EMDataResource Pseudotorsion Plot Beta Server
RNA adopts complex three-dimensional folding patterns and has key roles in many cellular functions. Many cryoEM-derived structures contain RNA, including ribosomal particles, spliceosomes, RNA viruses, and polymerase complexes, yet procedures for validation of RNA structures are not as well developed as those for proteins.
This prototype web-service for virtual torsion angle validation of RNA structures can be applied to structures determined using cryo-EM as well as other structural methods. Virtual torsion angle plots for nucleic acids are analogous to Ramachandran plots for proteins. The tool evaluates single structures, either by file upload (mmCIF or PDB format) or by entering a PDB id.
The research community has developed simplified ways to represent nucleic acid backbone conformation through use of virtual torsion angles1-3. A common scheme is to define two virtual torsion angles (pseudotorsions), eta (η) and theta (θ) for a nucleotide triplet. The measured (η,θ) pair defines the backbone conformation relative to central residue (i).
The server calculates three varieties of pseudotorsion angles, as shown in the image below. In all definitions, phosphate atom positions are used, but the alternate atom differs: it is either the C4' atom (η,θ), C1' atom (η',θ'), or base origin4,5 position (η",θ").
Virtual torsion angles of the RNA backbone (calculated using DSSR4) are compared against the statistical distribution of a benchmark set of high quality, non-redundant6 RNA structures determined by X-ray crystallography at ≤ 2.5 Å. Separate analyses are performed based on sugar-puckering type (of ~27,000 residues in the benchmark set, ~24,000 are C3'-endo-like, ~3,000 are C2'-endo-like). Output plots and and a downloadable (csv format) table identify probable conformational outliers for any given RNA-containing structure. For comparison, RNA Suiteness7,8 scores are also provided in the csv (for residue i, suiteness of the i-1, i dinucleotide is listed. Suiteness range is 0(poor)-1(excellent). Calculation performed using DSSR).
The 2D plots permit comparison of pseudotorsion pairs for the structure being evaluated (plotted points) against population statistics of the benchmark set (smoothed contours: bar at right indicates benchmark residue count range). Outliers are marked on the plots by red crosses with residue information available on mouse hover. Summary statistics are provided below each plot to indicate the number of residues evaluated and percent outliers. Note that pseudotorsion angles cannot be calculated for terminal residues or around breaks in the polymer chain, so these are excluded from evaluation.
This tool is designed to identify regions of unusual conformation in folded RNA. Outliers can be legitimate but less-common backbone conformations, or they may indicate modelling error.
It may take several minutes to complete calculations for large structures such as ribosomes.
Please direct any questions/suggestions to help@emdataresource.org
- Olson, W. K. Configurational statistics of polynucleotide chains. An updated virtual bond model to treat effects of base stacking. Macromolecules 13, 721-728 (1980).
- Wadley, L. M., Keating, K. S., Duarte, C. M. & Pyle, A. M. Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol 372, 942-957, doi (2007).
- Keating, K. S., Humphris, E. L. & Pyle, A. M. A new way to see RNA. Q Rev Biophys 44, 433-466, doi (2011).
- Lu, X. J., Bussemaker, H. J. & Olson, W. K. DSSR: an integrated software tool for dissecting the spatial structure of RNA. Nucleic Acids Res 43, e142, doi (2015).
- Li, S., Olson, W. K., Lu, X. J. Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures. Nucleic Acids Research 47, W26-W34 (2019). doi
- Leontis, N. B., & Zirbel, C. L. Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking. In RNA 3D Structure Analysis and Prediction, N. Leontis & E. Westhof (Eds.), (Vol. 27, pp. 281-298). Springer Berlin Heidelberg. doi (2012).
- Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R.M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., Berman, H. M. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA 14, 465-81, doi (2008).
- Chen, V. B., Arendall III, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., Richardson, D. C., MolProbity: all-atom structure validation for macromolecular crystallography, Acta Cryst D 66, 12-21, doi (2010)
RNA Pseudotorsion Plots for PDB entry 4wq1
Complex of 70S ribosome with tRNA-Tyr and mRNA with C-A mismatch in the first position in the A-site. Deposited 2014-10-21 X-RAY DIFFRACTION resol 3.1 Å
8280 C3'-endo RNA residues with 182 outliers ( 2.2 % ) from Eta-Theta plot
1157 C2'-endo RNA residues with 108 outliers ( 9.33 % ) from Eta-Theta plot
8280 C3'-endo RNA residues with 152 outliers ( 1.84 % ) from Eta'-Theta' plot
1157 C2'-endo RNA residues with 84 outliers ( 7.26 % ) from Eta'-Theta' plot
8280 C3'-endo RNA residues with 137 outliers ( 1.65 % ) from Eta"-Theta" plot
1157 C2'-endo RNA residues with 75 outliers ( 6.48 % ) from Eta"-Theta" plot
List of Outliers
| Model Number | Chain | Residue Type | Residue Identifier | Eta | Theta | Eta' | Theta' | Eta'' | Theta'' | Sugar Pucker | Suiteness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 13 | U | 189 | 298.1 | 321.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | G | 190 | 15.8 | 19.1 | 98.7 | 0.8 | 117.9 | 16.0 | C3'endo | 0.0 |
| 1 | 13 | U | 210 | 265.9 | 74.1 | 246.8 | 75.2 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | C | 352 | 117.3 | 91.0 | 101.0 | 77.5 | 105.4 | 359.0 | C3'endo | 0.0 |
