783 |
| 1 | DA | G | 1674 | --- | --- | --- | --- | 329.5 | 93.8 | C2'endo | 0.0 |
| 1 | DA | A | 1900 | --- | --- | --- | --- | 266.6 | 23.8 | C2'endo | 0.126 |
| 1 | DA | U | 1943 | --- | --- | --- | --- | 63.6 | 85.7 | C2'endo | 0.0 |
| 1 | DA | U | 2092 | 109.1 | 77.5 | --- | --- | 74.1 | 107.5 | C2'endo | 0.0 |
| 1 | DA | U | 2249 | --- | --- | --- | --- | 303.0 | 279.6 | C2'endo | 0.614 |
| 1 | DA | G | 2250 | --- | --- | --- | --- | 337.4 | 270.8 | C2'endo | 0.0 |
| 1 | DA | G | 2345 | --- | --- | --- | --- | 24.5 | 87.8 | C2'endo | 0.0 |
| 1 | DA | A | 2602 | --- | --- | --- | --- | 14.6 | 28.8 | C2'endo | 0.0 |
| 1 | DB | C | 42 | --- | --- | --- | --- | 165.3 | 278.4 | C2'endo | 0.0 |