| 1 | 13 | A | 353 | 5.6 | 122.7 | 0.5 | 120.8 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | C | 466 | 53.3 | 293.7 | 76.1 | 289.3 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | U | 723 | 53.5 | 294.8 | 64.7 | 290.3 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | C | 754 | 119.1 | 303.7 | --- | --- | --- | --- | C3'endo | 0.194 |
| 1 | 13 | U | 841 | 57.1 | 26.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | U | 843 | 2.8 | 319.8 | 43.7 | 293.2 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | U | 1125 | 31.6 | 42.5 | 29.9 | 3.2 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | U | 1136 | 106.6 | 356.6 | 105.5 | 324.9 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | A | 1157 | 92.1 | 100.3 | 82.9 | 85.4 | 68.6 | 70.7 | C3'endo | 0.0 |
| 1 | 13 | U | 1212 | 276.2 | 76.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | U | 1240 | 12.9 | 334.3 | 18.8 | 332.8 | 75.3 | 356.0 | C3'endo | 0.0 |
| 1 | 13 | A | 1256 | 213.6 | 90.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | U | 1257 | 352.3 | 335.5 | 347.2 | 329.2 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | U | 1278 | 244.2 | 47.7 | 253.1 | 44.0 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | C | 1336 | 230.6 | 44.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | A | 1446 | 140.0 | 125.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | A | 1451 | 69.0 | 26.0 | 75.9 | 344.6 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | C | 1452 | 115.6 | 106.3 | 143.3 | 134.1 | --- | --- | C3'endo | 0.0 |
| 1 | 13 | G | 1453 | 324.6 | 343.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | A | 1492 | 59.1 | 120.9 | 31.6 | 143.6 | 19.1 | 185.1 | C3'endo | 0.0 |
| 1 | 1K | A | 22 | 119.8 | 77.3 | 110.4 | 83.6 | 107.3 | 131.8 | C3'endo | 0.0 |
| 1 | 3K | C | 19 | 320.5 | 292.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 3K | A | 22 | 123.2 | 109.8 | 106.5 | 130.6 | --- | --- | C3'endo | 0.245 |
| 1 | 1H | G | 248 | 118.3 | 300.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | U | 270L | 351.4 | 102.7 | --- | --- | --- | --- | C3'endo | 0.735 |
| 1 | 1H | U | 270M | 97.2 | 112.8 | 1.3 | 94.6 | 293.3 | 33.4 | C3'endo | 0.0 |
| 1 | 1H | U | 270O | 26.0 | 300.3 | 36.6 | 290.7 | --- | --- | C3'endo | 0.218 |
| 1 | 1H | U | 271C | 77.7 | 294.4 | 44.1 | 305.8 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 275 | 262.4 | 98.3 | 248.2 | 125.8 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 443 | 271.6 | 85.6 | 309.4 | 66.3 | 16.5 | 16.0 | C3'endo | 0.0 |
| 1 | 1H | A | 480 | 110.6 | 296.7 | --- | --- | --- | --- | C3'endo | 0.015 |
| 1 | 1H | A | 572 | 61.0 | 261.1 | --- | --- | --- | --- | C3'endo | 0.468 |
| 1 | 1H | G | 615 | 1.0 | 168.3 | 60.2 | 146.2 | 88.4 | 96.2 | C3'endo | 0.514 |
| 1 | 1H | C | 645 | 41.4 | 8.0 | 57.2 | 317.5 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 654H | 116.6 | 30.4 | --- | --- | --- | --- | C3'endo | 0.189 |
| 1 | 1H | G | 729 | 277.3 | 18.5 | --- | --- | --- | --- | C3'endo | 0.059 |
| 1 | 1H | U | 747 | 318.3 | 32.8 | 343.0 | 15.6 | 142.3 | 12.5 | C3'endo | 0.41 |
| 1 | 1H | A | 751 | 306.6 | 96.3 | 327.7 | 116.7 | 317.9 | 120.0 | C3'endo | 0.761 |
| 1 | 1H | A | 887 | 213.0 | 128.7 | 237.7 | 98.8 | 307.7 | 45.9 | C3'endo | 0.0 |
| 1 | 1H | U | 958 | 315.4 | 88.5 | 2.7 | 62.8 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 1067 | 316.8 | 287.4 | 356.7 | 280.3 | 342.6 | 333.8 | C3'endo | 0.048 |
| 1 | 1H | A | 1070 | 79.5 | 33.8 | 76.8 | 32.5 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 1084 | 335.2 | 299.8 | 11.0 | 281.6 | --- | --- | C3'endo | 0.058 |
| 1 | 1H | A | 1088 | 279.9 | 63.5 | 305.9 | 72.7 | 349.2 | 79.4 | C3'endo | 0.0 |
| 1 | 1H | A | 1096 | 238.5 | 312.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | C | 1135 | 89.5 | 265.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 1136 | 10.7 | 160.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | U | 1142 | 316.9 | 26.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | U | 1273 | 331.2 | 145.1 | 33.0 | 113.8 | 66.8 | 78.9 | C3'endo | 0.0 |
| 1 | 1H | U | 1420 | 35.2 | 298.7 | 62.8 | 275.9 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 1536 | 97.4 | 306.9 | 114.1 | 298.0 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | C | 1585 | 56.1 | 299.0 | 63.5 | 299.8 | 131.2 | 332.8 | C3'endo | 0.404 |
| 1 | 1H | U | 1730 | 70.2 | 282.7 | --- | --- | --- | --- | C3'endo | 0.01 |
| 1 | 1H | U | 1757 | 334.3 | 345.7 | 333.9 | 324.7 | 11.2 | 335.3 | C3'endo | 0.325 |
| 1 | 1H | C | 1965 | 266.3 | 337.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 1971 | 6.6 | 343.9 | 349.5 | 335.6 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 2030 | 11.8 | 102.5 | 36.7 | 98.8 | 18.5 | 77.3 | C3'endo | 0.2 |
| 1 | 1H | C | 2055 | 234.2 | 48.9 | 256.2 | 58.4 | 304.5 | 130.9 | C3'endo | 0.0 |
| 1 | 1H | A | 2119 | 286.5 | 283.5 | --- | --- | --- | --- | C3'endo | 0.06 |
| 1 | 1H | U | 2132 | 22.7 | 348.4 | 38.2 | 353.0 | 113.4 | 339.4 | C3'endo | 0.0 |
| 1 | 1H | G | 2133 | 210.1 | 111.0 | 239.8 | 123.7 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | C | 2145 | 88.0 | 292.0 | 80.4 | 302.2 | --- | --- | C3'endo | 0.045 |
| 1 | 1H | C | 2146 | 212.9 | 99.4 | 232.7 | 70.8 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 2147 | 98.6 | 269.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | U | 2172 | 210.3 | 1.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | U | 2213 | 14.7 | 328.8 | 30.9 | 313.4 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | C | 2424 | 96.7 | 331.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 2428 | 292.6 | 102.1 | 277.5 | 96.7 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 2476 | 83.0 | 261.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 2505 | 343.5 | 140.6 | 346.6 | 138.6 | 331.9 | 121.2 | C3'endo | 0.0 |
| 1 | 1H | G | 2578 | 47.4 | 127.4 | --- | --- | --- | --- | C3'endo | 0.136 |
| 1 | 1H | A | 2712A | 94.3 | 330.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 2765 | 86.4 | 261.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | U | 2797 | 302.7 | 295.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 2833 | 8.5 | 354.0 | 45.7 | 329.8 | --- | --- | C3'endo | 0.0 |
| 1 | 16 | U | 41 | 283.5 | 334.8 | 322.4 | 309.1 | --- | --- | C3'endo | 0.0 |
| 1 | 16 | G | 44 | 285.9 | 127.2 | 306.8 | 90.7 | 298.4 | 67.8 | C3'endo | 0.0 |
| 1 | 1G | C | 352 | 85.0 | 110.8 | 92.6 | 75.3 | 107.8 | 9.2 | C3'endo | 0.0 |
| 1 | 1G | A | 353 | 10.8 | 116.9 | 5.5 | 126.7 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | U | 368 | 281.5 | 337.4 | --- | --- | --- | --- | C3'endo | 0.077 |
| 1 | 1G | U | 421 | 101.2 | 316.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1G | C | 466 | 52.1 | 300.5 | 68.5 | 294.1 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | G | 485 | 295.7 | 65.7 | 261.0 | 82.1 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | U | 723 | 359.4 | 348.7 | 35.1 | 332.0 | 26.7 | 352.5 | C3'endo | 0.0 |
| 1 | 1G | C | 754 | 116.0 | 308.0 | --- | --- | --- | --- | C3'endo | 0.595 |
| 1 | 1G | A | 816 | 68.8 | 29.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1G | U | 841 | 298.6 | 126.1 | 338.5 | 76.8 | 340.6 | 40.9 | C3'endo | 0.0 |
| 1 | 1G | C | 842 | 92.2 | 136.5 | 99.2 | 91.4 | 122.3 | 45.1 | C3'endo | 0.0 |
| 1 | 1G | U | 843 | 15.4 | 309.1 | 45.2 | 296.5 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | G | 1053 | 203.3 | 53.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1G | C | 1054 | 7.8 | 131.9 | 343.2 | 120.5 | 347.9 | 113.4 | C3'endo | 0.0 |
| 1 | 1G | G | 1094 | 17.6 | 54.8 | 6.5 | 58.2 | 355.1 | 49.7 | C3'endo | 0.0 |
| 1 | 1G | U | 1125 | 21.8 | 142.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1G | U | 1136 | 78.4 | 354.2 | 85.1 | 339.8 | 96.0 | 337.7 | C3'endo | 0.0 |
| 1 | 1G | A | 1157 | 77.9 | 83.5 | 78.1 | 88.7 | 76.5 | 58.0 | C3'endo | 0.0 |
| 1 | 1G | U | 1159 | 304.4 | 104.7 | 308.2 | 101.0 | 292.1 | 86.6 | C3'endo | 0.0 |
| 1 | 1G | A | 1183 | 350.2 | 322.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1G | C | 1200 | 221.2 | 38.4 | 224.2 | 20.8 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | U | 1212 | 288.1 | 56.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1G | U | 1257 | 332.3 | 11.4 | 337.8 | 340.0 | 138.5 | 337.7 | C3'endo | 0.0 |
| 1 | 1G | U | 1278 | 244.8 | 62.3 | 239.2 | 54.0 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | G | 1300 | 287.3 | 65.9 | 279.8 | 77.4 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | A | 1398 | 129.4 | 47.9 | 145.0 | 74.2 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | A | 1446 | 134.1 | 132.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1G | U | 1450 | 238.1 | 341.3 | 263.2 | 336.9 | 311.0 | 338.4 | C3'endo | 0.0 |
| 1 | 1G | A | 1451 | 105.3 | 23.0 | 148.0 | 343.3 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | G | 1453 | 350.4 | 334.7 | 319.8 | 354.3 | 344.3 | 344.4 | C3'endo | 0.0 |
| 1 | 1G | A | 1492 | 57.8 | 125.0 | 33.6 | 152.4 | 24.0 | 183.1 | C3'endo | 0.0 |
| 1 | 1L | A | 22 | 114.0 | 129.8 | 99.1 | 138.8 | --- | --- | C3'endo | 0.0 |
| 1 | 2L | A | 22 | 228.5 | 120.1 | 255.4 | 147.0 | --- | --- | C3'endo | 0.0 |
| 1 | 3L | C | 19 | 336.6 | 286.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 3L | A | 22 | 133.5 | 102.8 | 117.8 | 126.7 | --- | --- | C3'endo | 0.364 |
| 1 | 4L | A | 13 | 224.7 | 275.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 90 | 133.6 | 124.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | G | 101 | 35.0 | 336.8 | 34.3 | 351.7 | 108.5 | 8.4 | C3'endo | 0.095 |
| 1 | 14 | U | 161 | 310.6 | 105.2 | 348.8 | 97.1 | 358.2 | 100.9 | C3'endo | 0.0 |
| 1 | 14 | A | 229 | 269.3 | 46.7 | 289.1 | 66.2 | 291.6 | 94.4 | C3'endo | 0.0 |
| 1 | 14 | G | 248 | 118.9 | 293.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 270O | 32.0 | 311.6 | 17.2 | 326.7 | 6.9 | 184.3 | C3'endo | 0.0 |
| 1 | 14 | U | 271C | 55.2 | 308.3 | 46.7 | 304.1 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 405 | 18.1 | 327.9 | 26.1 | 313.4 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 443 | 272.4 | 81.4 | 314.5 | 62.3 | 15.5 | 16.5 | C3'endo | 0.0 |
| 1 | 14 | A | 480 | 109.4 | 300.5 | --- | --- | --- | --- | C3'endo | 0.01 |
| 1 | 14 | A | 572 | 62.2 | 261.9 | --- | --- | --- | --- | C3'endo | 0.212 |
| 1 | 14 | C | 645 | 64.6 | 338.9 | 70.7 | 304.5 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | G | 654H | 107.0 | 298.6 | --- | --- | --- | --- | C3'endo | 0.061 |
| 1 | 14 | U | 747 | 327.1 | 27.7 | 3.2 | 15.2 | 144.0 | 14.7 | C3'endo | 0.194 |
| 1 | 14 | A | 751 | 303.7 | 99.7 | 326.5 | 116.0 | 317.2 | 119.5 | C3'endo | 0.0 |
| 1 | 14 | A | 887 | 102.0 | 299.6 | 101.6 | 302.0 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 958 | 310.3 | 87.9 | 0.5 | 73.7 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 1046 | 294.3 | 65.4 | 288.2 | 57.0 | --- | --- | C3'endo | 0.011 |
| 1 | 14 | G | 1047 | 118.8 | 123.4 | 134.2 | 109.9 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 1061 | 55.9 | 286.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 1088 | 357.6 | 27.9 | 357.0 | 36.6 | 21.6 | 53.3 | C3'endo | 0.0 |
| 1 | 14 | A | 1095 | 2.0 | 61.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 1096 | 266.6 | 273.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | C | 1135 | 82.6 | 270.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | G | 1136 | 11.2 | 165.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 1142 | 297.3 | 44.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 1174 | 82.0 | 274.1 | 78.0 | 269.6 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | G | 1176 | 225.4 | 117.7 | --- | --- | --- | --- | C3'endo | 0.285 |
| 1 | 14 | A | 1177 | 219.6 | 117.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 1273 | 329.5 | 144.3 | 33.6 | 110.0 | 69.2 | 71.7 | C3'endo | 0.0 |
| 1 | 14 | G | 1416 | 322.3 | 114.4 | 306.1 | 132.0 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 1420 | 42.2 | 289.9 | 80.0 | 270.3 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 1444A | 86.5 | 312.9 | 93.2 | 295.4 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 1460 | 39.2 | 286.4 | 14.6 | 305.3 | 1.7 | 54.8 | C3'endo | 0.0 |
| 1 | 14 | C | 1509 | 292.3 | 305.4 | 256.9 | 330.5 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | C | 1585 | 46.9 | 292.9 | 60.6 | 292.0 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 1757 | 333.1 | 345.9 | 329.8 | 325.7 | 7.0 | 330.7 | C3'endo | 0.585 |
| 1 | 14 | A | 1969 | 214.8 | 93.4 | --- | --- | --- | --- | C3'endo | 0.379 |
| 1 | 14 | A | 1971 | 13.2 | 343.8 | 355.3 | 335.6 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | C | 2055 | 229.4 | 49.0 | 250.8 | 57.2 | 305.7 | 121.3 | C3'endo | 0.0 |
| 1 | 14 | U | 2132 | 353.5 | 1.6 | 31.0 | 354.8 | 108.0 | 338.2 | C3'endo | 0.0 |
| 1 | 14 | C | 2145 | 100.6 | 269.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 2167 | 286.1 | 282.6 | 1.3 | 277.5 | --- | --- | C3'endo | 0.126 |
| 1 | 14 | A | 2212 | 135.1 | 78.4 | 144.0 | 79.4 | 191.7 | 33.4 | C3'endo | 0.0 |
| 1 | 14 | U | 2213 | 40.0 | 310.4 | 57.2 | 296.7 | --- | --- | C3'endo | 0.01 |
| 1 | 14 | A | 2267 | 130.9 | 34.9 | 145.6 | 32.5 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | C | 2424 | 95.4 | 337.9 | --- | --- | --- | --- | C3'endo | 0.091 |
| 1 | 14 | G | 2428 | 291.1 | 97.3 | 269.6 | 93.3 | 188.5 | 75.0 | C3'endo | 0.034 |
| 1 | 14 | G | 2505 | 341.0 | 145.3 | 348.4 | 142.8 | 332.3 | 119.6 | C3'endo | 0.0 |
| 1 | 14 | C | 2573 | 264.4 | 63.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | G | 2630 | 354.3 | 162.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 2712A | 96.1 | 333.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 14 | G | 2777 | 337.7 | 94.7 | 323.5 | 61.9 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | G | 2833 | 15.0 | 347.6 | 53.9 | 318.2 | --- | --- | C3'endo | 0.0 |
| 1 | 1J | U | 14 | 348.6 | 5.9 | 354.6 | 285.2 | 311.7 | 311.2 | C3'endo | 0.053 |
| 1 | 1J | A | 15 | 103.5 | 311.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 1J | U | 41 | 273.4 | 335.2 | 315.7 | 312.0 | --- | --- | C3'endo | 0.0 |
| 1 | 1J | C | 88 | 314.3 | 288.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | 13 | A | 722 | --- | --- | 126.4 | 142.8 | 152.9 | 79.7 | C3'endo | 0.224 |
| 1 | 13 | C | 1362A | --- | --- | 129.0 | 359.0 | --- | --- | C3'endo | 0.085 |
| 1 | 13 | A | 1398 | --- | --- | 143.5 | 81.5 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 195 | --- | --- | 211.6 | 329.3 | --- | --- | C3'endo | 0.275 |
| 1 | 1H | C | 456 | --- | --- | 351.0 | 109.8 | 54.2 | 78.7 | C3'endo | 0.189 |
| 1 | 1H | G | 763 | --- | --- | 127.7 | 141.8 | 108.6 | 112.0 | C3'endo | 0.552 |
| 1 | 1H | A | 781 | --- | --- | 352.3 | 86.4 | 345.4 | 24.0 | C3'endo | 0.524 |
| 1 | 1H | U | 1078 | --- | --- | 235.9 | 93.0 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 1086 | --- | --- | 143.4 | 108.7 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 1510 | --- | --- | 221.7 | 74.5 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | G | 2112 | --- | --- | 62.4 | 151.8 | 98.7 | 135.8 | C3'endo | 0.0 |
| 1 | 1H | G | 2131 | --- | --- | 142.5 | 15.2 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | C | 2573 | --- | --- | 258.9 | 55.0 | --- | --- | C3'endo | 0.0 |
| 1 | 1H | A | 2577 | --- | --- | 276.1 | 352.5 | --- | --- | C3'endo | 0.222 |
| 1 | 1H | C | 2755 | --- | --- | 350.8 | 152.5 | 350.4 | 104.1 | C3'endo | 0.0 |
| 1 | 1G | G | 413 | --- | --- | 153.7 | 113.2 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | C | 422 | --- | --- | 221.7 | 70.4 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | A | 977 | --- | --- | 25.4 | 167.0 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | G | 1182 | --- | --- | 227.0 | 72.0 | 278.3 | 341.3 | C3'endo | 0.01 |
| 1 | 1G | C | 1260 | --- | --- | 228.7 | 130.1 | --- | --- | C3'endo | 0.0 |
| 1 | 1G | C | 1362A | --- | --- | 131.4 | 1.9 | --- | --- | C3'endo | 0.203 |
| 1 | 14 | A | 195 | --- | --- | 212.0 | 328.5 | --- | --- | C3'endo | 0.224 |
| 1 | 14 | U | 270M | --- | --- | 228.6 | 93.8 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | C | 456 | --- | --- | 3.5 | 109.5 | 62.8 | 355.1 | C3'endo | 0.063 |
| 1 | 14 | G | 763 | --- | --- | 126.6 | 139.7 | 106.5 | 113.5 | C3'endo | 0.117 |
| 1 | 14 | A | 781 | --- | --- | 345.6 | 88.3 | 343.4 | 25.8 | C3'endo | 0.321 |
| 1 | 14 | A | 1070 | --- | --- | 69.2 | 56.2 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 1175 | --- | --- | 291.2 | 155.5 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | U | 1255 | --- | --- | 300.0 | 348.4 | --- | --- | C3'endo | 0.235 |
| 1 | 14 | A | 1543 | --- | --- | 114.4 | 138.7 | 111.6 | 70.7 | C3'endo | 0.0 |
| 1 | 14 | C | 1965 | --- | --- | 343.3 | 295.1 | --- | --- | C3'endo | 0.125 |
| 1 | 14 | G | 2133 | --- | --- | 237.2 | 122.8 | --- | --- | C3'endo | 0.0 |
| 1 | 14 | A | 2170 | --- | --- | 221.1 | 290.9 | --- | --- | C3'endo | 0.01 |
| 1 | 14 | A | 2320 | --- | --- | 140.0 | 96.5 | 175.1 | 78.7 | C3'endo | 0.492 |
| 1 | 14 | G | 2529 | --- | --- | 45.7 | 22.3 | --- | --- | C3'endo | 0.01 |
| 1 | 14 | A | 2577 | --- | --- | 279.2 | 356.7 | --- | --- | C3'endo | 0.01 |
| 1 | 14 | A | 2750 | --- | --- | 99.8 | 150.0 | 71.1 | 98.8 | C3'endo | 0.0 |
| 1 | 14 | C | 2755 | --- | --- | 345.8 | 150.4 | 349.2 | 94.5 | C3'endo | 0.209 |
| 1 | 14 | A | 2883 | --- | --- | 158.9 | 337.2 | 159.3 | 343.7 | C3'endo | 0.499 |
| 1 | 13 | G | 6 | --- | --- | --- | --- | 136.0 | 112.2 | C3'endo | 0.136 |
| 1 | 13 | A | 465 | --- | --- | --- | --- | 32.2 | 135.7 | C3'endo | 0.06 |
| 1 | 13 | U | 560 | 2.1 | 90.9 | --- | --- | 63.5 | 344.6 | C3'endo | 0.0 |
| 1 | 13 | A | 665 | --- | --- | --- | --- | 16.7 | 163.8 | C3'endo | 0.0 |
| 1 | 13 | G | 1032A | --- | --- | --- | --- | 298.6 | 169.5 | C3'endo | 0.0 |
| 1 | 13 | A | 1183 | 336.7 | 348.7 | --- | --- | 353.7 | 192.0 | C3'endo | 0.0 |
| 1 | 13 | A | 1377 | --- | --- | --- | --- | 169.1 | 86.0 | C3'endo | 0.02 |
| 1 | 13 | U | 1450 | --- | --- | --- | --- | 266.8 | 37.7 | C3'endo | 0.658 |
| 1 | 13 | G | 1505 | --- | --- | --- | --- | 187.5 | 356.6 | C3'endo | 0.0 |
| 1 | 1H | U | 162 | --- | --- | --- | --- | 35.6 | 131.4 | C3'endo | 0.187 |
| 1 | 1H | G | 270N | --- | --- | --- | --- | 71.5 | 92.4 | C3'endo | 0.0 |
| 1 | 1H | G | 271 | --- | --- | --- | --- | 0.8 | 195.2 | C3'endo | 0.0 |
| 1 | 1H | G | 388 | --- | --- | --- | --- | 73.1 | 140.7 | C3'endo | 0.425 |
| 1 | 1H | U | 504 | 327.5 | 92.1 | --- | --- | 352.0 | 347.6 | C3'endo | 0.28 |
| 1 | 1H | A | 654 | --- | --- | --- | --- | 55.0 | 115.7 | C3'endo | 0.0 |
| 1 | 1H | A | 1027 | --- | --- | --- | --- | 38.2 | 171.0 | C3'endo | 0.0 |
| 1 | 1H | A | 1069 | --- | --- | --- | --- | 176.1 | 27.4 | C3'endo | 0.734 |
| 1 | 1H | A | 1095 | --- | --- | --- | --- | 44.3 | 150.4 | C3'endo | 0.0 |
| 1 | 1H | A | 1177 | --- | --- | --- | --- | 261.6 | 34.9 | C3'endo | 0.21 |
| 1 | 1H | A | 1274 | --- | --- | --- | --- | 1.2 | 133.4 | C3'endo | 0.035 |
| 1 | 1H | A | 1508 | --- | --- | --- | --- | 190.3 | 57.3 | C3'endo | 0.0 |
| 1 | 1H | G | 1534 | --- | --- | --- | --- | 43.8 | 163.4 | C3'endo | 0.0 |
| 1 | 1H | C | 1646 | --- | --- | --- | --- | 190.1 | 24.6 | C3'endo | 0.265 |
| 1 | 1H | A | 1700 | --- | --- | --- | --- | 346.8 | 297.0 | C3'endo | 0.023 |
| 1 | 1H | A | 1729 | --- | --- | --- | --- | 25.0 | 129.8 | C3'endo | 0.0 |
| 1 | 1H | U | 1779 | --- | --- | --- | --- | 195.0 | 342.2 | C3'endo | 0.518 |
| 1 | 1H | A | 1785 | --- | --- | --- | --- | 127.9 | 96.5 | C3'endo | 0.057 |
| 1 | 1H | G | 1816 | 312.5 | 13.4 | --- | --- | 289.0 | 83.6 | C3'endo | 0.0 |
| 1 | 1H | A | 2212 | --- | --- | --- | --- | 182.8 | 20.7 | C3'endo | 0.0 |
| 1 | 1H | G | 2529 | --- | --- | --- | --- | 41.8 | 338.0 | C3'endo | 0.0 |
| 1 | 1H | A | 2530 | --- | --- | --- | --- | 119.0 | 145.4 | C3'endo | 0.452 |
| 1 | 1H | U | 2584 | --- | --- | --- | --- | 290.4 | 136.1 | C3'endo | 0.32 |
| 1 | 1H | G | 2872 | --- | --- | --- | --- | 77.1 | 129.6 | C3'endo | 0.0 |
| 1 | 1H | A | 2883 | --- | --- | --- | --- | 165.5 | 344.1 | C3'endo | 0.095 |
| 1 | 1G | G | 6 | --- | --- | --- | --- | 132.4 | 111.6 | C3'endo | 0.051 |
| 1 | 1G | A | 397 | --- | --- | --- | --- | 327.5 | 67.5 | C3'endo | 0.0 |
| 1 | 1G | A | 465 | --- | --- | --- | --- | 30.1 | 156.9 | C3'endo | 0.232 |
| 1 | 1G | A | 665 | --- | --- | --- | --- | 12.9 | 151.3 | C3'endo | 0.0 |
| 1 | 1G | U | 1126 | --- | --- | --- | --- | 284.9 | 41.0 | C3'endo | 0.0 |
| 1 | 1G | U | 1196 | 250.5 | 21.1 | --- | --- | 333.1 | 123.6 | C3'endo | 0.0 |
| 1 | 1G | G | 1202 | --- | --- | --- | --- | 309.1 | 295.1 | C3'endo | 0.0 |
| 1 | 1G | C | 1298 | --- | --- | --- | --- | 175.3 | 88.6 | C3'endo | 0.0 |
| 1 | 1G | G | 1505 | --- | --- | --- | --- | 188.2 | 356.0 | C3'endo | 0.194 |
| 1 | 14 | U | 162 | --- | --- | --- | --- | 142.8 | 51.3 | C3'endo | 0.0 |
| 1 | 14 | C | 264 | --- | --- | --- | --- | 272.9 | 65.4 | C3'endo | 0.0 |
| 1 | 14 | G | 271 | --- | --- | --- | --- | 334.4 | 199.9 | C3'endo | 0.0 |
| 1 | 14 | A | 276 | --- | --- | --- | --- | 127.7 | 124.8 | C3'endo | 0.01 |
| 1 | 14 | G | 351 | --- | --- | --- | --- | 266.1 | 44.0 | C3'endo | 0.75 |
| 1 | 14 | G | 388 | --- | --- | --- | --- | 73.1 | 142.5 | C3'endo | 0.281 |
| 1 | 14 | U | 504 | 329.7 | 91.3 | --- | --- | 345.6 | 350.4 | C3'endo | 0.0 |
| 1 | 14 | A | 654 | --- | --- | --- | --- | 63.5 | 127.6 | C3'endo | 0.0 |
| 1 | 14 | A | 890 | --- | --- | --- | --- | 296.0 | 176.5 | C3'endo | 0.0 |
| 1 | 14 | U | 895 | --- | --- | --- | --- | 263.2 | 47.2 | C3'endo | 0.567 |
| 1 | 14 | U | 1033 | --- | --- | --- | --- | 24.2 | 193.8 | C3'endo | 0.072 |
| 1 | 14 | G | 1173 | --- | --- | --- | --- | 289.8 | 107.7 | C3'endo | 0.685 |
| 1 | 14 | A | 1274 | --- | --- | --- | --- | 7.9 | 134.2 | C3'endo | 0.191 |
| 1 | 14 | C | 1646 | --- | --- | --- | --- | 191.8 | 21.9 | C3'endo | 0.517 |
| 1 | 14 | A | 1700 | --- | --- | --- | --- | 347.2 | 299.6 | C3'endo | 0.0 |
| 1 | 14 | A | 1729 | --- | --- | --- | --- | 24.9 | 141.2 | C3'endo | 0.0 |
| 1 | 14 | U | 1779 | --- | --- | --- | --- | 182.3 | 348.6 | C3'endo | 0.193 |
| 1 | 14 | A | 1785 | --- | --- | --- | --- | 127.3 | 92.0 | C3'endo | 0.432 |
| 1 | 14 | G | 1816 | 312.3 | 14.8 | --- | --- | 287.7 | 84.5 | C3'endo | 0.0 |
| 1 | 14 | G | 2116 | --- | --- | --- | --- | 42.1 | 179.0 | C3'endo | 0.161 |
| 1 | 14 | A | 2117 | --- | --- | --- | --- | 135.6 | 110.4 | C3'endo | 0.0 |
| 1 | 14 | A | 2169 | --- | --- | --- | --- | 34.5 | 180.5 | C3'endo | 0.0 |
| 1 | 14 | U | 2172 | --- | --- | --- | --- | 139.7 | 328.4 | C3'endo | 0.0 |
| 1 | 14 | U | 2438 | --- | --- | --- | --- | 189.1 | 42.0 | C3'endo | 0.241 |
| 1 | 14 | A | 2530 | --- | --- | --- | --- | 123.7 | 143.4 | C3'endo | 0.335 |
| 1 | 14 | U | 2688 | --- | --- | --- | --- | 279.5 | 330.9 | C3'endo | 0.565 |
| 1 | 14 | G | 2872 | --- | --- | --- | --- | 74.5 | 145.2 | C3'endo | 0.0 |
| 1 | 13 | A | 51 | 18.0 | 61.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 13 | A | 60 | 293.9 | 179.6 | 42.6 | 134.6 | --- | --- | C2'endo | 0.049 |
| 1 | 13 | A | 412 | 9.8 | 16.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 13 | G | 631 | 249.9 | 217.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 13 | A | 815 | 70.7 | 25.6 | 56.0 | 0.5 | --- | --- | C2'endo | 0.01 |
| 1 | 13 | U | 820 | 164.2 | 19.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 13 | A | 974 | 81.7 | 58.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 13 | A | 975 | 34.9 | 65.4 | 39.0 | 65.8 | 65.6 | 69.4 | C2'endo | 0.0 |
| 1 | 13 | C | 1027 | 107.4 | 355.6 | 261.0 | 207.2 | 319.3 | 258.9 | C2'endo | 0.317 |
| 1 | 13 | G | 1094 | 21.2 | 62.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1K | G | 7 | 241.8 | 283.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1K | OMG | 17 | 296.4 | 204.7 | 340.7 | 200.4 | 350.0 | 211.0 | C2'endo | 0.0 |
| 1 | 1K | G | 18 | 277.0 | 214.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 3K | OMG | 17 | 321.7 | 239.8 | 322.7 | 206.4 | --- | --- | C2'endo | 0.0 |
| 1 | 3K | G | 18 | 228.9 | 9.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 229 | 281.1 | 22.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 386 | 105.2 | 338.8 | 117.5 | 322.0 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 481 | 162.3 | 38.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 529 | 117.5 | 89.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 532 | 147.5 | 30.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 573 | 251.7 | 193.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | C | 574 | 35.3 | 76.7 | 70.4 | 49.6 | --- | --- | C2'endo | 0.351 |
| 1 | 1H | A | 627 | 304.6 | 193.2 | 46.9 | 160.1 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | U | 895 | 248.0 | 210.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 896 | 316.0 | 135.4 | 21.6 | 185.6 | --- | --- | C2'endo | 0.406 |
| 1 | 1H | G | 974 | 83.7 | 7.0 | 118.8 | 346.4 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | C | 974A | 66.1 | 23.7 | 75.3 | 19.3 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 1025 | 55.5 | 25.2 | 110.7 | 336.0 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | U | 1026 | 126.7 | 158.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 1057 | 267.5 | 197.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | U | 1175 | 271.5 | 166.2 | 286.5 | 161.4 | --- | --- | C2'endo | 0.01 |
| 1 | 1H | G | 1252 | 354.3 | 236.6 | 38.2 | 207.5 | --- | --- | C2'endo | 0.122 |
| 1 | 1H | U | 1454 | 46.3 | 219.9 | --- | --- | --- | --- | C2'endo | 0.324 |
| 1 | 1H | A | 1609 | 1.3 | 208.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 1758 | 249.9 | 276.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 1930 | 148.7 | 72.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 2031 | 111.0 | 74.8 | 125.4 | 5.1 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 2210 | 35.4 | 252.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 2211 | 133.8 | 3.8 | --- | --- | --- | --- | C2'endo | 0.096 |
| 1 | 1H | A | 2266 | 59.5 | 73.4 | --- | --- | --- | --- | C2'endo | 0.821 |
| 1 | 1H | G | 2307 | 77.2 | 99.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 2345 | 39.4 | 100.2 | 36.8 | 67.9 | 31.7 | 83.8 | C2'endo | 0.171 |
| 1 | 1H | A | 2425 | 110.0 | 64.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | U | 2585 | 94.7 | 139.1 | --- | --- | --- | --- | C2'endo | 0.026 |
| 1 | 1H | A | 2602 | 77.2 | 34.2 | 41.7 | 33.9 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 2713 | 58.4 | 239.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1H | U | 2756 | 120.2 | 159.8 | --- | --- | --- | --- | C2'endo | 0.055 |
| 1 | 1H | G | 2867 | 338.7 | 48.9 | --- | --- | --- | --- | C2'endo | 0.528 |
| 1 | 1G | A | 51 | 29.7 | 47.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1G | A | 60 | 296.1 | 175.9 | 43.3 | 133.2 | --- | --- | C2'endo | 0.347 |
| 1 | 1G | A | 130 | 343.3 | 255.5 | --- | --- | --- | --- | C2'endo | 0.608 |
| 1 | 1G | U | 208 | 28.8 | 256.6 | --- | --- | --- | --- | C2'endo | 0.057 |
| 1 | 1G | C | 328 | 280.4 | 18.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1G | A | 344 | 65.3 | 19.1 | --- | --- | --- | --- | C2'endo | 0.67 |
| 1 | 1G | A | 412 | 5.5 | 28.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1G | G | 530 | 196.1 | 33.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1G | A | 532 | 294.0 | 286.7 | 286.6 | 221.2 | 292.6 | 259.6 | C2'endo | 0.0 |
| 1 | 1G | A | 815 | 69.2 | 22.1 | 57.3 | 1.1 | --- | --- | C2'endo | 0.197 |
| 1 | 1G | U | 820 | 157.2 | 18.1 | --- | --- | --- | --- | C2'endo | 0.115 |
| 1 | 1G | U | 982 | 86.0 | 94.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1G | U | 992 | 6.7 | 50.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1G | C | 1452 | 102.2 | 141.9 | --- | --- | --- | --- | C2'endo | 0.02 |
| 1 | 1G | G | 1529 | 85.4 | 352.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1L | C | 20 | 121.4 | 106.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 2L | C | 17 | 134.3 | 342.3 | 187.9 | 298.1 | --- | --- | C2'endo | 0.0 |
| 1 | 3L | OMG | 17 | 336.6 | 189.4 | 323.7 | 195.9 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 322 | 161.1 | 339.9 | --- | --- | --- | --- | C2'endo | 0.156 |
| 1 | 14 | G | 386 | 106.2 | 336.4 | 119.1 | 321.2 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 457 | 347.0 | 183.5 | 11.1 | 149.8 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 481 | 159.4 | 34.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 529 | 121.6 | 89.1 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | 14 | A | 532 | 144.0 | 37.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 573 | 250.2 | 200.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | C | 574 | 31.0 | 81.6 | 70.2 | 46.6 | --- | --- | C2'endo | 0.27 |
| 1 | 14 | A | 616 | 336.1 | 223.3 | --- | --- | --- | --- | C2'endo | 0.321 |
| 1 | 14 | A | 627 | 293.5 | 194.6 | 47.5 | 158.4 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | C | 893 | 252.3 | 212.4 | --- | --- | --- | --- | C2'endo | 0.438 |
| 1 | 14 | C | 974A | 67.5 | 16.9 | 66.7 | 15.8 | --- | --- | C2'endo | 0.069 |
| 1 | 14 | G | 1025 | 21.0 | 73.3 | 104.0 | 39.5 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | U | 1454 | 46.1 | 208.8 | --- | --- | --- | --- | C2'endo | 0.511 |
| 1 | 14 | C | 1493 | 272.9 | 277.7 | 298.0 | 260.6 | 343.7 | 294.9 | C2'endo | 0.0 |
| 1 | 14 | A | 1609 | 5.4 | 210.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 1758 | 256.1 | 269.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 1930 | 147.4 | 70.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 1938 | 3.1 | 254.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | U | 1940 | 103.3 | 86.3 | --- | --- | --- | --- | C2'endo | 0.305 |
| 1 | 14 | U | 1963 | 69.7 | 216.9 | 47.5 | 184.3 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 2031 | 106.5 | 78.6 | 121.1 | 18.4 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 2210 | 47.6 | 249.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 2211 | 51.1 | 92.6 | 184.9 | 325.1 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 2266 | 58.6 | 73.2 | --- | --- | --- | --- | C2'endo | 0.799 |
| 1 | 14 | A | 2346 | 345.2 | 39.9 | 354.1 | 349.0 | 320.2 | 352.8 | C2'endo | 0.0 |
| 1 | 14 | A | 2425 | 110.5 | 59.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 2566 | 281.7 | 16.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | U | 2585 | 92.3 | 140.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 2602 | 91.3 | 8.7 | 43.9 | 22.8 | 349.2 | 31.4 | C2'endo | 0.0 |
| 1 | 14 | U | 2702 | 355.3 | 192.0 | 81.1 | 151.4 | 55.6 | 133.6 | C2'endo | 0.0 |
| 1 | 14 | A | 2713 | 50.2 | 246.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 2732 | 178.4 | 7.1 | 205.4 | 341.5 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 2790 | 231.1 | 338.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 1J | C | 108 | 235.2 | 33.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | 13 | A | 8 | --- | --- | 285.8 | 243.1 | 304.7 | 262.5 | C2'endo | 0.402 |
| 1 | 13 | A | 50 | --- | --- | 72.9 | 89.7 | --- | --- | C2'endo | 0.0 |
| 1 | 13 | A | 344 | --- | --- | 88.7 | 325.2 | --- | --- | C2'endo | 0.0 |
| 1 | 13 | A | 451 | --- | --- | 79.1 | 100.5 | --- | --- | C2'endo | 0.1 |
| 1 | 13 | A | 532 | --- | --- | 291.9 | 238.4 | 285.5 | 263.3 | C2'endo | 0.0 |
| 1 | 13 | C | 842 | --- | --- | 171.5 | 67.3 | --- | --- | C2'endo | 0.04 |
| 1 | 13 | U | 1196 | --- | --- | 301.6 | 27.0 | 324.4 | 119.7 | C2'endo | 0.0 |
| 1 | 13 | A | 1201 | --- | --- | 35.5 | 97.2 | 85.5 | 102.6 | C2'endo | 0.0 |
| 1 | 13 | A | 1363 | --- | --- | 75.6 | 63.1 | --- | --- | C2'endo | 0.0 |
| 1 | 2K | H2U | 21 | --- | --- | 168.4 | 308.2 | --- | --- | C2'endo | 0.0 |
| 1 | 3K | C | 20 | --- | --- | 282.3 | 232.0 | 333.1 | 226.5 | C2'endo | 0.0 |
| 1 | 1H | A | 196 | --- | --- | 328.5 | 241.9 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 278 | --- | --- | 274.0 | 237.8 | 326.0 | 278.6 | C2'endo | 0.0 |
| 1 | 1H | A | 330 | --- | --- | 141.9 | 204.9 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 457 | --- | --- | 15.5 | 148.4 | 27.3 | 156.0 | C2'endo | 0.0 |
| 1 | 1H | G | 530 | --- | --- | 170.9 | 200.1 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | U | 614 | --- | --- | 57.7 | 239.0 | 18.6 | 203.9 | C2'endo | 0.0 |
| 1 | 1H | A | 957 | --- | --- | 85.9 | 213.5 | --- | --- | C2'endo | 0.035 |
| 1 | 1H | G | 1325 | --- | --- | 338.7 | 248.1 | --- | --- | C2'endo | 0.035 |
| 1 | 1H | A | 1913 | --- | --- | 70.7 | 74.8 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | G | 2032 | --- | --- | 21.0 | 198.6 | --- | --- | C2'endo | 0.021 |
| 1 | 1H | A | 2033 | --- | --- | 344.1 | 181.7 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | A | 2060 | --- | --- | 309.6 | 123.2 | --- | --- | C2'endo | 0.0 |
| 1 | 1H | U | 2702 | --- | --- | 85.4 | 146.2 | 53.6 | 134.1 | C2'endo | 0.0 |
| 1 | 1H | U | 2712 | --- | --- | 24.3 | 165.3 | --- | --- | C2'endo | 0.366 |
| 1 | 1G | A | 8 | --- | --- | 286.7 | 241.5 | 304.6 | 260.4 | C2'endo | 0.317 |
| 1 | 1G | A | 50 | --- | --- | 72.6 | 85.3 | --- | --- | C2'endo | 0.0 |
| 1 | 1G | U | 189 | --- | --- | 331.7 | 248.3 | --- | --- | C2'endo | 0.0 |
| 1 | 1G | G | 190 | --- | --- | 107.9 | 335.2 | --- | --- | C2'endo | 0.0 |
| 1 | 1G | U | 209 | --- | --- | 297.0 | 176.6 | --- | --- | C2'endo | 0.0 |
| 1 | 1G | A | 451 | --- | --- | 80.2 | 106.2 | --- | --- | C2'endo | 0.414 |
| 1 | 1G | A | 1201 | --- | --- | 37.9 | 100.5 | 89.0 | 106.7 | C2'endo | 0.0 |
| 1 | 1G | A | 1363 | --- | --- | 78.5 | 59.7 | --- | --- | C2'endo | 0.0 |
| 1 | 1L | C | 83 | --- | --- | 287.1 | 229.1 | --- | --- | C2'endo | 0.0 |
| 1 | 2L | G | 19 | --- | --- | 329.4 | 231.4 | --- | --- | C2'endo | 0.0 |
| 1 | 3L | C | 20 | --- | --- | 294.3 | 236.1 | 324.5 | 234.9 | C2'endo | 0.0 |
| 1 | 14 | A | 196 | --- | --- | 328.3 | 242.5 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 265 | --- | --- | 83.3 | 146.0 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 330 | --- | --- | 141.8 | 202.1 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | U | 562 | --- | --- | 305.2 | 138.4 | --- | --- | C2'endo | 0.427 |
| 1 | 14 | C | 888 | --- | --- | 282.1 | 141.3 | 327.8 | 129.1 | C2'endo | 0.0 |
| 1 | 14 | A | 957 | --- | --- | 86.9 | 212.4 | --- | --- | C2'endo | 0.141 |
| 1 | 14 | G | 1252 | --- | --- | 39.5 | 203.9 | --- | --- | C2'endo | 0.136 |
| 1 | 14 | G | 1325 | --- | --- | 334.8 | 245.6 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | A | 1913 | --- | --- | 78.0 | 87.5 | --- | --- | C2'endo | 0.01 |
| 1 | 14 | A | 2033 | --- | --- | 346.3 | 178.7 | --- | --- | C2'endo | 0.0 |
| 1 | 14 | G | 2345 | --- | --- | 35.7 | 70.1 | 28.3 | 103.7 | C2'endo | 0.114 |
| 1 | 13 | U | 65 | --- | --- | --- | --- | 20.0 | 9.0 | C2'endo | 0.0 |
| 1 | 13 | G | 129A | --- | --- | --- | --- | 306.2 | 31.1 | C2'endo | 0.049 |
| 1 | 13 | G | 388 | --- | --- | --- | --- | 277.7 | 35.6 | C2'endo | 0.0 |
| 1 | 13 | A | 533 | --- | --- | --- | --- | 326.5 | 193.3 | C2'endo | 0.0 |
| 1 | 13 | U | 561 | --- | --- | --- | --- | 59.4 | 121.4 | C2'endo | 0.0 |
| 1 | 13 | C | 934 | --- | --- | --- | --- | 319.1 | 70.8 | C2'endo | 0.0 |
| 1 | 13 | U | 960 | --- | --- | --- | --- | 288.5 | 266.0 | C2'endo | 0.0 |
| 1 | 13 | C | 1054 | --- | --- | --- | --- | 4.1 | 103.6 | C2'endo | 0.0 |
| 1 | 3K | G | 7 | --- | --- | --- | --- | 278.3 | 344.5 | C2'endo | 0.0 |
| 1 | 3K | A | 21 | --- | --- | --- | --- | 340.6 | 88.5 | C2'endo | 0.0 |
| 1 | 1H | G | 321 | --- | --- | --- | --- | 337.0 | 300.6 | C2'endo | 0.127 |
| 1 | 1H | G | 323 | 99.3 | 60.1 | --- | --- | 161.5 | 28.7 | C2'endo | 0.0 |
| 1 | 1H | G | 882 | --- | --- | --- | --- | 317.2 | 229.4 | C2'endo | 0.0 |
| 1 | 1H | C | 995 | --- | --- | --- | --- | 354.4 | 75.3 | C2'endo | 0.067 |
| 1 | 1H | U | 1033 | 5.0 | 242.0 | --- | --- | 352.3 | 142.5 | C2'endo | 0.0 |
| 1 | 1H | U | 1205 | --- | --- | --- | --- | 13.5 | 11.2 | C2'endo | 0.0 |
| 1 | 1H | C | 1428 | --- | --- | --- | --- | 146.4 | 284.3 | C2'endo | 0.0 |
| 1 | 1H | A | 1460 | --- | --- | --- | --- | 343.6 | 88.2 | C2'endo | 0.0 |
| 1 | 1H | C | 1493 | --- | --- | --- | --- | 341.7 | 291.1 | C2'endo | 0.0 |
| 1 | 1H | A | 1543 | --- | --- | --- | --- | 98.1 | 76.3 | C2'endo | 0.0 |
| 1 | 1H | G | 1674 | --- | --- | --- | --- | 332.1 | 97.4 | C2'endo | 0.0 |
| 1 | 1H | A | 1847 | --- | --- | --- | --- | 323.4 | 336.4 | C2'endo | 0.0 |
| 1 | 1H | U | 2249 | --- | --- | --- | --- | 299.2 | 265.0 | C2'endo | 0.416 |
| 1 | 1H | G | 2384 | --- | --- | --- | --- | 263.9 | 257.6 | C2'endo | 0.47 |
| 1 | 1G | G | 129A | --- | --- | --- | --- | 299.2 | 26.2 | C2'endo | 0.028 |
| 1 | 1G | A | 533 | 290.1 | 283.7 | --- | --- | 326.5 | 195.0 | C2'endo | 0.0 |
| 1 | 1G | U | 561 | --- | --- | --- | --- | 54.0 | 120.4 | C2'endo | 0.236 |
| 1 | 1G | G | 630 | --- | --- | --- | --- | 144.6 | 278.2 | C2'endo | 0.0 |
| 1 | 1G | A | 975 | --- | --- | --- | --- | 71.1 | 72.0 | C2'endo | 0.0 |
| 1 | 1G | C | 1027 | --- | --- | --- | --- | 297.6 | 271.9 | C2'endo | 0.3 |
| 1 | 1G | U | 1049 | --- | --- | --- | --- | 348.7 | 30.9 | C2'endo | 0.454 |
| 1 | 1G | U | 1240 | --- | --- | --- | --- | 19.4 | 11.8 | C2'endo | 0.0 |
| 1 | 3L | A | 21 | --- | --- | --- | --- | 342.7 | 95.6 | C2'endo | 0.0 |
| 1 | 14 | A | 278 | 148.3 | 286.2 | --- | --- | 276.5 | 277.1 | C2'endo | 0.026 |
| 1 | 14 | G | 321 | --- | --- | --- | --- | 335.3 | 300.9 | C2'endo | 0.498 |
| 1 | 14 | G | 323 | 96.0 | 51.7 | --- | --- | 159.7 | 27.1 | C2'endo | 0.359 |
| 1 | 14 | C | 995 | --- | --- | --- | --- | 350.9 | 71.6 | C2'endo | 0.048 |
| 1 | 14 | G | 1171 | --- | --- | --- | --- | 282.3 | 275.1 | C2'endo | 0.0 |
| 1 | 14 | U | 1205 | --- | --- | --- | --- | 19.1 | 12.2 | C2'endo | 0.0 |
| 1 | 14 | C | 1428 | --- | --- | --- | --- | 143.5 | 285.7 | C2'endo | 0.0 |
| 1 | 14 | A | 1558 | --- | --- | --- | --- | 101.4 | 55.9 | C2'endo | 0.0 |
| 1 | 14 | G | 1674 | --- | --- | --- | --- | 331.2 | 95.5 | C2'endo | 0.0 |
| 1 | 14 | A | 1698 | --- | --- | --- | --- | 97.5 | 85.0 | C2'endo | 0.174 |
| 1 | 14 | A | 1780 | --- | --- | --- | --- | 272.7 | 250.9 | C2'endo | 0.0 |
| 1 | 14 | A | 1847 | --- | --- | --- | --- | 320.3 | 341.7 | C2'endo | 0.0 |
| 1 | 14 | A | 1900 | --- | --- | --- | --- | 295.3 | 18.8 | C2'endo | 0.039 |
| 1 | 14 | U | 2092 | --- | --- | --- | --- | 74.1 | 119.0 | C2'endo | 0.442 |
| 1 | 14 | U | 2249 | --- | --- | --- | --- | 302.6 | 270.5 | C2'endo | 0.0 |
| 1 | 14 | G | 2250 | --- | --- | --- | --- | 346.7 | 280.6 | C2'endo | 0.483 |
| 1 | 14 | G | 2384 | --- | --- | --- | --- | 260.1 | 257.8 | C2'endo | 0.905 |
| 1 | 14 | U | 2712 | 321.6 | 213.7 | --- | --- | 101.6 | 106.6 | C2'endo | 0.403 |
| 1 | 14 | U | 2756 | 108.0 | 166.2 | --- | --- | 90.2 | 80.9 | C2'endo | 0.664 |